Search Results - "Draheim, Roger R"

Silver Nanowires: Synthesis, Antibacterial Activity and Biomedical Applications by Jones, Richard, Draheim, Roger, Roldo, Marta

“…[...]the authors show that FESEM images of treated E. coli cells exhibit high levels of cell membrane disruption and overall lysis, which would be consistent…”
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Evaluation of Antibacterial and Cytotoxicity Properties of Silver Nanowires and Their Composites with Carbon Nanotubes for Biomedical Applications by De Mori, Arianna, Jones, Richard S, Cretella, Matteo, Cerri, Guido, Draheim, Roger R, Barbu, Eugen, Tozzi, Gianluca, Roldo, Marta

“…In this work, we prepared silver nanowires (AgNWs) via the polyol method in the presence or absence of single wall carbon nanotubes (CNTs) and tested their…”
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Sustained Release from Injectable Composite Gels Loaded with Silver Nanowires Designed to Combat Bacterial Resistance in Bone Regeneration Applications by De Mori, Arianna, Hafidh, Meena, Mele, Natalia, Yusuf, Rahmi, Cerri, Guido, Gavini, Elisabetta, Tozzi, Gianluca, Barbu, Eugen, Conconi, Mariateresa, Draheim, Roger R, Roldo, Marta

“…One-dimensional nanostructures, such as silver nanowires (AgNWs), have attracted considerable attention owing to their outstanding electrical, thermal and…”
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Antibacterial PMMA Composite Cements with Tunable Thermal and Mechanical Properties by De Mori, Arianna, Di Gregorio, Emanuela, Kao, Alexander Peter, Tozzi, Gianluca, Barbu, Eugen, Sanghani-Kerai, Anita, Draheim, Roger R, Roldo, Marta

“…PMMA-based cements are the most used bone cements in vertebroplasty and total hip arthroplasty. However, they present several drawbacks, including…”
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A Modular High-Throughput In Vivo Screening Platform Based on Chimeric Bacterial Receptors by Lehning, Christina E, Heidelberger, Jan B, Reinhard, John, Nørholm, Morten H. H, Draheim, Roger R

“…Multidrug resistance (MDR) is a globally relevant problem that requires novel approaches. Two-component systems are a promising, yet untapped target for novel…”
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Structural characterization of AS1–membrane interactions from a subset of HAMP domains by Unnerståle, Sofia, Mäler, Lena, Draheim, Roger R.

“…HAMP domains convert an extracellular sensory input into an intracellular signaling response in a wide variety of membrane-embedded bacterial proteins. These…”
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Mutational Analysis of the Transmembrane Helix 2-HAMP Domain Connection in the Escherichia coli Aspartate Chemoreceptor Tar by WRIGHT, Gus A, CROWDER, Rachel L, DRAHEIM, Roger R, MANSON, Michael D

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Comparative Phenotypic, Proteomic, and Phosphoproteomic Analysis Reveals Different Roles of Serine/Threonine Phosphatase and Kinase in the Growth, Cell Division, and Pathogenicity of Streptococcus suis by Hu, Qiao, Yao, Lun, Liao, Xia, Zhang, Liang-Sheng, Li, Hao-Tian, Li, Ting-Ting, Jiang, Qing-Gen, Tan, Mei-Fang, Li, Lu, Draheim, Roger R, Huang, Qi, Zhou, Rui

“…Eukaryote-like serine/threonine kinases (STKs) and cognate phosphatases (STPs) comprise an important regulatory system in many bacterial pathogens. The…”
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CheZ Phosphatase Localizes to Chemoreceptor Patches via CheA-Short by Cantwell, Brian J, Draheim, Roger R, Weart, Richard B, Nguyen, Cameran, Stewart, Richard C, Manson, Michael D

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Antimicrobial compounds from an FDA‐approved drug library with activity against Streptococcus suis by Li, Haotian, Li, Tingting, Zhang, Liangsheng, Hu, Qiao, Liao, Xia, Jiang, Qinggen, Qiu, Xiuxiu, Li, Lu, Draheim, Roger R., Huang, Qi, Zhou, Rui

“…Aim Antimicrobial resistance (AMR) has become a global concern. Developing novel antimicrobials is one of the most effective approaches in tackling AMR…”
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Identification of transmembrane helix 1 (TM1) surfaces important for EnvZ dimerisation and signal output by Heininger, Annika, Yusuf, Rahmi, Lawrence, Robert J., Draheim, Roger R.

