Search Results - "Drake, Amanda"

Maternal influences on fetal brain development: The role of nutrition, infection and stress, and the potential for intergenerational consequences by Fitzgerald, Eamon, Hor, Kahyee, Drake, Amanda J.

“…An optimal early life environment is crucial for ensuring ideal neurodevelopmental outcomes. Brain development consists of a finely tuned series of spatially…”
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Influence of sleep deprivation and circadian misalignment on cortisol, inflammatory markers, and cytokine balance by Wright, Kenneth P, Drake, Amanda L, Frey, Danielle J, Fleshner, Monika, Desouza, Christopher A, Gronfier, Claude, Czeisler, Charles A

“…Highlights • Sleep deprivation and circadian misalignment have opposite effects on cortisol. • Acute total sleep deprivation increases cortisol levels. •…”
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Impact of maternal obesity on offspring obesity and cardiometabolic disease risk by Drake, Amanda J, Reynolds, Rebecca M

“…The prevalence of obesity among pregnant women is increasing. In addition to the short-term complications of obesity during pregnancy in both mother and child,…”
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Non-genetic inheritance via the male germline in mammals by Baxter, Faye A, Drake, Amanda J

“…Numerous studies in humans and in animal models have demonstrated that exposure to adverse environmental conditions in early life results in long-term…”
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Examining learners' engagement patterns and knowledge outcome in an experiential learning intervention for youth's social media literacy by Zou, Wenting, Purington Drake, Amanda, Masur, Philipp K., Whitlock, Janis, Bazarova, Natalie N.

“…Social media has become an integral part of youth's daily lives. Though it brings many benefits such as creative self-expression and opportunities for social…”
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Glucocorticoids as mediators of developmental programming effects by Khulan, Batbayar, PhD, Drake, Amanda J., MBBS, PhD

“…Epidemiological evidence suggests that exposure to an adverse environment in early life is associated with an increased risk of cardio-metabolic and behavioral…”
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Characteristics of salivary telomere length shortening in preterm infants by Schneper, Lisa M, Drake, Amanda J, Dunstan, Taylor, Kotenko, Iulia, Notterman, Daniel A, Piyasena, Chinthika

“…To examine the association between gestational age, telomere length (TL) and rate of shortening in newborns. Genomic DNA was isolated from buccal samples of 39…”
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Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk by Zannas, Anthony S., Jia, Meiwen, Hafner, Kathrin, Baumert, Jens, Wiechmann, Tobias, Pape, Julius C., Arloth, Janine, Ködel, Maik, Martinelli, Silvia, Roitman, Maria, Röh, Simone, Haehle, Andreas, Emeny, Rebecca T., Iurato, Stella, Carrillo-Roa, Tania, Lahti, Jari, Räikkönen, Katri, Eriksson, Johan G., Drake, Amanda J., Waldenberger, Melanie, Wahl, Simone, Kunze, Sonja, Lucae, Susanne, Bradley, Bekh, Gieger, Christian, Hausch, Felix, Smith, Alicia K., Ressler, Kerry J., Müller-Myhsok, Bertram, Ladwig, Karl-Heinz, Rein, Theo, Gassen, Nils C., Binder, Elisabeth B.

“…Aging and psychosocial stress are associated with increased inflammation and disease risk, but the underlying molecular mechanisms are unclear. Because both…”
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Preterm birth in evolutionary context: a predictive adaptive response? by Williams, Thomas C, Drake, Amanda J

“…Preterm birth is a significant public health problem worldwide, leading to substantial mortality in the newborn period, and a considerable burden of…”
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Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial by Chiswick, Carolyn, MBChB, Reynolds, Rebecca M, Prof, Denison, Fiona, MD, Drake, Amanda J, PhD, Forbes, Shareen, PhD, Newby, David E, Prof, Walker, Brian R, Prof, Quenby, Siobhan, Prof, Wray, Susan, Prof, Weeks, Andrew, Prof, Lashen, Hany, MD, Rodriguez, Aryelly, MSc, Murray, Gordon, Prof, Whyte, Sonia, MSc, Norman, Jane E, Prof

“…Summary Background Maternal obesity is associated with increased birthweight, and obesity and premature mortality in adult offspring. The mechanism by which…”
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DNA methylation and brain structure and function across the life course: A systematic review by Wheater, Emily N.W., Stoye, David Q., Cox, Simon R., Wardlaw, Joanna M., Drake, Amanda J., Bastin, Mark E., Boardman, James P.

