Search Results - "Drees, Steffen L"
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Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer
Published in Nature communications (25-05-2020)“…Light-dependent or light-stimulated catalysis provides a multitude of perspectives for implementation in technological or biomedical applications. Despite…”
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2
Substrate Inhibition of 5β-Δ4-3-Ketosteroid Dehydrogenase in Sphingobium sp. Strain Chol11 Acts as Circuit Breaker During Growth With Toxic Bile Salts
Published in Frontiers in microbiology (23-03-2021)“…In contrast to many steroid hormones and cholesterol, mammalian bile salts are 5β-steroids, which leads to a bent structure of the steroid core. Bile salts are…”
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3
Signal Synthase-Type versus Catabolic Monooxygenases: Retracing 3-Hydroxylation of 2-Alkylquinolones and Their N -Oxides by Pseudomonas aeruginosa and Other Pulmonary Pathogens
Published in Applied and environmental microbiology (26-02-2021)“…The multiple biological activities of 2-alkylquinolones (AQs) are crucial for virulence of , conferring advantages during infection and in polymicrobial…”
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4
A Complex of LaoA and LaoB Acts as a Tat-Dependent Dehydrogenase for Long-Chain Alcohols in Pseudomonas aeruginosa
Published in Applied and environmental microbiology (27-07-2021)“…The opportunistic pathogen Pseudomonas aeruginosa can utilize unusual carbon sources, like sodium dodecyl sulfate (SDS) and alkanes. Whereas the initiating…”
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5
Erratum for Ritzmann et al., “Signal Synthase-Type versus Catabolic Monooxygenases: Retracing 3-Hydroxylation of 2-Alkylquinolones and Their N-Oxides by Pseudomonas aeruginosa and Other Pulmonary Pathogens”
Published in Applied and environmental microbiology (11-08-2021)Get full text
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6
A comparative study of N‐hydroxylating flavoprotein monooxygenases reveals differences in kinetics and cofactor binding
Published in The FEBS journal (01-09-2022)“…Many natural products comprise N‐O containing functional groups with crucial roles for biological activity. Their enzymatic formation is predominantly achieved…”
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7
FTIR spectroscopy of biofluids revisited: an automated approach to spectral biomarker identification
Published in Analyst (London) (21-07-2013)“…The extraction of disease specific information from Fourier transform infrared (FTIR) spectra of human body fluids demands the highest standards of accuracy…”
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8
Bromination of alkyl quinolones by Microbulbifer sp. HZ11, a marine Gammaproteobacterium, modulates their antibacterial activity
Published in Environmental microbiology (01-07-2019)“…Summary Alkyl quinolones (AQs) are multifunctional bacterial secondary metabolites generally known for their antibacterial and algicidal properties. Certain…”
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9
One gene, two proteins: coordinated production of a copper chaperone by differential transcript formation and translational frameshifting in Escherichia coli
Published in Molecular microbiology (01-11-2017)“…Summary Programmed ribosomal frameshifting (PRF) is a translational anomaly causing the ribosome to shift into an alternative reading frame. PRFs are common in…”
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10
Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds
Published in ACS chemical biology (17-06-2016)“…Pseudomonas aeruginosa uses quorum sensing (QS) as a cell-to-cell communication system to orchestrate the expression of virulence determinants. The…”
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11
Interference with Pseudomonas aeruginosa Quorum Sensing and Virulence by the Mycobacterial Pseudomonas Quinolone Signal Dioxygenase AqdC in Combination with the N -Acylhomoserine Lactone Lactonase QsdA
Published in Infection and immunity (01-10-2019)“…The nosocomial pathogen regulates its virulence via a complex quorum sensing network, which, besides -acylhomoserine lactones, includes the alkylquinolone…”
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12
Polypharmacology Approaches against the Pseudomonas aeruginosa MvfR Regulon and Their Application in Blocking Virulence and Antibiotic Tolerance
Published in ACS chemical biology (19-05-2017)“…Pseudomonas aeruginosa is an important nosocomial pathogen that is frequently recalcitrant to available antibiotics, underlining the urgent need for…”
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13
The ATPases CopA and CopB both contribute to copper resistance of the thermoacidophilic archaeon Sulfolobus solfataricus
Published in Microbiology (Society for General Microbiology) (01-06-2012)“…Certain heavy metal ions such as copper and zinc serve as essential cofactors of many enzymes, but are toxic at high concentrations. Thus, intracellular levels…”
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14
Old Molecules, New Biochemistry
Published in Chemistry & biology (19-12-2013)“…The study by Dulcey and colleagues in this issue of Chemistry & Biology changes our perception of the pathway of 2-alkyl-4-hydroxyquinoline biosynthesis by the…”
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15
Substrate Inhibition of 5β-Δ 4 -3-Ketosteroid Dehydrogenase in Sphingobium sp. Strain Chol11 Acts as Circuit Breaker During Growth With Toxic Bile Salts
Published in Frontiers in microbiology (2021)“…In contrast to many steroid hormones and cholesterol, mammalian bile salts are 5β-steroids, which leads to a bent structure of the steroid core. Bile salts are…”
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16
One gene, two proteins: coordinated production of a copper chaperone by differential transcript formation andᅡ translational frameshifting in Escherichia coli
Published in Molecular microbiology (01-11-2017)“…Summary Programmed ribosomal frameshifting (PRF) is a translational anomaly causing the ribosome to shift into an alternative reading frame. PRFs are common in…”
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17
Distinct functions of serial metal-binding domains in the Escherichia coli P^sub 1B^-ATPase CopA
Published in Molecular microbiology (01-08-2015)“…P1B-ATPases are among the most common resistance factors to metal-induced stress. Belonging to the superfamily of P-type ATPases, they are capable of exporting…”
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18
Distinct functions of serial metal‐binding domains in the Escherichia coli P1B‐ATPase CopA
Published in Molecular microbiology (01-08-2015)“…Summary P1B‐ATPases are among the most common resistance factors to metal‐induced stress. Belonging to the superfamily of P‐type ATPases, they are capable of…”
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Distinct functions of serial metal‐binding domains in the E scherichia coli P 1 B ‐ ATP ase CopA
Published in Molecular microbiology (01-08-2015)“…Summary P 1 B ‐ ATP ases are among the most common resistance factors to metal‐induced stress. Belonging to the superfamily of P ‐type ATP ases, they are…”
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20
Distinct functions of serial metal-binding domains in the Escherichia coli P1 B -ATPase CopA
Published in Molecular microbiology (01-08-2015)“…P1 B -ATPases are among the most common resistance factors to metal-induced stress. Belonging to the superfamily of P-type ATPases, they are capable of…”
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