Search Results - "Dresel, Mark"
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1
Incorporation of an Isohexide Subunit Improves the Drug-like Properties of Bioactive Compounds
Published in ACS medicinal chemistry letters (09-02-2023)“…An enhanced ability to pre-engineer favorable drug-likeness qualities into bioactive molecules would focus and streamline the drug development process. We find…”
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2
Stereoelectronic Features of a Complex Ketene Dimerization Reaction
Published in Molecules (Basel, Switzerland) (23-12-2021)“…The amidation reaction of a tetrahydroisoquinolin-1-one-4-carboxylic acid is a key step in the multi-kilogram-scale preparation of the antimalarial drug SJ733,…”
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3
Gadolinium Complex for the Catch and Release of Phosphate from Water
Published in Environmental science & technology (18-04-2017)“…The ability of complexes of hard and labile metal ions with one or more open coordination sites to capture phosphates with high affinity and selectivity…”
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4
Protocol for building synthetic protocell membranes that sense redox using synthetic phospholipids and natural lipids
Published in STAR protocols (20-09-2024)“…Sensing is a critical function of artificial cells; however, this is challenging to realize using bottom-up approaches. Here, we present a protocol for…”
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5
The Stability of the Complex and the Basicity of the Anion Impact the Selectivity and Affinity of Tripodal Gadolinium Complexes for Anions
Published in Inorganic chemistry (18-11-2019)“…The affinities and selectivities of lanthanide complexes with open coordination sites for anions vary considerably with the chelate. In order to determine the…”
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Evolution of the SARS‐CoV‐2 proteome in three dimensions (3D) during the first 6 months of the COVID‐19 pandemic
Published in Proteins, structure, function, and bioinformatics (01-05-2022)“…Understanding the molecular evolution of the SARS‐CoV‐2 virus as it continues to spread in communities around the globe is important for mitigation and future…”
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Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first 6 months of the COVID-19 pandemic
Published in Proteins, structure, function, and bioinformatics (27-09-2021)“…Abstract Understanding the molecular evolution of the SARS‐CoV‐2 virus as it continues to spread in communities around the globe is important for mitigation…”
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