“…The Escherichia coli sensor kinase EnvZ modulates porin expression in response to various stimuli, including extracellular osmolarity, the presence of procaine…”
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Tuning Chemoreceptor Signaling by Positioning Aromatic Residues at the Lipid-Aqueous Interface by Yusuf, Rahmi, Lawrence, Robert J, Eke, Lucy V, Draheim, Roger R

“…Aromatic tuning facilitates stimulus-independent modulation of receptor output. The methodology is based upon the affinity of amphipathic aromatic residues,…”
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Differential repositioning of the second transmembrane helices from E. coli Tar and EnvZ upon moving the flanking aromatic residues by Botelho, Salomé C., Enquist, Karl, von Heijne, Gunnar, Draheim, Roger R.

“…Aromatic tuning, i.e. repositioning aromatic residues found at the cytoplasmic end of transmembrane (TM) domains within bacterial receptors, has been…”
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The Residue Composition of the Aromatic Anchor of the Second Transmembrane Helix Determines the Signaling Properties of the Aspartate/Maltose Chemoreceptor Tar of Escherichia coli by Adase, Christopher A, Draheim, Roger R, Manson, Michael D

“…Repositioning of the tandem aromatic residues (Trp-209 and Tyr-210) at the cytoplasmic end of the second transmembrane helix (TM2) modulates the signal output…”
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Employing aromatic tuning to modulate output from two-component signaling circuits by Yusuf, Rahmi, Draheim, Roger R

“…Two-component signaling circuits (TCSs) govern the majority of environmental, pathogenic and industrial processes undertaken by bacteria. Therefore,…”
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Residues at the cytoplasmic end of transmembrane helix 2 determine the signal output of the TarEc chemoreceptor by Adase, Christopher A, Draheim, Roger R, Rueda, Garrett, Desai, Raj, Manson, Michael D

“…Baseline signal output and communication between the periplasmic and cytoplasmic domains of the Escherichia coli aspartate chemoreceptor Tar(Ec) are both…”
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Residues at the Cytoplasmic End of Transmembrane Helix 2 Determine the Signal Output of the Tar Ec Chemoreceptor by Adase, Christopher A, Draheim, Roger R, Rueda, Garrett, Desai, Raj, Manson, Michael D

“…Baseline signal output and communication between the periplasmic and cytoplasmic domains of the Escherichia coli aspartate chemoreceptor Tar Ec are both…”
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Production of human tetraspanin proteins in Escherichia coli by Tarry, Michael, Skaar, Karin, Heijne, Gunnar von, Draheim, Roger R., Högbom, Martin

“…► Seventeen integral membrane human tetraspanins were screened for expression in Escherichia coli. ► Detergents for solubilization were screened using…”
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Forcing the Issue: Aromatic Tuning Facilitates Stimulus-Independent Modulation of a Two-Component Signaling Circuit by Nørholm, Morten H. H, von Heijne, Gunnar, Draheim, Roger R

“…Two-component signaling circuits allow bacteria to detect and respond to external stimuli. Unfortunately, the input stimulus remains unidentified for the…”
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Tuning a Bacterial Chemoreceptor with Protein−Membrane Interactions by Draheim, Roger R., Bormans, Arjan F., Lai, Run-Zhi, Manson, Michael D.

“…Chemoreceptors in Escherichia coli are homodimeric transmembrane proteins that convert environmental stimuli into intracellular signals controlling flagellar…”
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