Search Results - "Drewes, L."

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic by Tomkovich, Sarah, Dejea, Christine M, Winglee, Kathryn, Drewes, Julia L, Chung, Liam, Housseau, Franck, Pope, Jillian L, Gauthier, Josee, Sun, Xiaolun, Mühlbauer, Marcus, Liu, Xiuli, Fathi, Payam, Anders, Robert A, Besharati, Sepideh, Perez-Chanona, Ernesto, Yang, Ye, Ding, Hua, Wu, Xinqun, Wu, Shaoguang, White, James R, Gharaibeh, Raad Z, Fodor, Anthony A, Wang, Hao, Pardoll, Drew M, Jobin, Christian, Sears, Cynthia L

“…Mucus-invasive bacterial biofilms are identified on the colon mucosa of approximately 50% of colorectal cancer (CRC) patients and approximately 13% of healthy…”
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MRI characteristics and oncological follow-up of patients with ISUP grade group 4 or 5 prostate cancer by Boschheidgen, M., Schimmöller, L., Kastl, R., Drewes, L. R., Jannusch, K., Radke, K. L., Kirchner, J., Ullrich, T., Niegisch, G., Albers, P., Antoch, G., Radtke, J. P.

“…Objectives To analyze multiparametric MRI (mpMRI) characteristics of patients with International Society of Urological Pathology (ISUP) grade group (GG) 4 or 5…”
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High-resolution bacterial 16S rRNA gene profile meta-analysis and biofilm status reveal common colorectal cancer consortia by Drewes, Julia L., White, James R., Dejea, Christine M., Fathi, Payam, Iyadorai, Thevambiga, Vadivelu, Jamuna, Roslani, April C., Wick, Elizabeth C., Mongodin, Emmanuel F., Loke, Mun Fai, Thulasi, Kumar, Gan, Han Ming, Goh, Khean Lee, Chong, Hoong Yin, Kumar, Sandip, Wanyiri, Jane W., Sears, Cynthia L.

“…Colorectal cancer (CRC) remains the third most common cancer worldwide, with a growing incidence among young adults. Multiple studies have presented…”
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Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models by Queen, Jessica, Domingue, Jada C, White, James Robert, Stevens, Courtney, Udayasuryan, Barath, Nguyen, Tam T D, Wu, Shaoguang, Ding, Hua, Fan, Hongni, McMann, Madison, Corona, Alina, Larman, Tatianna C, Verbridge, Scott S, Housseau, Franck, Slade, Daniel J, Drewes, Julia L, Sears, Cynthia L

“…Fusobacteria are commonly associated with human colorectal cancer (CRC), but investigations are hampered by the absence of a stably colonized murine model…”
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MRI characteristics predict risk of pathological upgrade in patients with ISUP grade group 1 prostate cancer by Boschheidgen, M, Schimmöller, L, Radtke, J P, Kastl, R, Jannusch, K, Lakes, J, Drewes, L R, Radke, K L, Esposito, I, Albers, P, Antoch, G, Ullrich, T, Al-Monajjed, R

“…This study aims to analyse multiparametric MRI (mpMRI) characteristics of patients diagnosed with ISUP grade group (GG) 1 prostate cancer (PC) on initial…”
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MRI in-bore biopsy following MRI/US fusion-guided biopsy in patients with persistent suspicion of clinically significant prostate cancer by Quentin, M., Boschheidgen, M., Radtke, J.P., Spohn, F., Ullrich, T., Drewes, L., Valentin, B., Lakes, J., Al-Monajjed, Arsov, C., Esposito, I., Albers, P., Antoch, G., Schimmöller, L.

“…•Systematic and targeted MRI/US fusion-guided biopsy can miss csPC.•MRI in-bore biopsy detected csPC in 47% after inconclusive MRI/US fusion-guided biopsy.•MRI…”
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Multiparametric MRI characteristics of prostatitis and atrophy in the peripheral zone in men without prostate cancer by Al-Monajjed, R., Radtke, JP, Thomas, M., Boschheidgen, M., Drewes, LR, Ullrich, T, Rau, T., Esposito, I., Antoch, G., Albers, P., Lopez-Cotarelo, C., Schimmöller, L.

“…•Characteristics of prostatitis on MRI can be T2w hypointensity and DCE enhancement, but they seem not specific and/or correlated to the histopathologic…”
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Sporadic colorectal cancer: microbial contributors to disease prevention, development and therapy by Drewes, Julia L, Housseau, Franck, Sears, Cynthia L

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Adult-Attained Height and Colorectal Cancer Risk: A Cohort Study, Systematic Review, and Meta-Analysis by Zhou, Elinor, Wang, Lin, Santiago, Celina N, Nanavati, Julie, Rifkin, Samara, Spence, Emma, Hylind, Linda M, Gills, Joell J, La Luna, Louis, Kafonek, David R, Cromwell, David M, Drewes, Julia L, Sears, Cynthia L, Giardiello, Francis M, Mullin, Gerard E

