Search Results - "Dray, C."

The therapeutic potentials of apelin in obesity-associated diseases by Castan-Laurell, I., Dray, C., Valet, P.

“…Apelin, a peptide with several active isoforms ranging from 36 to 12 amino acids and its receptor APJ, a G-protein-coupled receptor, are widely distributed…”
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Effect of endurance training on skeletal muscle myokine expression in obese men: identification of apelin as a novel myokine by Besse-Patin, A, Montastier, E, Vinel, C, Castan-Laurell, I, Louche, K, Dray, C, Daviaud, D, Mir, L, Marques, M-A, Thalamas, C, Valet, P, Langin, D, Moro, C, Viguerie, N

“…Background: It has been suggested that the metabolic benefits of physical exercise could be mediated by myokines. We examined here the effect of exercise…”
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Apelin receptors: From signaling to antidiabetic strategy by Chaves-Almagro, C., Castan-Laurell, I., Dray, C., Knauf, C., Valet, P., Masri, B.

“…The G protein-coupled receptor APJ and its cognate ligand, apelin, are widely expressed throughout human body. They are implicated in different key…”
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Revisiting the Hallmarks of Aging to Identify Markers of Biological Age by Guerville, Florent, De Souto Barreto, P., Ader, I., Andrieu, S., Casteilla, L., Dray, C., Fazilleau, N., Guyonnet, S., Langin, D., Liblau, R., Parini, A., Valet, P., Vergnolle, N., Rolland, Y., Vellas, B.

“…The Geroscience aims at a better understanding of the biological processes of aging, to prevent and/or delay the onset of chronic diseases and disability as…”
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Apelin controls emotional behavior in age- and metabolic state-dependent manner by Bullich, S., de Souto Barreto, P., Dortignac, A., He, L., Dray, C., Valet, P., Guiard, BP

“…Apelin is a small peptide secreted by the adipose tissue notably in conditions of obesity-induced hyper-insulinemia. Apelin exerts a range of physiological…”
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A gerophysiology perspective on healthy ageing by Kemoun, Ph, Ader, I., Planat-Benard, V., Dray, C., Fazilleau, N., Monsarrat, P., Cousin, B., Paupert, J., Ousset, M., Lorsignol, A., Raymond-Letron, I., Vellas, B., Valet, P., Kirkwood, T., Beard, J., Pénicaud, L., Casteilla, L.

“…Improvements in public health and health care have resulted in significant increases in lifespan globally, but also in a significant increase in chronic…”
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Circulating Levels of Apelin, GDF-15 and Sarcopenia: Lack of Association in the MAPT Study by Sanchez-Sánchez, Juan Luis, He, L., Virecoulon Giudici, K., Guyonnet, S., Parini, A., Dray, C., Valet, P., Pereira, O., Vellas, B., Rolland, Y., de Souto Barreto, P.

“…Objectives Apelin and GDF-15 have been proposed as biomarkers of age-related sarcopenia but evidence in human models is scarce. This study aimed to explore the…”
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Apelin stimulates glucose uptake but not lipolysis in human adipose tissue ex vivo by Attané, C, Daviaud, D, Dray, C, Dusaulcy, R, Masseboeuf, M, Prévot, D, Carpéné, C, Castan-Laurell, I, Valet, P

“…Apelin is a peptide present in different cell types and secreted by adipocytes in humans and rodents. Apelin exerts its effects through a G-protein-coupled…”
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Response to Elia et al. 'Tauroursodeoxycholic acid in the treatment of patients with amyotrophic lateral sclerosis' by Michaud, M., Gauchet, C., Dray, C.

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The INSPIRE Research Initiative: A Program for GeroScience and Healthy Aging Research Going from Animal Models to Humans and the Healthcare System by de Souto Barreto, P, Guyonnet, S, Ader, I, Andrieu, S, Casteilla, L, Davezac, N, Dray, C, Fazilleau, N, Gourdy, P, Liblau, R, Parini, A, Payoux, P, Pénicaud, L, Rampon, C, Rolland, Y, Valet, P, Vergnolle, N, Vellas, B

