Search Results - "Draper, Bruce"

The telomere bouquet is a hub where meiotic double-strand breaks, synapsis, and stable homolog juxtaposition are coordinated in the zebrafish, Danio rerio by Blokhina, Yana P, Nguyen, An D, Draper, Bruce W, Burgess, Sean M

“…Meiosis is a cellular program that generates haploid gametes for sexual reproduction. While chromosome events that contribute to reducing ploidy (homologous…”
Get full text

Genetic regulation of sex determination and maintenance in zebrafish (Danio rerio) by Kossack, Michelle E, Draper, Bruce W

“…Over the last several decades zebrafish (Danio rerio) has become a major model organism for the study of vertebrate development and physiology. Given this, it…”
Get full text

Identification of Germline Stem Cells in Zebrafish by Draper, Bruce W

“…Both male and female zebrafish have a population of germline stem cells that produce gametes throughout the life of the fish. These cells localize to specific…”
Get more information

Bmp15 Is an Oocyte-Produced Signal Required for Maintenance of the Adult Female Sexual Phenotype in Zebrafish by Dranow, Daniel B, Hu, Kevin, Bird, April M, Lawry, S Terese, Adams, Melissa T, Sanchez, Angelica, Amatruda, James F, Draper, Bruce W

“…Although the zebrafish is a major model organism, how they determine sex is not well understood. In domesticated zebrafish, sex determination appears to be…”
Get full text

Fibroblast growth factor signaling is required for early somatic gonad development in zebrafish by Leerberg, Dena M, Sano, Kaori, Draper, Bruce W

“…The vertebrate ovary and testis develop from a sexually indifferent gonad. During early development of the organism, primordial germ cells (the gamete lineage)…”
Get full text

Dmrt1 is necessary for male sexual development in zebrafish by Webster, Kaitlyn A., Schach, Ursula, Ordaz, Angel, Steinfeld, Jocelyn S., Draper, Bruce W., Siegfried, Kellee R.

“…The dmrt1 (doublesex and mab-3 related transcription factor 1) gene is a key regulator of sex determination and/or gonadal sex differentiation across metazoan…”
Get full text

Fibroblast Growth Factor Receptors Function Redundantly During Zebrafish Embryonic Development by Leerberg, Dena M, Hopton, Rachel E, Draper, Bruce W

“…Fibroblast growth factor (Fgf) signaling regulates many processes during development. In most cases, one tissue layer secretes an Fgf ligand that binds and…”
Get full text

Identification of Germ-Line Stem Cells in Zebrafish by Draper, Bruce W

“…Both male and female zebrafish have a population of germ-line stem cells that produce gametes throughout the life of the fish. These cells localize to specific…”
Get more information

nanos3 maintains germline stem cells and expression of the conserved germline stem cell gene nanos2 in the zebrafish ovary by Beer, Rebecca L., Draper, Bruce W.

“…Female zebrafish have a prolific reproductive capacity, suggesting that a germline stem cell (GSC) population drives oocyte production. However, a zebrafish…”
Get full text

Germ cells are required to maintain a stable sexual phenotype in adult zebrafish by Dranow, Daniel B., Tucker, Richard P., Draper, Bruce W.

“…Sex in zebrafish is not determined by a major chromosomal locus, but instead relies on a mechanism that is influenced by a germ cell-derived signal, as animals…”
Get full text

Visual object tracking using adaptive correlation filters by Bolme, David S, Beveridge, J Ross, Draper, Bruce A, Yui Man Lui

“…Although not commonly used, correlation filters can track complex objects through rotations, occlusions and other distractions at over 20 times the rate of…”
Get full text

Rad21l1 cohesin subunit is dispensable for spermatogenesis but not oogenesis in zebrafish by Blokhina, Yana P, Frees, Michelle A, Nguyen, An, Sharifi, Masuda, Chu, Daniel B, Bispo, Kristi, Olaya, Ivan, Draper, Bruce W, Burgess, Sean M

“…During meiosis I, ring-shaped cohesin complexes play important roles in aiding the proper segregation of homologous chromosomes. RAD21L is a meiosis-specific…”
Get full text

Rbpms2 promotes female fate upstream of the nutrient sensing Gator2 complex component Mios by Wilson, Miranda L., Romano, Shannon N., Khatri, Nitya, Aharon, Devora, Liu, Yulong, Kaufman, Odelya H., Draper, Bruce W., Marlow, Florence L.

