Search Results - "Draper, A"

The Advantages and Challenges of Using Endolysins in a Clinical Setting by Murray, Ellen, Draper, Lorraine A, Ross, R Paul, Hill, Colin

“…Antibiotic-resistant pathogens are increasingly more prevalent and problematic. Traditional antibiotics are no longer a viable option for dealing with these…”
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ΦCrAss001 represents the most abundant bacteriophage family in the human gut and infects Bacteroides intestinalis by Shkoporov, Andrey N., Khokhlova, Ekaterina V., Fitzgerald, C. Brian, Stockdale, Stephen R., Draper, Lorraine A., Ross, R. Paul, Hill, Colin

“…CrAssphages are an extensive and ubiquitous family of tailed bacteriophages, predicted to infect bacteria of the order Bacteroidales . Despite being found in…”
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The Human Gut Virome Is Highly Diverse, Stable, and Individual Specific by Shkoporov, Andrey N., Clooney, Adam G., Sutton, Thomas D.S., Ryan, Feargal J., Daly, Karen M., Nolan, James A., McDonnell, Siobhan A., Khokhlova, Ekaterina V., Draper, Lorraine A., Forde, Amanda, Guerin, Emma, Velayudhan, Vimalkumar, Ross, R. Paul, Hill, Colin

“…The human gut contains a vast array of viruses, mostly bacteriophages. The majority remain uncharacterized, and their roles in shaping the gut microbiome and…”
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Whole-Virome Analysis Sheds Light on Viral Dark Matter in Inflammatory Bowel Disease by Clooney, Adam G., Sutton, Thomas D.S., Shkoporov, Andrey N., Holohan, Ross K., Daly, Karen M., O’Regan, Orla, Ryan, Feargal J., Draper, Lorraine A., Plevy, Scott E., Ross, R. Paul, Hill, Colin

“…The human gut virome is thought to significantly impact the microbiome and human health. However, most virome analyses have been performed on a limited…”
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Biology and Taxonomy of crAss-like Bacteriophages, the Most Abundant Virus in the Human Gut by Guerin, Emma, Shkoporov, Andrey, Stockdale, Stephen R., Clooney, Adam G., Ryan, Feargal J., Sutton, Thomas D.S., Draper, Lorraine A., Gonzalez-Tortuero, Enrique, Ross, R. Paul, Hill, Colin

“…CrAssphages represent the most abundant virus in the human gut microbiota, but the lack of available genome sequences for comparison has kept them enigmatic…”
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Diagnosis and Management of Childhood Obstructive Sleep Apnea Syndrome by MARCUS, Carole L, BROOKS, Lee Jay, LEHMANN, Christopher, SHIFFMAN, Richard N, DRAPER, Kari A, GOZAL, David, HALBOWER, Ann Carol, JONES, Jacqueline, SCHECHTER, Michael S, SHELDON, Stephen Howard, SPRUYT, Karen, WARD, Davidson

“…This revised clinical practice guideline, intended for use by primary care clinicians, provides recommendations for the diagnosis and management of the…”
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Optogenetic silencing of a corticotropin-releasing factor pathway from the central amygdala to the bed nucleus of the stria terminalis disrupts sustained fear by Asok, A, Draper, A, Hoffman, A F, Schulkin, J, Lupica, C R, Rosen, J B

“…The lateral central nucleus of the amygdala (CeA L ) and the dorsolateral bed nucleus of the stria terminalis (BNST DL ) coordinate the expression of shorter-…”
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Diagnosis and management of childhood obstructive sleep apnea syndrome by Marcus, Carole L, Brooks, Lee Jay, Draper, Kari A, Gozal, David, Halbower, Ann Carol, Jones, Jacqueline, Schechter, Michael S, Ward, Sally Davidson, Sheldon, Stephen Howard, Shiffman, Richard N, Lehmann, Christopher, Spruyt, Karen

“…This technical report describes the procedures involved in developing recommendations on the management of childhood obstructive sleep apnea syndrome (OSAS)…”
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A TALE OF TWO POPULATIONS: THE CONTRIBUTION OF MERGER AND SECULAR PROCESSES TO THE EVOLUTION OF ACTIVE GALACTIC NUCLEI by DRAPER, A. R, BALLANTYNE, D. R