“…•60 studies of association between DNAm and human brain MRI were identified.•Differential DNAm is associated with brain structure and function throughout…”
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Prematurity and programming of cardiovascular disease risk: a future challenge for public health? by Bayman, Elizabeth, Drake, Amanda J, Piyasena, Chinthika

“…There is substantial epidemiological evidence linking low birth weight with adult cardiometabolic disease risk factors. This has led to the concept of 'early…”
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Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides by Weir, Graeme, Ramage, Lynne E., Akyol, Murat, Rhodes, Jonathan K., Kyle, Catriona J., Fletcher, Alison M., Craven, Thomas H., Wakelin, Sonia J., Drake, Amanda J., Gregoriades, Maria-Lena, Ashton, Ceri, Weir, Nick, van Beek, Edwin J.R., Karpe, Fredrik, Walker, Brian R., Stimson, Roland H.

“…Current understanding of in vivo human brown adipose tissue (BAT) physiology is limited by a reliance on positron emission tomography (PET)/computed tomography…”
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Intergenerational transmission of programmed effects: public health consequences by Drake, Amanda J, Liu, Lincoln

“…Epidemiological studies have shown that the environment experienced in early life can ‘programme’ susceptibility to later disease. Furthermore, there is…”
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Adrenal suppression with glucocorticoid therapy: still a problem after all these years? by Bayman, Elizabeth, Drake, Amanda J

“…Patients with adrenal suppression may remain well if their normal GC requirements are provided by the GC treatment itself; however, in some cases, this is…”
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Metabolic adaptations to hypoxia in the neonatal mouse forebrain can occur independently of the transporters SLC7A5 and SLC3A2 by Fitzgerald, Eamon, Roberts, Jennie, Tennant, Daniel A., Boardman, James P., Drake, Amanda J.

“…Neonatal encephalopathy due to hypoxia–ischemia is associated with adverse neurodevelopmental effects. The involvement of branched chain amino acids (BCAAs) in…”
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Mechanisms underlying the role of glucocorticoids in the early life programming of adult disease by Drake, Amanda J, Tang, Justin I, Nyirenda, Moffat J

“…Compelling epidemiological evidence suggests that exposure to an adverse intrauterine environment, manifested by low-birth weight, is associated with…”
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Proposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodents by van den Driesche, Sander, Walker, Marion, McKinnell, Chris, Scott, Hayley M, Eddie, Sharon L, Mitchell, Rod T, Seckl, Jonathan R, Drake, Amanda J, Smith, Lee B, Anderson, Richard A, Sharpe, Richard M

“…Reproductive disorders that are common/increasing in prevalence in human males may arise because of deficient androgen production/action during a fetal…”
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Inter-relationship between testicular dysgenesis and Leydig cell function in the masculinization programming window in the rat by van den Driesche, Sander, Kolovos, Petros, Platts, Sophie, Drake, Amanda J, Sharpe, Richard M

“…The testicular dysgenesis syndrome (TDS) hypothesis proposes that maldevelopment of the testis, irrespective of cause, leads to malfunction of the somatic…”
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Preterm Birth and the Risk of Neurodevelopmental Disorders - Is There a Role for Epigenetic Dysregulation? by Fitzgerald, Eamon, Boardman, James P, Drake, Amanda J

“…Preterm Birth (PTB) accounts for approximately 11% of all births worldwide each year and is a profound physiological stressor in early life. The burden of…”
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