“…Reproductive success relies on proper establishment and maintenance of biological sex. In many animals, including mammals, the primary gonad is initially ovary…”
Get full text

Female Sex Development and Reproductive Duct Formation Depend on Wnt4a in Zebrafish by Kossack, Michelle E, High, Samantha K, Hopton, Rachel E, Yan, Yi-Lin, Postlethwait, John H, Draper, Bruce W

“…In laboratory strains of zebrafish, sex determination occurs in the absence of a typical sex chromosome and it is not known what regulates the proportion of…”
Get full text

Motion Segmentation via Generalized Curvatures by Arn, Robert T., Narayana, Pradyumna, Emerson, Tegan, Draper, Bruce A., Kirby, Michael, Peterson, Chris

“…New depth sensors, like the Microsoft Kinect, produce streams of human pose data. These discrete pose streams can be viewed as noisy samples of an underlying…”
Get full text

Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary by Liu, Yulong, Kossack, Michelle E, McFaul, Matthew E, Christensen, Lana N, Siebert, Stefan, Wyatt, Sydney R, Kamei, Caramai N, Horst, Samuel, Arroyo, Nayeli, Drummond, Iain A, Juliano, Celina E, Draper, Bruce W

“…Zebrafish are an established research organism that has made many contributions to our understanding of vertebrate tissue and organ development, yet there are…”
Get full text

Macrophage activation drives ovarian failure and masculinization in zebrafish by Bravo, Paloma, Liu, Yulong, Draper, Bruce W, Marlow, Florence L

“…BMP15 is a conserved regulator of ovarian development and maintenance in vertebrates. In humans, premature ovarian insufficiency is caused by autoimmunity and…”
Get full text

Electric field-guided collective motility initiation of large epidermal cell groups by Sun, Yaohui, Reid, Brian, Zhang, Yan, Zhu, Kan, Ferreira, Fernando, Estrada, Alejandro, Sun, Yuxin, Draper, Bruce W, Yue, Haicen, Copos, Calina, Lin, Francis, Bernadskaya, YelenaY, Zhao, Min, Mogilner, Alex

“…Recent research has elucidated mechanochemical pathways of single cell polarization, but much less is known about collective motility initiation in adhesive…”
Get full text

A Role for Piwi and piRNAs in Germ Cell Maintenance and Transposon Silencing in Zebrafish by Houwing, Saskia, Kamminga, Leonie M., Berezikov, Eugene, Cronembold, Daniela, Girard, Angélique, van den Elst, Hans, Filippov, Dmitri V., Blaser, Heiko, Raz, Erez, Moens, Cecilia B., Plasterk, Ronald H.A., Hannon, Gregory J., Draper, Bruce W., Ketting, René F.

“…Piwi proteins specify an animal-specific subclass of the Argonaute family that, in vertebrates, is specifically expressed in germ cells. We demonstrate that…”
Get full text

Gonadal soma controls ovarian follicle proliferation through Gsdf in zebrafish by Yan, Yi‐Lin, Desvignes, Thomas, Bremiller, Ruth, Wilson, Catherine, Dillon, Danielle, High, Samantha, Draper, Bruce, Buck, Charles Loren, Postlethwait, John

“…Background: Aberrant signaling between germ cells and somatic cells can lead to reproductive disease and depends on diffusible signals, including transforming…”
Get full text