Search Results - "Drevets, Wayne C."

Neural circuits underlying the pathophysiology of mood disorders by Price, Joseph L, Drevets, Wayne C

“…Although mood disorders constitute leading causes of disability, until recently little was known about their pathogenesis. The delineation of anatomical…”
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Orbitofrontal Cortex Function and Structure in Depression by DREVETS, WAYNE C.

“…:  The orbitofrontal cortex (OFC) has been implicated in the pathophysiology of major depression by evidence obtained using neuroimaging, neuropathologic, and…”
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Immune targets for therapeutic development in depression: towards precision medicine by Drevets, Wayne C., Wittenberg, Gayle M., Bullmore, Edward T., Manji, Husseini K.

“…Over the past two decades, compelling evidence has emerged indicating that immune mechanisms can contribute to the pathogenesis of major depressive disorder…”
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Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study by Canuso, Carla M, Singh, Jaskaran B, Fedgchin, Maggie, Alphs, Larry, Lane, Rosanne, Lim, Pilar, Pinter, Christine, Hough, David, Sanacora, Gerard, Manji, Husseini, Drevets, Wayne C

“…Objective:The authors compared the efficacy of standard-of-care treatment plus intranasal esketamine or placebo for rapid reduction of symptoms of major…”
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Spatiotemporal dynamics of the brain at rest — Exploring EEG microstates as electrophysiological signatures of BOLD resting state networks by Yuan, Han, Zotev, Vadim, Phillips, Raquel, Drevets, Wayne C., Bodurka, Jerzy

“…Neuroimaging research suggests that the resting cerebral physiology is characterized by complex patterns of neuronal activity in widely distributed functional…”
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Prefrontal control of the amygdala during real-time fMRI neurofeedback training of emotion regulation by Zotev, Vadim, Phillips, Raquel, Young, Kymberly D, Drevets, Wayne C, Bodurka, Jerzy

“…We observed in a previous study (PLoS ONE 6:e24522) that the self-regulation of amygdala activity via real-time fMRI neurofeedback (rtfMRI-nf) with positive…”
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The Subgenual Anterior Cingulate Cortex in Mood Disorders by Drevets, Wayne C., Savitz, Jonathan, Trimble, Michael

“…The anterior cingulate cortex (ACC) ventral to the genu of the corpus callosum has been implicated in the modulation of emotional behavior on the basis of…”
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Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression by Drevets, Wayne C., Price, Joseph L., Furey, Maura L.

“…The neural networks that putatively modulate aspects of normal emotional behavior have been implicated in the pathophysiology of mood disorders by converging…”
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Replication of Scopolamine's Antidepressant Efficacy in Major Depressive Disorder: A Randomized, Placebo-Controlled Clinical Trial by Drevets, Wayne C, Furey, Maura L

“…Background We previously reported that intravenous (IV) scopolamine administration produced rapid and robust antidepressant effects in a sample consisting of…”
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Self-regulation of amygdala activation using real-time FMRI neurofeedback by Zotev, Vadim, Krueger, Frank, Phillips, Raquel, Alvarez, Ruben P, Simmons, W Kyle, Bellgowan, Patrick, Drevets, Wayne C, Bodurka, Jerzy

“…Real-time functional magnetic resonance imaging (rtfMRI) with neurofeedback allows investigation of human brain neuroplastic changes that arise as subjects…”
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Neuroreceptor imaging in depression by Savitz, Jonathan B, Drevets, Wayne C

“…Abstract The in vivo study of receptor binding potential in the human brain is made possible by positron emission tomography (PET) imaging. Here we review PET…”
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Depression-Related Increases and Decreases in Appetite: Dissociable Patterns of Aberrant Activity in Reward and Interoceptive Neurocircuitry by Simmons, W. Kyle, Burrows, Kaiping, Avery, Jason A., Kerr, Kara L., Bodurka, Jerzy, Savage, Cary R., Drevets, Wayne C.

“…Objective:Appetite and weight changes are common but variable diagnostic markers in major depressive disorder: some depressed individuals manifest increased…”
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Keeping the body in mind: Insula functional organization and functional connectivity integrate interoceptive, exteroceptive, and emotional awareness by Simmons, W. Kyle, Avery, Jason A., Barcalow, Joel C., Bodurka, Jerzy, Drevets, Wayne C., Bellgowan, Patrick

“…Relatively discrete experimental literatures have grown to support the insula's role in the domains of interoception, focal exteroceptive attention and…”
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Antidepressant Effects of the Muscarinic Cholinergic Receptor Antagonist Scopolamine: A Review by Drevets, Wayne C, Zarate, Carlos A, Furey, Maura L

“…The muscarinic cholinergic receptor system has been implicated in the pathophysiology of depression, with physiological evidence indicating this system is…”
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Neuropathological and neuromorphometric abnormalities in bipolar disorder: View from the medial prefrontal cortical network by SAVITZ, Jonathan B, PRICE, Joseph L, DREVETS, Wayne C

“…The question of whether BD is primarily a developmental disorder or a progressive, neurodegenerative disorder remains unresolved. Here, we review the…”
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Real-time FMRI neurofeedback training of amygdala activity in patients with major depressive disorder by Young, Kymberly D, Zotev, Vadim, Phillips, Raquel, Misaki, Masaya, Yuan, Han, Drevets, Wayne C, Bodurka, Jerzy

“…Amygdala hemodynamic responses to positive stimuli are attenuated in major depressive disorder (MDD), and normalize with remission. Real-time functional MRI…”
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Localization of Dysfunction in Major Depressive Disorder: Prefrontal Cortex and Amygdala by Murray, Elisabeth A, Wise, Steven P, Drevets, Wayne C

“…Despite considerable effort, the localization of dysfunction in major depressive disorder (MDD) remains poorly understood. We present a hypothesis about its…”
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Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disorders by Wittenberg, Gayle M., Stylianou, Annie, Zhang, Yun, Sun, Yu, Gupta, Ashutosh, Jagannatha, P. S., Wang, Dai, Hsu, Benjamin, Curran, Mark E., Khan, Shahid, Chen, Guang, Bullmore, Edward T., Drevets, Wayne C.

“…Activation of the innate immune system is commonly associated with depression. Immunomodulatory drugs may have efficacy for depressive symptoms that are…”
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Ventral Striatum Response During Reward and Punishment Reversal Learning in Unmedicated Major Depressive Disorder by Robinson, Oliver J., Cools, Roshan, Carlisi, Christina O., Sahakian, Barbara J., Drevets, Wayne C.

“…Objective:Affective biases may underlie many of the key symptoms of major depressive disorder, from anhedonia to altered cognitive performance. Understanding…”
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Amygdala real‐time functional magnetic resonance imaging neurofeedback for major depressive disorder: A review by Young, Kymberly D., Zotev, Vadim, Phillips, Raquel, Misaki, Masaya, Drevets, Wayne C., Bodurka, Jerzy

“…Advances in imaging technologies have allowed for the analysis of functional magnetic resonance imaging data in real‐time (rtfMRI), leading to the development…”
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