Search Results - "Draper, S. J."

Comparative Assessment of Transmission-Blocking Vaccine Candidates against Plasmodium falciparum by Kapulu, M. C., Da, D. F., Miura, K., Li, Y, Blagborough, A. M., Churcher, T. S., Nikolaeva, D., Williams, A. R., Goodman, A. L., Sangare, I., Turner, A. V., Cottingham, M. G., Nicosia, A., Straschil, U., Tsuboi, T., Gilbert, S. C., Long, Carole A., Sinden, R. E., Draper, S. J., Hill, A. V. S., Cohuet, A., Biswas, S.

“…Malaria transmission-blocking vaccines (TBVs) target the development of Plasmodium parasites within the mosquito, with the aim of preventing malaria…”
Get full text

Preimplantation Human Embryos and Embryonic Stem Cells Show Comparable Expression of Stage‐Specific Embryonic Antigens by Henderson, J. K., Draper, J. S., Baillie, H. S., Fishel, S., Thomson, J. A., Moore, H., Andrews, P. W.

“…Cell‐surface antigens provide invaluable tools for the identification of cells and for the analysis of cell differentiation. In particular, stage‐specific…”
Get full text

Substantially Reduced Pre-patent Parasite Multiplication Rates Are Associated With Naturally Acquired Immunity to "Plasmodium falciparum" by Douglas, A. D., Andrews, L., Draper, S. J., Bojang, K., Milligan, P., Gilbert, S. C., Imoukhuede, E. B., Hill, A. V. S.

“…Naturally acquired immunity to Plasmodium falciparum's asexual blood stage reduces parasite multiplication at microscopically detectable densities. The effect…”
Get full text

New Candidate Vaccines against Blood-Stage Plasmodium falciparum Malaria: Prime-Boost Immunization Regimens Incorporating Human and Simian Adenoviral Vectors and Poxviral Vectors Expressing an Optimized Antigen Based on Merozoite Surface Protein 1 by Goodman, Anna L, Epp, C, Moss, D, Holder, A.A, Wilson, J.M, Gao, G.P, Long, C.A, Remarque, E.J, Thomas, A.W, Ammendola, V, Colloca, S, Dicks, M.D.J, Biswas, S, Seibel, D, van Duivenvoorde, L.M, Gilbert, S.C, Hill, A.V.S, Draper, S.J

“…Although merozoite surface protein 1 (MSP-1) is a leading candidate vaccine antigen for blood-stage malaria, its efficacy in clinical trials has been limited…”
Get full text

Single-Dose Protection against Plasmodium berghei by a Simian Adenovirus Vector Using a Human Cytomegalovirus Promoter Containing Intron A by SRIDHAR, S, REYES-SANDOVAL, A, DRAPER, S. J, MOORE, A. C, GILBERT, S. C, GAO, G. P, WILSON, J. M, HILL, A. V. S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Trophic Action of Leptin on Hypothalamic Neurons That Regulate Feeding by Bouret, Sebastien G., Draper, Shin J., Simerly, Richard B.

“…In adult mammals, the adipocyte-derived hormone leptin acts on the brain to reduce food intake by regulating the activity of neurons in the arcuate nucleus of…”
Get full text

Quantifying intrinsic and extrinsic control of single-cell fates in cancer and stem/progenitor cell pedigrees with competing risks analysis by Cornwell, J. A., Hallett, R. M., der Mauer, S. Auf, Motazedian, A., Schroeder, T., Draper, J. S., Harvey, R. P., Nordon, R. E.

“…The molecular control of cell fate and behaviour is a central theme in biology. Inherent heterogeneity within cell populations requires that control of cell…”
Get full text

Blood-stage malaria vaccines - recent progress and future challenges by Goodman, A. L., Draper, S. J.

“…Plasmodium falciparum malaria is a major global health problem, responsible for up to 1 million deaths each year. Major efforts have been made to develop an…”
Get full text

Formation of Projection Pathways from the Arcuate Nucleus of the Hypothalamus to Hypothalamic Regions Implicated in the Neural Control of Feeding Behavior in Mice by Bouret, Sebastien G, Draper, Shin J, Simerly, Richard B

“…The arcuate nucleus of the hypothalamus (ARH) is a critical component of forebrain pathways that regulate a variety of neuroendocrine functions, including an…”
Get full text

Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells by Andrews, Peter W, Draper, Jonathan S, Smith, Kath, Gokhale, Paul, Moore, Harry D, Maltby, Edna, Johnson, Julie, Meisner, Lorraine, Zwaka, Thomas P, Thomson, James A

“…We have observed karyotypic changes involving the gain of chromosome 17q in three independent human embryonic stem (hES) cell lines on five independent…”
Get full text

Gene Expression Patterns in Human Embryonic Stem Cells and Human Pluripotent Germ Cell Tumors by Sperger, Jamie M., Chen, Xin, Draper, Jonathan S., Antosiewicz, Jessica E., Chon, Chris H., Jones, Sunita B., Brooks, James D., Andrews, Peter W., Brown, Patrick O., Thomson, James A.

“…Remarkably little is known about the transcriptional profiles of human embryonic stem (ES) cells or the molecular mechanisms that underlie their pluripotency…”
Get full text

Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin by Andrews, P W, Matin, M M, Bahrami, A R, Damjanov, I, Gokhale, P, Draper, J S

“…Embryonal carcinoma (EC) cells are the stem cells of teratocarcinomas, and the malignant counterparts of embryonic stem (ES) cells derived from the inner cell…”
Get more information

Utilizing poxviral vectored vaccines for antibody induction—Progress and prospects by Draper, Simon J, Cottingham, Matthew G, Gilbert, Sarah C

“…Highlights • Poxviral vectors are now regarded as robust tools for B cell and antibody induction. • Antibody responses can be induced against the vector as…”
Get full text

TrackPad: Software for semi-automated single-cell tracking and lineage annotation by Cornwell, J.A., Li, J., Mahadevan, S., Draper, J.S., Joun, G.L., Zoellner, H., Asli, N.S., Harvey, R.P., Nordon, R.E.