“…The influence of anthropometric characteristics on colorectal neoplasia biology is unclear. We conducted a systematic review and meta-analysis to determine if…”
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Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps by Chen, Bob, Scurrah, Cherie’ R., McKinley, Eliot T., Simmons, Alan J., Ramirez-Solano, Marisol A., Zhu, Xiangzhu, Markham, Nicholas O., Heiser, Cody N., Vega, Paige N., Rolong, Andrea, Kim, Hyeyon, Sheng, Quanhu, Drewes, Julia L., Zhou, Yuan, Southard-Smith, Austin N., Xu, Yanwen, Ro, James, Jones, Angela L., Revetta, Frank, Berry, Lynne D., Niitsu, Hiroaki, Islam, Mirazul, Pelka, Karin, Hofree, Matan, Chen, Jonathan H., Sarkizova, Siranush, Ng, Kimmie, Giannakis, Marios, Boland, Genevieve M., Aguirre, Andrew J., Anderson, Ana C., Rozenblatt-Rosen, Orit, Regev, Aviv, Hacohen, Nir, Kawasaki, Kenta, Sato, Toshiro, Goettel, Jeremy A., Grady, William M., Zheng, Wei, Washington, M. Kay, Cai, Qiuyin, Sears, Cynthia L., Goldenring, James R., Franklin, Jeffrey L., Su, Timothy, Huh, Won Jae, Vandekar, Simon, Roland, Joseph T., Liu, Qi, Coffey, Robert J., Shrubsole, Martha J., Lau, Ken S.

“…Colorectal cancers (CRCs) arise from precursor polyps whose cellular origins, molecular heterogeneity, and immunogenic potential may reveal diagnostic and…”
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Transmission and clearance of potential procarcinogenic bacteria during fecal microbiota transplantation for recurrent Clostridioides difficile by Drewes, Julia L, Corona, Alina, Sanchez, Uriel, Fan, Yunfan, Hourigan, Suchitra K, Weidner, Melissa, Sidhu, Sarah D, Simner, Patricia J, Wang, Hao, Timp, Winston, Oliva-Hemker, Maria, Sears, Cynthia L

“…BACKGROUNDFecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infection (rCDI) in adults and children, but…”
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Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline by Drewes, Julia L, Szeto, Gregory L, Engle, Elizabeth L, Liao, Zhaohao, Shearer, Gene M, Zink, M Christine, Graham, David R

“…HIV immune pathogenesis is postulated to involve two major mechanisms: 1) chronic innate immune responses that drive T cell activation and apoptosis and 2)…”
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Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats by Gerhart, D Z, Enerson, B E, Zhdankina, O Y, Leino, R L, Drewes, L R

“…A polyclonal affinity-purified antibody to the carboxyl-terminal end of the rat monocarboxylate transporter 1 (MCT1) was generated in chickens and used in…”
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Sporadic colorectal cancer: microbial contributors to disease prevention, development and therapy by Drewes, Julia L, Housseau, Franck, Sears, Cynthia L

“…The gut microbiota has been hailed as an accessory organ, with functions critical to the host including dietary metabolic activities and assistance in the…”
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Distinct Patterns of Tryptophan Maintenance in Tissues during Kynurenine Pathway Activation in Simian Immunodeficiency Virus-Infected Macaques by Drewes, Julia L, Croteau, Joshua D, Shirk, Erin N, Engle, Elizabeth L, Zink, M C, Graham, David R

“…Induction of the kynurenine pathway (KP) of tryptophan (TRP) catabolism has been proposed to contribute to T cell dysfunction during human/simian…”
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Unwanted passengers: Microbes hitchiking in breast cancer metastases by Parida, Sheetal, Drewes, Julia L

“…In a recent Cell paper, Fu et al. bridge descriptive cancer microbiome research with mechanistic and functional insight. With savvy use of antibiotics, the…”
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The Cancer Microbiome: Recent Highlights and Knowledge Gaps by Knippel, Reece J, Drewes, Julia L, Sears, Cynthia L

“…Knowledge of the human microbiome, which is likely a critical factor in the initiation, progression, and prognosis of multiple forms of cancer, is rapidly…”
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Expression of Large Amino Acid Transporter LAT1 in Rat Brain Endothelium by Duelli, Roman, Enerson, Bradley E., Gerhart, David Z., Drewes, Lester R.

“…The expression of the large amino acid transporter, LAT1, was investigated in brain of adult Long-Evans rats. The LAT1 transcript was readily detected in brain…”
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Distribution of monocarboxylate transporters MCT1 and MCT2 in rat retina by Gerhart, D.Z., Leino, R.L., Drewes, L.R.

“…Transport of lactic acid and other monocarboxylates such as pyruvate and the ketone bodies through cellular membranes is facilitated by specific transport…”
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Host responses to mucosal biofilms in the lung and gut by Domingue, Jada C., Drewes, Julia L., Merlo, Christian A., Housseau, Franck, Sears, Cynthia L.

“…The impact of the human microbiome on health and disease is of utmost importance and has been studied intensively in recent years. Microbes promote immune…”
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