Search Results - "Draheim, Roger"
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Silver Nanowires: Synthesis, Antibacterial Activity and Biomedical Applications
Published in Applied sciences (01-05-2018)“…[...]the authors show that FESEM images of treated E. coli cells exhibit high levels of cell membrane disruption and overall lysis, which would be consistent…”
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Antimicrobial compounds from an FDA‐approved drug library with activity against Streptococcus suis
Published in Journal of applied microbiology (01-03-2022)“…Aim Antimicrobial resistance (AMR) has become a global concern. Developing novel antimicrobials is one of the most effective approaches in tackling AMR…”
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Sustained Release from Injectable Composite Gels Loaded with Silver Nanowires Designed to Combat Bacterial Resistance in Bone Regeneration Applications
Published in Pharmaceutics (12-03-2019)“…One-dimensional nanostructures, such as silver nanowires (AgNWs), have attracted considerable attention owing to their outstanding electrical, thermal and…”
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Tuning Escherichia coli for membrane protein overexpression
Published in Proceedings of the National Academy of Sciences - PNAS (23-09-2008)“…A simple generic method for optimizing membrane protein overexpression in Escherichia coli is still lacking. We have studied the physiological response of the…”
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Antibacterial PMMA Composite Cements with Tunable Thermal and Mechanical Properties
Published in ACS omega (26-11-2019)“…PMMA-based cements are the most used bone cements in vertebroplasty and total hip arthroplasty. However, they present several drawbacks, including…”
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Evaluation of Antibacterial and Cytotoxicity Properties of Silver Nanowires and Their Composites with Carbon Nanotubes for Biomedical Applications
Published in International journal of molecular sciences (26-03-2020)“…In this work, we prepared silver nanowires (AgNWs) via the polyol method in the presence or absence of single wall carbon nanotubes (CNTs) and tested their…”
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Harnessing the Antibacterial Properties of Fluoridated Chitosan Polymers against Oral Biofilms
Published in Pharmaceutics (23-02-2022)“…Dental caries are a worldwide endemic chronic disease affecting people of all ages. Due to the limitations of daily used oral hygiene products, there is an…”
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Identification of transmembrane helix 1 (TM1) surfaces important for EnvZ dimerisation and signal output
Published in Biochimica et biophysica acta (01-08-2016)“…The Escherichia coli sensor kinase EnvZ modulates porin expression in response to various stimuli, including extracellular osmolarity, the presence of procaine…”
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Tuning Chemoreceptor Signaling by Positioning Aromatic Residues at the Lipid-Aqueous Interface
Published in Methods in molecular biology (Clifton, N.J.) (2018)“…Aromatic tuning facilitates stimulus-independent modulation of receptor output. The methodology is based upon the affinity of amphipathic aromatic residues,…”
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Differential repositioning of the second transmembrane helices from E. coli Tar and EnvZ upon moving the flanking aromatic residues
Published in Biochimica et biophysica acta (01-02-2015)“…Aromatic tuning, i.e. repositioning aromatic residues found at the cytoplasmic end of transmembrane (TM) domains within bacterial receptors, has been…”
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The Residue Composition of the Aromatic Anchor of the Second Transmembrane Helix Determines the Signaling Properties of the Aspartate/Maltose Chemoreceptor Tar of Escherichia coli
Published in Biochemistry (Easton) (06-03-2012)“…Repositioning of the tandem aromatic residues (Trp-209 and Tyr-210) at the cytoplasmic end of the second transmembrane helix (TM2) modulates the signal output…”
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Employing aromatic tuning to modulate output from two-component signaling circuits
Published in Journal of biological engineering (16-05-2015)“…Two-component signaling circuits (TCSs) govern the majority of environmental, pathogenic and industrial processes undertaken by bacteria. Therefore,…”
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Residues at the cytoplasmic end of transmembrane helix 2 determine the signal output of the TarEc chemoreceptor
Published in Biochemistry (Easton) (23-04-2013)“…Baseline signal output and communication between the periplasmic and cytoplasmic domains of the Escherichia coli aspartate chemoreceptor Tar(Ec) are both…”
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A Modular High-Throughput In Vivo Screening Platform Based on Chimeric Bacterial Receptors
Published in ACS synthetic biology (21-07-2017)“…Multidrug resistance (MDR) is a globally relevant problem that requires novel approaches. Two-component systems are a promising, yet untapped target for novel…”
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Structural characterization of AS1–membrane interactions from a subset of HAMP domains
Published in Biochimica et biophysica acta (01-10-2011)“…HAMP domains convert an extracellular sensory input into an intracellular signaling response in a wide variety of membrane-embedded bacterial proteins. These…”
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Mutational Analysis of the Transmembrane Helix 2-HAMP Domain Connection in the Escherichia coli Aspartate Chemoreceptor Tar
Published in Journal of Bacteriology (01-01-2011)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Comparative Phenotypic, Proteomic, and Phosphoproteomic Analysis Reveals Different Roles of Serine/Threonine Phosphatase and Kinase in the Growth, Cell Division, and Pathogenicity of Streptococcus suis
Published in Microorganisms (Basel) (26-11-2021)“…Eukaryote-like serine/threonine kinases (STKs) and cognate phosphatases (STPs) comprise an important regulatory system in many bacterial pathogens. The…”
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Residues at the Cytoplasmic End of Transmembrane Helix 2 Determine the Signal Output of the Tar Ec Chemoreceptor
Published in Biochemistry (Easton) (23-04-2013)“…Baseline signal output and communication between the periplasmic and cytoplasmic domains of the Escherichia coli aspartate chemoreceptor Tar Ec are both…”
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CheZ Phosphatase Localizes to Chemoreceptor Patches via CheA-Short
Published in Journal of Bacteriology (01-04-2003)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Production of human tetraspanin proteins in Escherichia coli
Published in Protein expression and purification (01-04-2012)“…► Seventeen integral membrane human tetraspanins were screened for expression in Escherichia coli. ► Detergents for solubilization were screened using…”
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