Search Results - "Dravolina, Olga A."

Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats by Bespalov, Anton Y., Dravolina, Olga A., Sukhanov, Ilya, Zakharova, Elena, Blokhina, Elena, Zvartau, Edwin, Danysz, Wojciech, van Heeke, Gino, Markou, Athina

“…Previous studies suggested that metabotropic glutamate 5 (mGlu5) receptors play an important role in the reinforcing effects of abused drugs. The present…”
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Study of aversive and p38 mapk-inhibitory properties of kappa-agonist with analgesic activity – compound RU-1205 by Spasov, Alexander A., Zvartau, Edwin E., Grechko, Olesya Iu, Eliseeva, Natalya V., Semenova, Yuliya V., Dravolina, Olga A., Vasiliev, Pavel M., Anisimova, Vera A.

“…Introduction: The clinical use of kappa-opioid agonists, despite their lack of significant drug potential, is limited by the development of severe sedation,…”
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Efficacy and side effects of baclofen and the novel GABA B receptor positive allosteric modulator CMPPE in animal models for alcohol and cocaine addiction by Vengeliene, Valentina, Takahashi, Tatiane T, Dravolina, Olga A, Belozertseva, Irina, Zvartau, Edwin, Bespalov, Anton Y, Spanagel, Rainer

“…Preclinical studies suggest that the GABA receptor is a potential target for treatment of substance use disorders. However, recent clinical trials report…”
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mGlu1 receptor as a drug target for treatment of substance use disorders: time to gather stones together? by Dravolina, Olga A., Zvartau, Edwin, Danysz, Wojciech, Bespalov, Anton Y.

“…Modulation of the mGlu1 receptor was repeatedly shown to inhibit various phenomena associated with exposure to abused drugs. Efficacy in preclinical models was…”
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Agonist and antagonist effects of cytisine in vivo by Radchenko, Elena V., Dravolina, Olga A., Bespalov, Anton Y.

“…Varenicline, the most successful smoking cessation aid, is a selective partial agonists at α4β2* nicotinic receptors. Its efficacy is likely to be shared by…”
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Efficacy and side effects of baclofen and the novel GABAB receptor positive allosteric modulator CMPPE in animal models for alcohol and cocaine addiction by Vengeliene, Valentina, Takahashi, Tatiane T., Dravolina, Olga A., Belozertseva, Irina, Zvartau, Edwin, Bespalov, Anton Y., Spanagel, Rainer

“…Rationale Preclinical studies suggest that the GABA B receptor is a potential target for treatment of substance use disorders. However, recent clinical trials…”
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Morphine-induced Straub tail reaction in mice treated with serotonergic compounds by Belozertseva, Irina V., Dravolina, Olga A., Tur, Margarita A., Semina, Marina G., Zvartau, Edwin E., Bespalov, Anton Yu

“…Constitutively active 5-HT2 receptors have been suggested to contribute to motoneuronal excitability, muscle spasms and spasticity. Accordingly, 5-HT2C…”
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mGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats by Dravolina, Olga A., Zakharova, Elena S., Shekunova, Elena V., Zvartau, Edwin E., Danysz, Wojciech, Bespalov, Anton Y.

“…Glutamatergic neurotransmission is believed to be critically involved in the acquisition and maintenance of drug addiction. The present study evaluated the…”
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Effects of group I metabotropic glutamate receptor antagonists on the behavioral sensitization to motor effects of cocaine in rats by DRAVOLINA, Olga A, DANYSZ, Wojciech, BESPALOV, Anton Y

“…Metabotropic glutamate receptors (mGluRs) were reported to regulate various behavioral effects of addictive drugs. The present study evaluated the role of…”
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Antinociceptive activity of combination of morphine and NMDA receptor antagonists depends on the inter-injection interval by Belozertseva, Irina V, Dravolina, Olga A, Neznanova, Olga N, Danysz, Wojciech, Bespalov, Anton Y

“…The actual time-course of morphine antinociception is shorter than what would be predicted from its elimination kinetics, suggesting the presence of an acute…”
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Effects of mGlu1 receptor blockade on working memory, time estimation, and impulsivity in rats by Sukhotina, Irina A., Dravolina, Olga A., Novitskaya, Yulia, Zvartau, Edwin E., Danysz, Wojciech, Bespalov, Anton Y.

