Search Results - "Dreixler, John C."

Mitogen-activated protein kinase phosphatase-1 (MKP-1) in retinal ischemic preconditioning by Dreixler, John C., Bratton, Anthony, Du, Eugenie, Shaikh, Afzhal R., Savoie, Brian, Alexander, Michael, Marcet, Marcus M., Roth, Steven

“…We previously described the phenomenon of retinal ischemic pre-conditioning (IPC) and we have shown the role of various signaling proteins in the protective…”
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Involvement of Erythropoietin in Retinal Ischemic Preconditioning by DREIXLER, John C, HAGEVIK, Sarah, HEMMERT, Jonathan W, SHAIKH, Afzhal R, ROSENBAUM, Daniel M, ROTH, Steven

“…The purpose of this study was to examine the role of erythropoietin in retinal ischemic preconditioning (IPC). Rats were subjected to retinal ischemia after…”
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Modulation of recombinant and native neuronal SK channels by the neuroprotective drug riluzole by Cao, Ying-Jun, Dreixler, John C, Couey, Jonathan J, Houamed, Khaled M

“…Small conductance, Ca2+-activated K+ channels (SK channels) regulate neuronal excitability. We used patch clamp to study the actions of the neuroprotective…”
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Bone-marrow mesenchymal stem-cell administration significantly improves outcome after retinal ischemia in rats by Mathew, Biji, Poston, Jacqueline N., Dreixler, John C., Torres, Leianne, Lopez, Jasmine, Zelkha, Ruth, Balyasnikova, Irina, Lesniak, Maciej S., Roth, Steven

“…Purpose Ischemia-associated retinal degeneration is one of the leading causes of vision loss, and to date, there are no effective treatment options. We…”
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Hypoxic-Preconditioned Bone Marrow Stem Cell Medium Significantly Improves Outcome After Retinal Ischemia in Rats by Roth, Steven, Dreixler, John C, Mathew, Biji, Balyasnikova, Irina, Mann, Jacob R, Boddapati, Venkat, Xue, Lai, Lesniak, Maciej S

“…We have previously demonstrated the protective effect of bone marrow stem cell (BMSC)-conditioned medium in retinal ischemic injury. We hypothesized here that…”
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Delayed administration of bone marrow mesenchymal stem cell conditioned medium significantly improves outcome after retinal ischemia in rats by Dreixler, John C, Poston, Jacqueline N, Balyasnikova, Irina, Shaikh, Afzhal R, Tupper, Kelsey Y, Conway, Sineadh, Boddapati, Venkat, Marcet, Marcus M, Lesniak, Maciej S, Roth, Steven

“…Delayed treatment after ischemia is often unsatisfactory. We hypothesized that injection of bone marrow stem cell (BMSC) conditioned medium after ischemia…”
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Post-ischemic conditioning in the rat retina is dependent upon ischemia duration and is not additive with ischemic pre-conditioning by Dreixler, John C., Shaikh, Afzhal R., Alexander, Michael, Savoie, Brian, Roth, Steven

“…Ischemic pre-conditioning (IPC) provides neuroprotection in the rat retina from the damaging effects of severe ischemia. Recently, neuroprotection by retinal…”
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Mitochondrial Potassium ATP Channels and Retinal Ischemic Preconditioning by Roth, Steven, Dreixler, John C, Shaikh, Afzhal R, Lee, Katherine H, Bindokas, Vytautus

“…To examine the mechanisms of ischemic preconditioning (IPC) related to the opening of mitochondrial KATP (mKATP) channels in the retina. Rats were subjected to…”
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Block of rat brain recombinant SK channels by tricyclic antidepressants and related compounds by Dreixler, John C, Bian, Jing-Tan, Cao, Ying-Jun, Roberts, Michael T, Roizen, Jeffrey D, Houamed, Khaled M