“…TrackPad is an open-source, biologist-friendly, graphical user interface for tracking and annotating single-cell lineage fates from time-lapse movies. The…”
Get full text

Synergistic blockade of TIGIT and PD-L1 increases type-1 inflammation and improves parasite control during murine blood-stage Plasmodium yoelii non-lethal infection by Dookie, Rebecca S, Villegas-Mendez, Ana, Cheeseman, Antonn, Jones, Adam P, Barroso, Ruben, Barrett, Jordan R, Draper, Simon J, Janse, Chris J, Grogan, Jane L, MacDonald, Andrew S, Couper, Kevin N

“…Pro-inflammatory immune responses are rapidly suppressed during blood-stage malaria but the molecular mechanisms driving this regulation are still incompletely…”
Get full text

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative by Adewumi, Oluseun, Aflatoonian, Behrouz, Ahrlund-Richter, Lars, Amit, Michal, Andrews, Peter W, Beighton, Gemma, Bello, Paul A, Benvenisty, Nissim, Berry, Lorraine S, Bevan, Simon, Blum, Barak, Brooking, Justin, Chen, Kevin G, Choo, Andre B H, Churchill, Gary A, Corbel, Marie, Damjanov, Ivan, Draper, Jon S, Dvorak, Petr, Emanuelsson, Katarina, Fleck, Roland A, Ford, Angela, Gertow, Karin, Gertsenstein, Marina, Gokhale, Paul J, Hamilton, Rebecca S, Hampl, Ales, Healy, Lyn E, Hovatta, Outi, Hyllner, Johan, Imreh, Marta P, Itskovitz-Eldor, Joseph, Jackson, Jamie, Johnson, Jacqueline L, Jones, Mark, Kee, Kehkooi, King, Benjamin L, Knowles, Barbara B, Lako, Majlinda, Lebrin, Franck, Mallon, Barbara S, Manning, Daisy, Mayshar, Yoav, McKay, Ronald D G, Michalska, Anna E, Mikkola, Milla, Mileikovsky, Masha, Minger, Stephen L, Moore, Harry D, Mummery, Christine L, Nagy, Andras, Nakatsuji, Norio, O'Brien, Carmel M, Oh, Steve K W, Olsson, Cia, Otonkoski, Timo, Park, Kye-Yoon, Passier, Robert, Patel, Hema, Patel, Minal, Pedersen, Roger, Pera, Martin F, Piekarczyk, Marian S, Pera, Renee A Reijo, Reubinoff, Benjamin E, Robins, Allan J, Rossant, Janet, Rugg-Gunn, Peter, Schulz, Thomas C, Semb, Henrik, Sherrer, Eric S, Siemen, Henrike, Stacey, Glyn N, Stojkovic, Miodrag, Suemori, Hirofumi, Szatkiewicz, Jin, Turetsky, Tikva, Tuuri, Timo, van den Brink, Steineke, Vintersten, Kristina, Vuoristo, Sanna, Ward, Dorien, Weaver, Thomas A, Young, Lesley A, Zhang, Weidong

“…The International Stem Cell Initiative characterized 59 human embryonic stem cell lines from 17 laboratories worldwide. Despite diverse genotypes and different…”
Get full text

Improved embryonic stem cell technologies by Draper, J S, Nagy, A

“…Murine embryonic stem (ES) cells have become an indispensable tool for investigating genetic function both in vitro and, importantly, in vivo. Recent advances,…”
Get more information

Targets and Mechanisms Associated with Protection from Severe Plasmodium falciparum Malaria in Kenyan Children by Murungi, Linda M, Sondén, Klara, Llewellyn, David, Rono, Josea, Guleid, Fatuma, Williams, Andrew R, Ogada, Edna, Thairu, Amos, Färnert, Anna, Marsh, Kevin, Draper, Simon J, Osier, Faith H A

“…Severe malaria (SM) is a life-threatening complication of infection with Plasmodium falciparum Epidemiological observations have long indicated that immunity…”
Get full text

New Candidate Vaccines against Blood-Stage Plasmodium falciparum Malaria: Prime-Boost Immunization Regimens Incorporating Human and Simian Adenoviral Vectors and Poxviral Vectors Expressing an Optimized Antigen Based on Merozoite Surface Protein 1 by Goodman, Anna L., Epp, C., Moss, D., Holder, A. A., Wilson, J. M., Gao, G. P., Long, C. A., Remarque, E. J., Thomas, A. W., Ammendola, V., Colloca, S., Dicks, M. D. J., Biswas, S., Seibel, D., van Duivenvoorde, L. M., Gilbert, S. C., Hill, A. V. S., Draper, S. J.

Get full text

Specific Knockdown of Oct4 and beta 2-microglobulin Expression by RNA Interference in Human Embryonic Stem Cells and Embryonic Carcinoma Cells by Matin, Maryam M, Walsh, James R, Gokhale, Paul J, Draper, Jonathan S, Bahrami, Ahmad R, Morton, Ian, Moore, Harry D, Andrews, Peter W

“…We have used RNA interference (RNAi) to downregulate beta 2-microglobulin and Oct4 in human embryonal carcinoma (hEC) cells and embryonic stem (hES) cells,…”
Get full text