“…Rationale Metabotropic glutamate 1 (mGlu1) receptor antagonists were reported to induce cognitive deficits in several animal models using aversive learning…”
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Intravenous self-administration of abused solvents and anesthetics in mice by Blokhina, Elena A, Dravolina, Olga A, Bespalov, Anton Y, Balster, Robert L, Zvartau, Edwin E

“…Volatile organic solvents, fuels and anesthetics are subject to abuse. The aim of the present study was to evaluate i.v. self-administration of several of…”
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Effects of NMDA receptor antagonists on cocaine-conditioned motor activity in rats by Bespalov, Anton Y, Dravolina, Olga A, Zvartau, Edwin E, Beardsley, Patrick M, Balster, Robert L

“…NMDA receptor antagonists have been reported to affect learned behaviors conditioned with abused drugs, with the outcome dependent, in part, on the class of…”
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Effects of N-methyl-D-aspartate receptor antagonists on discriminative stimulus effects of naloxone in morphine-dependent rats using the Y-maze drug discrimination paradigm by Medvedev, I O, Dravolina, O A, Bespalov, A Y

“…The present study assessed the ability of various site-selective N-methyl-D-aspartate (NMDA) receptor antagonists to affect the discriminative stimulus…”
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Efficacy and side effects of baclofen and the novel GABA.sub.B receptor positive allosteric modulator CMPPE in animal models for alcohol and cocaine addiction by Vengeliene, Valentina, Takahashi, Tatiane T, Dravolina, Olga A, Belozertseva, Irina, Zvartau, Edwin, Bespalov, Anton Y, Spanagel, Rainer

“…Rationale Preclinical studies suggest that the GABA.sub.B receptor is a potential target for treatment of substance use disorders. However, recent clinical…”
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Differential effects of nitric oxide synthase inhibitor, 7-nitroindazole, on discriminative stimulus and somatic effects of naloxone in morphine-dependent rats by Medvedev, Ivan O, Dravolina, Olga A, Bespalov, Anton Y

“…Our previous report suggested that antagonists acting at NMDA receptors attenuate discriminative stimulus effects of naloxone in morphine dependent rats…”
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Morphine Tolerance and Dependence in Mice with History of Repeated Exposures to NMDA Receptor Channel Blockers by Dravolina, Olga A, Belozertseva, Irina V, Sukhotina, Irina A, Bespalov, Anton Y

“…Mice were subjected to two successive treatment protocols: first with NMDA receptor channel blockers (14 days, once a day) and second with morphine (5 mg/kg, 8…”
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Effects of Calcium Channel Blockers on Behaviors Induced by the N-Methyl- d-Aspartate Receptor Antagonist, Dizocilpine, in Rats by Sukhotina, Irina A, Dravolina, Olga A, Medvedev, Ivan O, Bespalov, Anton Yu

“…The present study assessed the ability of voltage-sensitive calcium channel (VSCC) blockers to affect the behavioral effects of the noncompetitive N-methyl-…”
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Decrement in Operant Performance Produced by NMDA Receptor Antagonists in the Rat: Tolerance and Crosstolerance by Dravolina, Olga A, Zvartau, Edwin E, Bespalov, Anton Y

“…Current perspectives on the clinical use of NMDA receptor antagonists infer repeated administration schedules for the management of different pathological…”
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Effects of mGlul receptor blockade on working memory, time estimation, and impulsivity in rats by SUKHOTINA, Irina A, DRAVOLINA, Olga A, NOVITSKAYA, Yulia, ZVARTAU, Edwin E, DANYSZ, Wojciech, BESPALOV, Anton Y

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