Search Results - "Dragos Peptanariu"
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Synergistic Effect of Low Molecular Weight Polyethylenimine and Polyethylene Glycol Components in Dynamic Nonviral Vector Structure, Toxicity, and Transfection Efficiency
Published in Molecules (Basel, Switzerland) (12-04-2019)“…When studying polyethylenimine derivatives as nonviral vectors for gene delivery, among the important issues to be addressed are high toxicity, low…”
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2
Novel Nanotherapeutic Systems Based on PEGylated Squalene Micelles for Enhanced In Vitro Activity of Methotrexate and Cytarabine
Published in Polymers (01-10-2023)“…Nanomedicine has garnered significant attention due to the advantages it offers in the treatment of cancer-related disorders, some of the deadliest diseases…”
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3
Mucoadhesive Mesoporous Silica Particles as Versatile Carriers for Doxorubicin Delivery in Cancer Therapy
Published in International journal of molecular sciences (01-10-2023)“…Due to their structural, morphological, and behavioral characteristics (e.g., large volume and adjustable pore size, wide functionalization possibilities,…”
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4
Towards Regenerative Audiology: Immune Modulation of Adipose-Derived Mesenchymal Cells Preconditioned with Citric Acid-Coated Antioxidant-Functionalized Magnetic Nanoparticles
Published in Medicina (Kaunas, Lithuania) (01-03-2023)“…: Based on stem cells, bioactive molecules and supportive structures, regenerative medicine (RM) is promising for its potential impact on field of hearing loss…”
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5
Functionalized Mesoporous Silica as Doxorubicin Carriers and Cytotoxicity Boosters
Published in Nanomaterials (Basel, Switzerland) (26-05-2022)“…Mesoporous silica nanoparticles (MSNs) bearing methyl, thiol or glucose groups were synthesized, and their encapsulation and release behaviors for the…”
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Chemical Attachment of 5-Nitrosalicylaldimine Motif to Silatrane Resulting in an Organic-Inorganic Structure with High Medicinal Significance
Published in Pharmaceutics (01-12-2022)“…Two chemical motifs of interest for medicinal chemistry, silatrane as 1-(3-aminopropyl) silatrane (SIL M), and nitro group attached in position 5 to…”
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Cytotoxic substituted indolizines as new colchicine site tubulin polymerisation inhibitors
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2020)“…A potential microtubule destabilising series of new indolizine derivatives was synthesised and tested for their anticancer activity against a panel of 60 human…”
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The Cytotoxic Properties of Some Tricyclic 1,3-Dithiolium Flavonoids
Published in Molecules (Basel, Switzerland) (04-07-2019)“…Due to the emergence of multidrug resistant microorganisms, new classes of antibiotics are needed. In this paper, we present the cytotoxic effects of five…”
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Hydroxypropyl Cellulose/Pluronic-Based Composite Hydrogels as Biodegradable Mucoadhesive Scaffolds for Tissue Engineering
Published in Gels (01-08-2022)“…Recently, the development of new materials with the desired characteristics for functional tissue engineering, ensuring tissue architecture and supporting…”
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Biocompatible Chitosan-Based Hydrogels for Bioabsorbable Wound Dressings
Published in Gels (10-02-2022)“…Supramolecular hydrogels based on chitosan and monoaldehydes are biomaterials with high potential for a multitude of bioapplications. This is due to the proper…”
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In Vitro and In Vivo Antioxidant Activity of the New Magnetic-Cerium Oxide Nanoconjugates
Published in Nanomaterials (Basel, Switzerland) (04-11-2019)“…Cerium oxide nanoparticles present the mimetic activity of superoxide dismutase, being able to inactivate the excess of reactive oxygen species (ROS)…”
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Biocompatible Self-Assembled Hydrogen-Bonded Gels Based on Natural Deep Eutectic Solvents and Hydroxypropyl Cellulose with Strong Antimicrobial Activity
Published in Gels (01-10-2022)“…Natural deep eutectic solvents (NADES)-hydroxypropyl cellulose (HPC) self-assembled gels with potential for pharmaceutical applications are prepared. FT-IR,…”
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13
Enhancing Flucytosine Anticandidal Activity Using PEGylated Squalene Nanocarrier
Published in ChemMedChem (06-09-2024)“…There is an emerging necessity for improved therapies against Candida-related infections, with significant implications for global healthcare. Current…”
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14
In situ CaCO3 mineralization controlled by carbonate source within chitosan-based cryogels
Published in Materials chemistry and physics (01-11-2021)“…Designing of multifunctional hydrogel/CaCO3 composites has received great interest in the modern tissue engineering. Herein, four chitosan-based cryogel…”
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Hydrophobic Composites Designed by a Nonwoven Cellulose-Based Material and Polymer/CaCO3 Patterns with Biomedical Applications
Published in Biomacromolecules (10-01-2022)“…Herein, we report a simple method to obtain hydrophobic surfaces by surface modification with calcium carbonate via diffusion-controlled crystallization using…”
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DyNAvectors: dynamic constitutional vectors for adaptive DNA transfection
Published in Chemical communications (Cambridge, England) (01-01-2015)“…Dynamic constitutional frameworks, based on squalene, PEG and PEI components, reversibly connected to core centers, allow the efficient identification of…”
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Hydrophobic Composites Designed by a Nonwoven Cellulose-Based Material and Polymer/CaCO 3 Patterns with Biomedical Applications
Published in Biomacromolecules (10-01-2022)“…Herein, we report a simple method to obtain hydrophobic surfaces by surface modification with calcium carbonate via diffusion-controlled crystallization using…”
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18
Biosynthesis of dextran by Weissella confusa and its In vitro functional characteristics
Published in International journal of biological macromolecules (01-02-2018)“…The aim of this study was to monitor the influence of the fermentation conditions on the exopolysaccharides (EPS) biosynthesis. For this, different culture…”
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Synthesis, structural characterization and biological studies of new Schiff bases containing trimethylsilyl groups
Published in Journal of molecular structure (05-01-2019)“…Two Schiff bases derived from 3-formylsalicilyc acid have been prepared by conventional condensation with trimethylsilyl-methyl-p-aminobenzoate and…”
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Multilayer gold nanoparticles as non-viral vectors for targeting MCF-7 cancer cells
Published in Biomaterials advances (01-01-2023)“…Cargocomplexes play a vital role in non-viral delivery methods due to their capacity to target certain cells (or cells through the cell-division cycle) and…”
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