Search Results - "Dransfield, M T"
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Computed tomographic measures of airway morphology in smokers and never-smoking normals
Published in Journal of applied physiology (1985) (15-03-2014)“…Bronchial wall area percent (WA% = 100 × wall area/total bronchial cross sectional area) is a standard computed tomographic (CT) measure of central airway…”
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Use of beta blockers and the risk of death in hospitalised patients with acute exacerbations of COPD
Published in Thorax (01-04-2008)“…Cardiovascular disease is a major cause of death in patients with chronic obstructive pulmonary disease (COPD) and predicts hospitalisation for acute…”
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Mepolizumab in the treatment of eosinophilic chronic obstructive pulmonary disease
Published in International journal of chronic obstructive pulmonary disease (01-08-2019)“…Despite maximal medical therapy, a subset of patients with chronic obstructive pulmonary disease continue to suffer acute exacerbations. It is also clear that…”
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The Association Between Neighborhood Socioeconomic Disadvantage and Chronic Obstructive Pulmonary Disease
Published in International journal of chronic obstructive pulmonary disease (01-01-2020)“…Individual socioeconomic status has been shown to influence the outcomes of patients with chronic obstructive pulmonary disease (COPD). However, contextual…”
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Life-Space mobility and clinical outcomes in COPD
Published in International journal of chronic obstructive pulmonary disease (01-01-2018)“…Social isolation is a common experience in patients with COPD but is not captured by existing patient-reported outcomes, and its association with clinical…”
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Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis
Published in International journal of chronic obstructive pulmonary disease (01-12-2019)“…Bronchodilator responsiveness (BDR) is prevalent in COPD, but its clinical implications remain unclear. We explored the significance of BDR, defined by…”
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Determinants of successful completion of pulmonary rehabilitation in COPD
Published in International journal of chronic obstructive pulmonary disease (01-01-2016)“…Despite known benefits, a significant proportion of patients with COPD do not complete pulmonary rehabilitation (PR). Little is known regarding which factors…”
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A randomized trial of once-daily fluticasone furoate/vilanterol or vilanterol versus placebo to determine effects on arterial stiffness in COPD
Published in International journal of chronic obstructive pulmonary disease (01-01-2017)“…Chronic obstructive pulmonary disease (COPD) is associated with increased cardiovascular morbidity and mortality. Elevated arterial stiffness, measured by…”
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The use of a standardized order set reduces systemic corticosteroid dose and length of stay for individuals hospitalized with acute exacerbations of COPD: a cohort study
Published in International journal of chronic obstructive pulmonary disease (01-01-2018)“…Systemic corticosteroids (SC) are an integral part of managing acute exacerbations of COPD (AECOPD). However, the optimal dose and duration vary widely in…”
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Velocity Transfer Function In The Right Pulmonary Artery And Impaired Cardiopulmonary Reserve In COPD
Published in International journal of chronic obstructive pulmonary disease (01-12-2019)“…Oleg F Sharifov,1 Thomas S Denney Jr,2 J Michael Wells,1,3,4 Gregory A Payne,1,4 Swati Gulati,1,3 Himanshu Gupta,5 Mark T Dransfield,1,3,4 Steven G Lloyd1,4…”
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Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis [Corrigendum]
Published in International journal of chronic obstructive pulmonary disease (31-05-2020)“…Funding This study was supported by R01HL125432-01A1 (MBD), T32HL007106-41 (RMB), and TL1TR001883-01 (RGB). SPIROMICS was supported by contracts from the…”
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Novel Respiratory Disability Score Predicts COPD Exacerbations and Mortality in the SPIROMICS Cohort
Published in International journal of chronic obstructive pulmonary disease (01-01-2020)“…Some COPD patients develop extreme breathlessness, decreased exercise capacity and poor health status yet respiratory disability is poorly characterized as a…”
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Pulmonary artery to aorta ratio is associated with cardiac structure and functional changes in mild-to-moderate COPD
Published in International journal of chronic obstructive pulmonary disease (01-01-2017)“…The ratio of the diameter of the pulmonary artery (PA) to the diameter of the aorta (PA:A) on computed tomography (CT) imaging is associated with both COPD…”
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Simvastatin for the Prevention of Exacerbations in Moderate-to-Severe COPD
Published in The New England journal of medicine (05-06-2014)“…In this study involving patients who were at high risk for exacerbations of chronic obstructive pulmonary disease but had no other indication for statin…”
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COPD and multimorbidity: recognising and addressing a syndemic occurrence
Published in The lancet respiratory medicine (01-11-2023)“…Most patients with chronic obstructive pulmonary disease (COPD) have at least one additional, clinically relevant chronic disease. Those with the most severe…”
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Efficacy and Safety of the CFTR Potentiator Icenticaftor (QBW251) in COPD: Results from a Phase 2 Randomized Trial
Published in International journal of chronic obstructive pulmonary disease (01-01-2020)“…Excess mucus plays a key role in COPD pathogenesis. Cigarette smoke-induced cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction may…”
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