“…SK channels are small conductance, Ca 2+-activated K + channels that underlie neuronal slow afterhyperpolarization and mediate spike frequency adaptation…”
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Delayed post-ischemic conditioning significantly improves the outcome after retinal ischemia by Dreixler, John C., Poston, Jacqueline N., Shaikh, Afzhal R., Alexander, Michael, Tupper, Kelsey Y., Marcet, Marcus M., Bernaudin, Myriam, Roth, Steven

“…In previous studies, it was shown that post-conditioning, a transient period of brief ischemia following prolonged severe ischemia in the retina, could provide…”
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The role of Akt/protein kinase B subtypes in retinal ischemic preconditioning by Dreixler, John C., Hemmert, Jonathan W., Shenoy, Shanti K., Shen, Yang, Lee, H. Thomas, Shaikh, Afzhal R., Rosenbaum, Daniel M., Roth, Steven

“…Potent endogenous protection from ischemia can be induced in the retina by ischemic preconditioning (IPC). Protein kinase B/Akt is a cellular survival factor…”
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Protein Kinase B (Akt) and Mitogen-Activated Protein Kinase p38α in Retinal Ischemic Post-Conditioning by Dreixler, John C., Sampat, Ajay, Shaikh, Afzhal R., Alexander, Michael, Marcet, Marcus M., Roth, Steven

“…In previous studies, it was shown that post-conditioning, a transient period of brief ischemia following prolonged severe ischemia in the retina, could provide…”
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Protein kinase C subtypes and retinal ischemic preconditioning by Dreixler, John C., Shaikh, Afzhal R., Shenoy, Shanti K., Shen, Yang, Roth, Steven

“…The purpose of our study was to determine the specific subtypes of protein kinase C involved in the neuroprotection afforded by retinal ischemic…”
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Giant excised patch recordings of recombinant ion channel currents expressed in mammalian cells by Couey, Jonathan J., Ryan, Devon P., Glover, John T., Dreixler, John C., Young, Joseph B., Houamed, Khaled M.

“…The giant excised patch variant of patch clamp recording combines microsecond time resolution of macroscopic currents with rapid exchange of the experimental…”
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Mitogen-activated protein kinase p38α and retinal ischemic preconditioning by Dreixler, John C., Barone, Frank C., Shaikh, Afzhal R., Du, Eugenie, Roth, Steven

“…In previous studies, inhibition of mitogen-activated protein kinase (MAP) p38 significantly improved recovery and attenuated apoptosis after retinal ischemia…”
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Protein Kinase B (Akt) and Mitogen-Activated Protein Kinase p38[alpha] in Retinal Ischemic Post-Conditioning by Dreixler, John C, Sampat, Ajay, Shaikh, Afzhal R, Alexander, Michael, Marcet, Marcus M, Roth, Steven

“…In previous studies, it was shown that post-conditioning, a transient period of brief ischemia following prolonged severe ischemia in the retina, could provide…”
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Post-ischemic Conditioning in the Rat Retina is Dependent Upon Ischemia Duration and is not Additive with Ischemic Preconditioning by Dreixler, John C., Shaikh, Afzhal R., Alexander, Michael, Savoie, Brian, Roth, Steven

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Mitogen-activated protein kinase p38alpha and retinal ischemic preconditioning by Dreixler, John C, Barone, Frank C, Shaikh, Afzhal R, Du, Eugenie, Roth, Steven

“…In previous studies, inhibition of mitogen-activated protein kinase (MAP) p38 significantly improved recovery and attenuated apoptosis after retinal ischemia…”
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Patch-clamp analysis of anesthetic interactions with recombinant SK2 subtype neuronal calcium-activated potassium channels by DREIXLER, J. C, JENKINS, A, CAO, Y.-J, ROIZEN, J. D, HOUAMED, K. M

“…Small conductance calcium-activated potassium channels (SK) mediate spike frequency adaptation and underlie the slow afterhyperpolarization in central neurons…”
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Room F, 10/16/2000 9: 00 AM - 11: 00 AM (PS) A Molecular Mechanism for Action of Neuroprotectants and Paralytic Drugs by Cao, Ying-Jun, Dreixler, John C., Roizen, Jeffrey D., Roberts, Michael T., Houamed, Khaled M.

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