Search Results - "Drescher, Marian J."

Analysis of Protein Interactions by Surface Plasmon Resonance by Drescher, Dennis G, Selvakumar, Dakshnamurthy, Drescher, Marian J

“…Surface plasmon resonance is an optical technique that is utilized for detecting molecular interactions, such as interactions that occur between proteins or…”
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Analysis of Dysferlin Direct Interactions with Putative Repair Proteins Links Apoptotic Signaling to Ca2+ Elevation via PDCD6 and FKBP8 by Drescher, Dennis G., Drescher, Marian J., Selvakumar, Dakshnamurthy, Annam, Neeraja P.

“…Quantitative surface plasmon resonance (SPR) was utilized to determine binding strength and calcium dependence of direct interactions between dysferlin and…”
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Surface plasmon resonance (SPR) analysis of binding interactions of proteins in inner-ear sensory epithelia by Drescher, Dennis G, Ramakrishnan, Neeliyath A, Drescher, Marian J

“…Surface plasmon resonance is an optical technique utilized for detecting molecular interactions. Binding of a mobile molecule (analyte) to a molecule…”
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CNGA3 is expressed in inner ear hair cells and binds to an intracellular C-terminus domain of EMILIN1 by Selvakumar, Dakshnamurthy, Drescher, Marian J, Dowdall, Jayme R, Khan, Khalid M, Hatfield, James S, Ramakrishnan, Neeliyath A, Drescher, Dennis G

“…The molecular characteristics of CNG (cyclic nucleotide-gated) channels in auditory/vestibular hair cells are largely unknown, unlike those of CNG mediating…”
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Protein Interaction Analysis by Surface Plasmon Resonance by Drescher, Dennis G, Drescher, Marian J

“…Surface plasmon resonance (SPR) is an optical technique that is utilized for detecting molecular interactions that occur in direct protein-protein…”
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Calcium-dependent Binding of HCN1 Channel Protein to Hair Cell Stereociliary Tip Link Protein Protocadherin 15 CD3 by Ramakrishnan, Neeliyath A., Drescher, Marian J., Barretto, Roberto L., Beisel, Kirk W., Hatfield, James S., Drescher, Dennis G.

“…The cytoplasmic amino terminus of HCN1, the primary full-length HCN isoform expressed in trout saccular hair cells, was found by yeast two-hybrid protocols to…”
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Analysis of Dysferlin Direct Interactions with Putative Repair Proteins Links Apoptotic Signaling to Ca[sup.2+] Elevation via PDCD6 and FKBP8 by Drescher, Dennis G, Drescher, Marian J, Selvakumar, Dakshnamurthy, Annam, Neeraja P

“…Quantitative surface plasmon resonance (SPR) was utilized to determine binding strength and calcium dependence of direct interactions between dysferlin and…”
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The SNARE complex in neuronal and sensory cells by Ramakrishnan, Neeliyath A., Drescher, Marian J., Drescher, Dennis G.

“…Transmitter release at synapses ensures faithful chemical coding of information that is transmitted in the sub-second time frame. The brain, the central unit…”
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Direct Interaction of Otoferlin with Syntaxin 1A, SNAP-25, and the L-type Voltage-gated Calcium Channel CaV1.3 by Ramakrishnan, Neeliyath A., Drescher, Marian J., Drescher, Dennis G.

“…The molecular mechanisms underlying synaptic exocytosis in the hair cell, the auditory and vestibular receptor cell, are not well understood. Otoferlin, a C2…”
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Immunohistochemical localization of adrenergic receptors in the rat organ of corti and spiral ganglion by Khan, Khalid M., Drescher, Marian J., Hatfield, James S., Ramakrishnan, Neeliyath A., Drescher, Dennis G.

“…α1‐, β1‐, and β2‐adrenergic receptors (ARs), which mediate responses to adrenergic input, have been immunohistochemically identified within the organ of Corti…”
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Cyclic Nucleotide-gated Channel α-3 (CNGA3) Interacts with Stereocilia Tip-Link Cadherin 23 + Exon 68 or Alternatively with Myosin VIIa, Two Proteins Required for Hair Cell Mechanotransduction by Selvakumar, Dakshnamurthy, Drescher, Marian J., Drescher, Dennis G.

