Search Results - "Dreger, Stefanie C."
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Clostridium difficile toxins: More than mere inhibitors of Rho proteins
Published in The international journal of biochemistry & cell biology (2008)“…Toxin A (TcdA) and Toxin B (TcdB) are the major pathogenicity factors of the Clostridium difficile-associated diarrhoea (CDAD). The single-chained protein…”
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Killing of Rat Basophilic Leukemia Cells by Lethal Toxin from Clostridium sordellii: Critical Role of Phosphatidylinositide 3′-OH Kinase/Akt Signaling
Published in Biochemistry (Easton) (03-03-2009)“…Clostridium sordellii lethal toxin (TcsL) belongs to the family of clostridial glucosylating toxins. TcsL exhibits glucosyltransferase activity to inactivate…”
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29-amino acid fragment of Clostridium botulinum C3 protein enhances neuronal outgrowth, connectivity, and reinnervation
Published in The FASEB journal (01-04-2009)“…Small GTPases of the Rho family play versatile roles in the formation and development of axons and dendrites, effects often studied by the Rho-inactivating C3…”
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Upregulation of the Immediate Early Gene Product RhoB by Exoenzyme C3 from Clostridium limosum and Toxin B from Clostridium difficile
Published in Biochemistry (Easton) (24-04-2007)“…ADP-ribosylation of Rho(A,B,C) by the family of exoenzyme C3-like transferases induces reorganization of the actin cytoskeleton based on inactivation of RhoA…”
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