“…Due to the co-evolution of supermassive black holes and their host galaxies, understanding the mechanisms that trigger active galactic nuclei (AGNs) is…”
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Eosinophilic pneumonia and COVID-19 vaccination by May, J, Draper, A, Aul, R

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Long-term colonisation with donor bacteriophages following successful faecal microbial transplantation by Draper, L A, Ryan, F J, Smith, M K, Jalanka, J, Mattila, E, Arkkila, P A, Ross, R P, Satokari, R, Hill, C

“…Faecal microbiota transplantation (FMT) is used in the treatment of recurrent Clostridium difficile infection. Its success is typically attributed to the…”
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Visual object tracking using adaptive correlation filters by Bolme, David S, Beveridge, J Ross, Draper, Bruce A, Yui Man Lui

“…Although not commonly used, correlation filters can track complex objects through rotations, occlusions and other distractions at over 20 times the rate of…”
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Autochthonous faecal viral transfer (FVT) impacts the murine microbiome after antibiotic perturbation by Draper, Lorraine A, Ryan, Feargal J, Dalmasso, Marion, Casey, Pat G, McCann, Angela, Velayudhan, Vimalkumar, Ross, R Paul, Hill, Colin

“…It has become increasingly accepted that establishing and maintaining a complex and diverse gut microbiota is fundamental to human health. There are growing…”
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Characterization of an Endolysin Targeting Clostridioides difficile That Affects Spore Outgrowth by Mondal, Shakhinur Islam, Akter, Arzuba, Draper, Lorraine A., Ross, R. Paul, Hill, Colin

“…Clostridioides difficile is a spore-forming enteric pathogen causing life-threatening diarrhoea and colitis. Microbial disruption caused by antibiotics has…”
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Expansion of known ssRNA phage genomes: From tens to over a thousand by Callanan, J, Stockdale, S R, Shkoporov, A, Draper, L A, Ross, R P, Hill, C

“…The first sequenced genome was that of the 3569-nucleotide single-stranded RNA (ssRNA) bacteriophage MS2. Despite the recent accumulation of vast amounts of…”
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Pleural effusions: Infectious, inflammatory or ‘other’? by Johns, I., Draper, A.

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Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction by Williams, Ashley S., Koves, Timothy R., Davidson, Michael T., Crown, Scott B., Fisher-Wellman, Kelsey H., Torres, Maria J., Draper, James A., Narowski, Tara M., Slentz, Dorothy H., Lantier, Louise, Wasserman, David H., Grimsrud, Paul A., Muoio, Deborah M.

“…This study sought to examine the functional significance of mitochondrial protein acetylation using a double knockout (DKO) mouse model harboring…”
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Reproducible protocols for metagenomic analysis of human faecal phageomes by Shkoporov, Andrey N, Ryan, Feargal J, Draper, Lorraine A, Forde, Amanda, Stockdale, Stephen R, Daly, Karen M, McDonnell, Siobhan A, Nolan, James A, Sutton, Thomas D S, Dalmasso, Marion, McCann, Angela, Ross, R Paul, Hill, Colin

“…Recent studies have demonstrated that the human gut is populated by complex, highly individual and stable communities of viruses, the majority of which are…”
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Stability of the human gut virome and effect of gluten-free diet by Garmaeva, Sanzhima, Gulyaeva, Anastasia, Sinha, Trishla, Shkoporov, Andrey N., Clooney, Adam G., Stockdale, Stephen R., Spreckels, Johanne E., Sutton, Thomas D.S., Draper, Lorraine A., Dutilh, Bas E., Wijmenga, Cisca, Kurilshikov, Alexander, Fu, Jingyuan, Hill, Colin, Zhernakova, Alexandra

“…The human gut microbiome consists of bacteria, archaea, eukaryotes, and viruses. The gut viruses are relatively underexplored. Here, we longitudinally analyzed…”
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Cholesterol synthesis enzyme SC4MOL is fine-tuned by sterols and targeted for degradation by the E3 ligase MARCHF6 by Qian, Lydia, Scott, Nicola A., Capell-Hattam, Isabelle M., Draper, Eliza A., Fenton, Nicole M., Luu, Winnie, Sharpe, Laura J., Brown, Andrew J.

“…Cholesterol biosynthesis is a highly regulated pathway, with over 20 enzymes controlled at the transcriptional and posttranslational levels. While some enzymes…”
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