Search Results - "Dreja, H"
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PO-146 Knockout validation of antibodies to components of the NF-kB signalling pathway
Published in ESMO open (01-07-2018)“…IntroductionNuclear factor-κB (NF-κB) plays a pivotal role in inflammation and innate immunity and aberrant regulation of NF-κB can influence cancer…”
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P04-35. Neutralisation activity in a geographically diverse East London cohort of HIV-1 infected patients
Published in Retrovirology (22-10-2009)“…Doc number: P63…”
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Induction of Long-Term Protective Antiviral Endogenous Immune Response by Short Neutralizing Monoclonal Antibody Treatment
Published in Journal of Virology (01-05-2005)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effects of virion surface gp120 density on infection by HIV-1 and viral production by infected cells
Published in Virology (New York, N.Y.) (05-02-2005)“…The quantity of envelope glycoprotein molecules (Env) on HIV-1 particles is still an issue of debate and, depending on the strain of virus and the nature of…”
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A novel doxycycline inducible autoregulatory plasmid which displays 'on'/'off' regulation suited to gene therapy applications
Published in Gene therapy (01-12-2000)“…The development of transcriptionally controlled systems which function in eukaryotic cells are important for achieving regulated gene expression in gene…”
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Monoclonal antibody-based genetic immunotherapy
Published in Current gene therapy (01-09-2004)“…The clinical application potential of monoclonal antibodies concerns a wide range of diseases including, among others, viral infections, cancer and autoimmune…”
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Monoclonal Antibody 667 Recognizes the Variable Region A Motif of the Ecotropic Retrovirus CasBrE Envelope Glycoprotein and Inhibits Env Binding to the Viral Receptor
Published in Journal of Virology (01-10-2003)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Immuno- and genetic therapy in autoimmune diseases
Published in Genes and immunity (01-06-2000)“…Animal models of autoimmune disease have been developed that mimic some aspects of the pathophysiology of human disease. These models have increased our…”
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Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis
Published in The Journal of experimental medicine (02-08-1999)“…Galectin-1 (GAL-1), a member of a family of conserved beta-galactoside-binding proteins, has been shown to induce in vitro apoptosis of activated T cells and…”
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Targeting cytokines to inflammation sites
Published in Nature biotechnology (01-11-2003)“…To increase the half-life of a cytokine and target its activation specifically to disease sites, we have engineered a latent cytokine using the…”
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Neutralization activity in a geographically diverse East London cohort of human immunodeficiency virus type 1-infected patients: clade C infection results in a stronger and broader humoral immune response than clade B infection
Published in Journal of general virology (01-11-2010)“…The array of human immunodeficiency virus (HIV) subtypes encountered in East London, an area long associated with migration, is unusually heterogeneous,…”
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Engineering of vesicular stomatitis virus-G protein (VSV-G) to retarget recombinant infectious retroviral particles
Published in Molecular therapy (2004)Get full text
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The effects of N-terminal insertion into VSV-G of an scFv peptide
Published in Virology journal (02-09-2006)“…Recombinant retroviruses, including lentiviruses, are the most widely used vectors for both in vitro and in vivo stable gene transfer. However, the inability…”
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Immunotherapy of auto-immune diseases by gene transfer
Published in Biochemical Society transactions (01-12-1999)Get more information
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Lower frequency of apolipoprotein E4 allele in an “elderly” Down's syndrome population
Published in Biological psychiatry (1969) (15-10-1996)Get full text
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Gene therapy for rheumatoid arthritis: Theoretical considerations
Published in Drugs & aging (1998)“…Current understanding of the pathogenesis of rheumatoid arthritis has provided evidence that therapeutic benefit can be achieved by using antagonists targeted…”
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Soluble complement receptor 1 (CD35) delivered by retrovirally infected syngeneic cells or by naked DNA injection prevents the progression of collagen‐induced arthritis
Published in Arthritis and rheumatism (01-08-2000)“…Objective The complement system is important in the development of autoimmune inflammation, including rheumatoid arthritis (RA) and collagen‐induced arthritis…”
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Engineering T cells and molecules for targeting joints and inflammation
Published in Arthritis research (2001)Get full text
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