“…Previously, we obtained evidence for a photoreceptor/olfactory type of CNGA3 transcript in a purified teleost vestibular hair cell preparation with…”
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Surface Plasmon Resonance (SPR) Analysis of Binding Interactions of Inner-Ear Proteins by Drescher, Dennis G, Dakshnamurthy, Selvakumar, Drescher, Marian J, Ramakrishnan, Neeliyath A

“…Surface plasmon resonance is an optical technique that is utilized for detecting molecular interactions. Binding of a mobile molecule (analyte) to a molecule…”
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Calcium Regulates Molecular Interactions of Otoferlin with Soluble NSF Attachment Protein Receptor (SNARE) Proteins Required for Hair Cell Exocytosis by Ramakrishnan, Neeliyath A., Drescher, Marian J., Morley, Barbara J., Kelley, Philip M., Drescher, Dennis G.

“…Mutations in otoferlin, a C2 domain-containing ferlin family protein, cause non-syndromic hearing loss in humans (DFNB9 deafness). Furthermore, transmitter…”
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Dopamine D1A directly interacts with otoferlin synaptic pathway proteins: Ca2+ and phosphorylation underlie an NSF-to-AP2mu1 molecular switch by Selvakumar, Dakshnamurthy, Drescher, Marian J, Deckard, Nathan A, Ramakrishnan, Neeliyath A, Morley, Barbara J, Drescher, Dennis G

“…Dopamine receptors regulate exocytosis via protein-protein interactions (PPIs) as well as via adenylyl cyclase transduction pathways. Evidence has been…”
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HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2 by Ramakrishnan, Neeliyath A, Drescher, Marian J, Khan, Khalid M, Hatfield, James S, Drescher, Dennis G

“…A unique coupling between HCN1 and stereociliary tip-link protein protocadherin 15 has been described for a teleost vestibular hair-cell model and mammalian…”
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Identification of the porosome complex in the hair cell by Drescher, Dennis G., Cho, Won Jin, Drescher, Marian J.

“…Porosomes are proposed to be the universal secretory machinery of the cell plasma membrane, where membrane‐bound secretory vesicles transiently dock and fuse…”
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Selective expression of serotonin receptor transcripts in the mammalian cochlea and its subdivisions by Oh, Charles K, Drescher, Marian J, Hatfield, James S, Drescher, Dennis G

“…Expression of serotonin receptor (5-HTR) mRNA has been determined in the mammalian cochlea and its subdivisions by reverse transcriptase-polymerase chain…”
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Immunohistochemical localization of adenylyl cyclase isoforms in the lateral wall of the rat cochlea by Drescher, Marian J, Khan, Khalid M, Hatfield, James S, Shakir, Ali H, Drescher, Dennis G

“…The enzymatic activity of adenylyl cyclase (AC) is attributable to nine isoforms with individual pharmacology and tissue distribution. Polyclonal antibodies…”
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Quantitative analysis of dopamine receptor messages in the mouse cochlea by Karadaghy, Ahmad A, Lasak, John M, Chomchai, Joseph S, Khan, Khalid M, Drescher, Marian J, Drescher, Dennis G

“…Dopamine receptor isoforms were examined in the cochlea of the CBA J mouse by RT-PCR analysis and nucleotide sequencing, utilizing primers specific for known…”
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Analysis of Dysferlin Direct Interactions with Putative Repair Proteins Links Apoptotic Signaling to Ca 2+ Elevation via PDCD6 and FKBP8 by Drescher, Dennis G, Drescher, Marian J, Selvakumar, Dakshnamurthy, Annam, Neeraja P

“…Quantitative surface plasmon resonance (SPR) was utilized to determine binding strength and calcium dependence of direct interactions between dysferlin and…”
Get full text