“…Aging is the most important risk factor for the onset of several chronic diseases and functional decline. Understanding the interplays between biological aging…”
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Apelin/APJ signaling system: a potential link between adipose tissue and endothelial angiogenic processes by Kunduzova, O, Alet, N, Delesque-Touchard, N, Millet, L, Castan-Laurell, I, Muller, C, Dray, C, Schaeffer, P, Herault, J.P, Savi, P, Bono, F, Valet, P

“…Adipose tissue is an active endocrine organ that produces a variety of secretory factors involved in the initiation of angiogenic processes. The bioactive…”
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Expanding role for the apelin/APJ system in physiopathology by Carpéné, C, Dray, C, Attané, C, Valet, P, Portillo, M P, Churruca, I, Milagro, F I, Castan-Laurell, I

“…Apelin is a bioactive peptide known as the ligand of the G protein-coupled receptor APJ. Diverse active apelin peptides exist under the form of 13, 17 or 36…”
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The INSPIRE Bio-Resource Research Platform for Healthy Aging and Geroscience: Focus on the Human Translational Research Cohort (The INSPIRE-T Cohort) by Guyonnet, S, Rolland, Y, Takeda, C, Ousset, P-J, Ader, I, Davezac, N, Dray, C, Fazilleau, N, Gourdy, P, Liblau, R, Parini, A, Payoux, P, Pénicaud, L, Rampon, C, Valet, P, Vergnolle, N, Andrieu, S, de Souto Barreto, P, Casteilla, L, Vellas, B

“…The Geroscience field focuses on the core biological mechanisms of aging, which are involved in the onset of age-related diseases, as well as declines in…”
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Aeroaging — A new collaboration between life sciences experts and aerospace engineers by Vellas, M., Fualdes, C., Morley, J. E., Dray, C., Rodriguez-Manas, L., Meyer, A., Michel, L., Rolland, Y., Gourinat, Y.

“…An open discussion between experts from life sciences and aeronautics has been held in order to investigate how both area of research overlap and could be…”
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Healthy Aging Biomarkers: The INSPIRE's Contribution by Ader, I, Pénicaud, L, Andrieu, S, Beard, J R, Davezac, N, Dray, C, Fazilleau, N, Gourdy, P, Guyonnet, S, Liblau, R, Parini, A, Payoux, P, Rampon, C, Raymond-Letron, I, Rolland, Y, de Souto Barreto, P, Valet, P, Vergnolle, N, Sierra, F, Vellas, B, Casteilla, L

“…The find solutions for optimizing healthy aging and increase health span is one of the main challenges for our society. A novel healthcare model based on…”
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Highlights from the 2019 International Congress on Frailty and Sarcopenia Research by Maltais, M, Aubertin-Leheudre, M, Dray, C, Fielding, R A, Rolland, Y, Cesari, M, Vellas, B

“…[...]these updates regarding sarcopenia’s classification of a disease and its new definition reiterates critical role in the development of dependence in older…”
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Caffeine reduces TNFα up-regulation in human adipose tissue primary culture by Dray, C., Daviaud, D., Guigné, C., Valet, P., Castan-Laurell, I.

“…Adipose tissue secretions play an important role in the development of obesityrelated pathologies such as diabetes. Through inflammatory cytokines production,…”
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P168 Augmentation par les lipopolysaccharides de la sécrétion d’insuline stimulée par le glucose : Implication de la voie du Glucagon Like Peptide-1 (GLP-1) by Grober, J, Nguyen, A, Mandard, S, Dray, C, Deckert, V, Valet, P, Besnard, P, Drucker, D, Lagrost, L

“…Introduction L’obésité est devenue la première maladie non infectieuse de l’histoire. Elle peut être associée à d’autres pathologies constituant le syndrome…”
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Native fructose extracted from apple improves glucose tolerance in mice by Dray, C., Colom, A., Guigné, C., Legonidec, S., Guibert, A., Ouarne, F., Valet, P.

“…Fructose is one of the most abundant monosaccharide in nature. It is also the sweetest naturally occurring carbohydrate. Since decades, fructose used for food…”
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Quantitative analysis by in vivo imaging of the dynamics of vascular and axonal networks in injured mouse spinal cord by Dray, Cyril, Rougon, Geneviève, Debarbieux, Franck

“…Understanding the endogenous repair capacity of spinal cord is pivotal to develop strategies to improve it. Here we design a paradigm of spinal cord lesion in…”
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