Search Results - "Dressler, R. G."
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Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene
Published in Development (Cambridge) (01-12-2001)“…The outgrowth of the ureteric bud from the posterior nephric duct epithelium and the subsequent invasion of the bud into the metanephric mesenchyme initiate…”
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Pax-2 is a DNA-Binding Protein Expressed in Embryonic Kidney and Wilms Tumor
Published in Proceedings of the National Academy of Sciences - PNAS (15-02-1992)“…The murine Pax-2 gene contains a protein coding domain homologous to the Drosophila paired-box, first described in certain developmental control genes of the…”
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Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development
Published in Development (Cambridge) (01-11-1993)“…The conversion of mesenchyme to epithelium during the embryonic development of the mammalian kidney requires reciprocal inductive interactions between the…”
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Oct‐4: a germline‐specific transcription factor mapping to the mouse t‐complex
Published in The EMBO journal (01-07-1990)“…Oct‐4 is a maternally expressed octamer‐binding protein encoded by the murine Oct‐4 gene. It is present in unfertilized oocytes, but also in the inner cell…”
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Glial Cell Line-Derived Neurotrophic Factor Activates the Receptor Tyrosine Kinase RET and Promotes Kidney Morphogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1996)“…The receptor tyrosine kinase RET functions during the development of the kidney and the enteric nervous system, yet no ligand has been identified to date. This…”
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WT1 and PAX-2 Podocyte Expression in Denys-Drash Syndrome and Isolated Diffuse Mesangial Sclerosis
Published in The American journal of pathology (1999)“…Denys-Drash syndrome is a rare disorder of urogenital development characterized by the association of early onset glomerulopathy caused by diffuse mesangial…”
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Expression of Pax-2 in human renal cell carcinoma and growth inhibition by antisense oligonucleotides
Published in Cancer research (Chicago, Ill.) (15-09-1995)“…Renal cell carcinoma (RCC) is the most common malignancy in the adult kidney. Because RCC is generally thought to arise from the epithelium of the proximal…”
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A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine
Published in Genes & development (01-12-1988)“…A mouse gene, Cdx-1, was isolated from an embryonic cDNA library using a Drosophila caudal gene probe. The deduced amino acid sequence of Cdx-1 contains…”
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Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities
Published in Nature (London) (04-03-1993)“…The Pax genes comprise a family of transcription factors active in specific tissues during embryonic development and are associated with at least three…”
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10
Another niche for Notch
Published in Kidney international (01-06-2008)“…The Notch signaling pathway patterns the developing nephron along the proximal–distal axis during renal development. In an adult acute tubular necrosis model,…”
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A polyglutamine expansion disease protein sequesters PTIP to attenuate DNA repair and increase genomic instability
Published in Human molecular genetics (01-10-2012)“…Glutamine (Q) expansion diseases are a family of degenerative disorders caused by the lengthening of CAG triplet repeats present in the coding sequences of…”
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Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development
Published in Cell (20-05-1988)“…The mouse genome contains at least three copies of sequences homologous to the "paired box", a conserved domain in several Drosophila segmentation genes of the…”
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Primary structure and developmental expression pattern of Hox 3.1, a member of the murine Hox 3 homeobox gene cluster
Published in The EMBO journal (01-05-1988)“…The murine Hox 3.1 gene maps to a cluster of homeobox‐containing genes on chromosome 15. We report the primary structure of the Hox 3.1 protein, as deduced…”
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Transcription factors in renal development: the WT1 and Pax-2 story
Published in Seminars in nephrology (01-07-1995)“…The development of a complex, multicellular organ, such as the kidney, from two embryonic progenitor tissues requires the activation and suppression of…”
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Pax-2 controls multiple steps of urogenital development
Published in Development (Cambridge) (01-12-1995)“…Urogenital system development in mammals requires the coordinated differentiation of two distinct tissues, the ductal epithelium and the nephrogenic…”
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Groucho suppresses Pax2 transactivation by inhibition of JNK‐mediated phosphorylation
Published in The EMBO journal (15-10-2003)“…Pax proteins are DNA‐binding transcription factors that regulate embryonic development through the activation and repression of downstream target genes. The…”
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Anterior boundaries of Hox gene expression in mesoderm-derived structures correlate with the linear gene order along the chromosome
Published in Differentiation (London) (01-09-1989)“…The developmental expression patterns of four genes, Hox 1.1, Hox 1.2, Hox 1.3 and Hox 3.1, were examined by in situ hybridization to serial embryonic…”
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BRCT Domain-Containing Protein PTIP Is Essential for Progression through Mitosis
Published in Molecular and Cellular Biology (01-03-2003)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Reduced Pax2 Gene Dosage Increases Apoptosis and Slows the Progression of Renal Cystic Disease
Published in Developmental biology (15-03-2000)“…The murine cpk mouse develops a rapid-onset polycystic kidney disease (PKD) with many similarities to human PKD. During kidney development, the transcription…”
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Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease
Published in Nature medicine (01-04-2005)“…The bone morphogenetic proteins (BMPs) profoundly affect embryonic development, differentiation and disease. BMP signaling is suppressed by cysteine-rich…”
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