Search Results - "Drake, T. M."

The use of biochemical markers of bone remodeling in multiple myeloma: a report of the International Myeloma Working Group by Terpos, E, Dimopoulos, M A, Sezer, O, Roodman, D, Abildgaard, N, Vescio, R, Tosi, P, Garcia-Sanz, R, Davies, F, Chanan-Khan, A, Palumbo, A, Sonneveld, P, Drake, M T, Harousseau, J-L, Anderson, K C, Durie, B G M

“…Lytic bone disease is a frequent complication of multiple myeloma (MM). Lytic lesions rarely heal and X-rays are of limited value in monitoring bone…”
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A loss of host-derived MMP-7 promotes myeloma growth and osteolytic bone disease in vivo by Lwin, S T, Fowler, J A, Drake, M T, Edwards, J R, Lynch, C C, Edwards, C M

“…Matrix metalloproteinases (MMPs) play a critical role in cancer pathogenesis, including tumor growth and osteolysis within the bone marrow microenvironment…”
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Isolation and characterization of human osteoblasts from needle biopsies without in vitro culture by Fujita, K., Roforth, M. M., Atkinson, E. J., Peterson, J. M., Drake, M. T., McCready, L. K., Farr, J. N., Monroe, D. G., Khosla, S.

“…Summary We isolate and characterize osteoblasts from humans without in vitro culture. These techniques should be broadly applicable to studying the…”
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Phase I trial of rituximab, cladribine, and temsirolimus (RCT) for initial therapy of mantle cell lymphoma by Inwards, D.J., Fishkin, P.A., LaPlant, B.R., Drake, M.T., Kurtin, P.J., Nikcevich, D.A., Wender, D.B., Lair, B.S., Witzig, T.E.

“…We conducted this trial to determine the maximum tolerated dose (MTD) of temsirolimus added to an established regimen comprised of rituximab and cladribine for…”
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Pharmacological management to prevent ileus in major abdominal surgery: a systematic review and meta-analysis by Drake, T. M., Ward, A. E.

“…Background Prolonged ileus is a common complication following gastrointestinal surgery, with an incidence of up to 40 %. Investigations examining…”
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Hypovitaminosis D in psychogeriatric inpatients by Lapid, Maria I, Drake, M. T, Geske, J. R, Mundis, C. B, Hegard, T. L, Kung, S, Frye, M. A

“…OBJECTIVES: This study investigated the rate of hypovitaminosis D in psychogeriatric inpatients and explored whether any associations exist between vitamin D…”
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A systematic review of the incidence of and risk factors for postoperative atrial fibrillation following general surgery by Chebbout, R., Heywood, E. G., Drake, T. M., Wild, J. R. L., Lee, J., Wilson, M., Lee, M. J.

“…Summary Atrial fibrillation is a common cardiac arrhythmia and can occur de novo following a surgical procedure. It is associated with increased inpatient and…”
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Systematic review of the use of big data to improve surgery in low‐ and middle‐income countries by Knight, S. R., Ots, R., Maimbo, M., Drake, T. M., Fairfield, C. J., Harrison, E. M.

“…Background Technological advances have led to the generation of large amounts of data, both in surgical research and practice. Despite this, it is unclear how…”
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Association of prior treatment with nitrogen-containing bisphosphonates on outcomes of COVID-19 positive patients by Lee, R.H., Curtis, J., Drake, M.T., Bobo Tanner, S., Lenert, L., Schmader, K., Pieper, C., North, R., Lyles, K.W.

“…Summary COVID-19 infection has resulted in significant morbidity and mortality globally, especially among older adults. Repurposed drugs have demonstrated…”
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Longitudinal analysis of reporting and quality of systematic reviews in high‐impact surgical journals by Chapman, S. J., Drake, T. M., Bolton, W. S., Barnard, J., Bhangu, A.

“…Background The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) Statement aims to optimize the reporting of systematic reviews. The…”
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Incidence and predictors of osteoporotic fractures in patients with Barrett's oesophagus: a population‐based nested case‐control study by Kumar, S., Drake, M. T., Schleck, C. D., Johnson, M. L., Alexander, J. A., Katzka, D. A., Iyer, P. G.

“…Summary Background Proton pump inhibitors (PPI) are inconsistently associated with osteoporotic fractures. Barrett's oesophagus (BO) patients are treated with…”
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Trends in subtrochanteric, diaphyseal, and distal femur fractures, 1984–2007 by Ng, A. C., Drake, M. T., Clarke, B. L., Sems, S. A., Atkinson, E. J., Achenbach, S. J., Melton, L. J.

“…Summary The incidence of non-hip femur fractures increased between 1984 and 2007, with an increase in the rates for women after 1996. Introduction Recent…”
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Positron emission tomography-computed tomography in the diagnostic evaluation of smoldering multiple myeloma: identification of patients needing therapy by Siontis, B, Kumar, S, Dispenzieri, A, Drake, M T, Lacy, M Q, Buadi, F, Dingli, D, Kapoor, P, Gonsalves, W, Gertz, M A, Rajkumar, S V

“…We studied 188 patients with a suspected smoldering multiple myeloma (MM) who had undergone a positron emission tomography-computed tomography (PET-CT) scan as…”
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Bisphosphonate therapeutics in bone disease: the hard and soft data on osteoclast inhibition by Drake, Matthew T, Cremers, Serge C L M

“…Bisphosphonates are chemically stable structural analogs of inorganic pyrophosphate. Owing to their ability to inhibit osteoclast activity, bisphosphonates…”
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Peri‐operative acute kidney injury – a reply by Drake, T. M., Ahmed, W., Khaw, R. A., Yasin, I., Baker, D., Mills, E., Kamarajah, S. K., Borakati, A.

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Phase I trial of rituximab, cladribine, and temsirolimus (RCT) for initial therapy of mantle cell lymphoma by Inwards, D.J., Fishkin, P.A., LaPlant, B.R., Drake, M.T., Kurtin, P.J., Nikcevich, D.A., Wender, D.B., Lair, B.S., Witzig, T.E.

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A Randomised Assessment of Trainee Doctors’ Understanding and Interpretation of Diagnostic Test Results by Parker, V. L., Ritchie, J. E., Drake, T. M., Hookham, J., Balasubramanian, S. P.

“…Introduction Doctors are unfamiliar with diagnostic accuracy parameters despite routine clinical use of diagnostic tests to estimate disease probability…”
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The assembly of AP-3 adaptor complex-containing clathrin-coated vesicles on synthetic liposomes by Drake, M T, Zhu, Y, Kornfeld, S

“…The heterotetrameric adaptor protein complex AP-3 has been shown to function in the sorting of proteins to the endosomal/lysosomal system. However, the…”
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Resource variation in colorectal surgery: a national centre level analysis by Drake, T. M., Lee, M. J., Senapati, A., Brown, S. R.

“…Aim Delivery of quality colorectal surgery requires adequate resources. We set out to assess the relationship between resources and outcomes in English…”
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Vitamin D insufficiency is associated with an increased risk of early clinical failure in follicular lymphoma by Tracy, S I, Maurer, M J, Witzig, T E, Drake, M T, Ansell, S M, Nowakowski, G S, Thompson, C A, Inwards, D J, Johnston, P B, Micallef, I N, Allmer, C, Macon, W R, Weiner, G J, Slager, S L, Habermann, T M, Link, B K, Cerhan, J R

“…We evaluated whether vitamin D insufficiency (VDI; 25(OH)D <20 ng/ml) was associated with adverse outcomes among follicular lymphoma (FL) patients using an…”
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