Search Results - "Dragon, Julie"

Metagenomic analysis of Aedes aegypti and Culex quinquefasciatus mosquitoes from Grenada, West Indies by Ramos-Nino, Maria E, Fitzpatrick, Daniel M, Eckstrom, Korin M, Tighe, Scott, Hattaway, Lindsey M, Hsueh, Andy N, Stone, Diana M, Dragon, Julie A, Cheetham, Sonia

“…The mosquitoes Aedes aegypti (Linnaeus, 1762) (Diptera: Culicidae) and Culex quinquefasciatus Say, 1823 (Diptera: Culicidae) are two major vectors of…”
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Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step by Bruce, Emily A, Huang, Meei-Li, Perchetti, Garrett A, Tighe, Scott, Laaguiby, Pheobe, Hoffman, Jessica J, Gerrard, Diana L, Nalla, Arun K, Wei, Yulun, Greninger, Alexander L, Diehl, Sean A, Shirley, David J, Leonard, Debra G B, Huston, Christopher D, Kirkpatrick, Beth D, Dragon, Julie A, Crothers, Jessica W, Jerome, Keith R, Botten, Jason W

“…The ongoing COVID-19 pandemic has created an unprecedented need for rapid diagnostic testing. The World Health Organization (WHO) recommends a standard assay…”
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Perfluoroalkyl Substances (PFAS) Affect Inflammation in Lung Cells and Tissues by Dragon, Julie, Hoaglund, Michael, Badireddy, Appala Raju, Nielsen, Greylin, Schlezinger, Jennifer, Shukla, Arti

“…Adverse lung outcomes from exposure to per-and polyfluoroalkyl substances (PFAS) are known; however, the mechanism of action is poorly understood. To explore…”
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Unique Structural Features of Mammalian NEIL2 DNA Glycosylase Prime Its Activity for Diverse DNA Substrates and Environments by Eckenroth, Brian E., Cao, Vy Bao, Averill, April M., Dragon, Julie A., Doublié, Sylvie

“…Oxidative damage on DNA arising from both endogenous and exogenous sources can result in base modifications that promote errors in replication as well as…”
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Caught in motion: human NTHL1 undergoes interdomain rearrangement necessary for catalysis by Carroll, Brittany L, Zahn, Karl E, Hanley, John P, Wallace, Susan S, Dragon, Julie A, Doublié, Sylvie

“…Abstract Base excision repair (BER) is the main pathway protecting cells from the continuous damage to DNA inflicted by reactive oxygen species. BER is…”
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The Y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease by Case, Laure K, Wall, Emma H, Dragon, Julie A, Saligrama, Naresha, Krementsov, Dimitry N, Moussawi, Mohamad, Zachary, James F, Huber, Sally A, Blankenhorn, Elizabeth P, Teuscher, Cory

“…Understanding the DNA elements that constitute and control the regulatory genome is critical for the appropriate therapeutic management of complex diseases…”
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The Intrinsic Activity of Thyroxine Is Critical for Survival and Growth and Regulates Gene Expression in Neonatal Liver by Galton, Valerie Anne, Martinez, Maria Elena, Dragon, Julie A, St Germain, Donald L, Hernandez, Arturo

“…Thyroxine (T4) is generally considered to be a prohormone that requires conversion to triiodothyronine (T3) to exert biological activity. Although evidence…”
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Critical Role for SLAM/SAP Signaling in the Thymic Developmental Programming of IL-17- and IFN-γ-Producing γδ T Cells by Dienz, Oliver, DeVault, Victoria L, Musial, Shawn C, Mistri, Somen K, Mei, Linda, Baraev, Aleksandr, Dragon, Julie A, Krementsov, Dimitry, Veillette, Andre, Boyson, Jonathan E

“…During thymic development, mouse γδ T cells commit to either an IFN-γ- or an IL-17-producing phenotype through mechanisms that remain unclear. In this study,…”
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Immunotranscriptomic profiling the acute and clearance phases of a human challenge dengue virus serotype 2 infection model by Hanley, John P., Tu, Huy A., Dragon, Julie A., Dickson, Dorothy M., Rio-Guerra, Roxana del, Tighe, Scott W., Eckstrom, Korin M., Selig, Nicholas, Scarpino, Samuel V., Whitehead, Stephen S., Durbin, Anna P., Pierce, Kristen K., Kirkpatrick, Beth D., Rizzo, Donna M., Frietze, Seth, Diehl, Sean A.

“…About 20–25% of dengue virus (DENV) infections become symptomatic ranging from self-limiting fever to shock. Immune gene expression changes during progression…”
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Targeting the fatty acid binding proteins disrupts multiple myeloma cell cycle progression and MYC signaling by Farrell, Mariah, Fairfield, Heather, Karam, Michelle, D'Amico, Anastasia, Murphy, Connor S, Falank, Carolyne, Pistofidi, Romanos Sklavenitis, Cao, Amanda, Marinac, Catherine R, Dragon, Julie A, McGuinness, Lauren, Gartner, Carlos G, Iorio, Reagan Di, Jachimowicz, Edward, DeMambro, Victoria, Vary, Calvin, Reagan, Michaela R

“…Multiple myeloma is an incurable plasma cell malignancy with only a 53% 5-year survival rate. There is a critical need to find new multiple myeloma…”
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The Neural Progenitor Cell-Associated Transcription Factor FoxG1 Regulates Cardiac Epicardial Cell Proliferation by Pilcher, Lucy, Solomon, Lara, Dragon, Julie A., Gupta, Dhananjay, Spees, Jeffrey L.

“…The epicardium is a layer of mesothelial cells that covers the surface of the heart. During development, epicardial cells undergo epithelial-to-mesenchymal…”
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Sex-specific control of central nervous system autoimmunity by p38 mitogen-activated protein kinase signaling in myeloid cells by Krementsov, Dimitry N., Noubade, Rajkumar, Dragon, Julie A., Otsu, Kinya, Rincon, Mercedes, Teuscher, Cory

“…Objective Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS), characterized by a global increasing…”
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Base Excision Repair Variants in Cancer by Marsden, Carolyn G, Dragon, Julie A, Wallace, Susan S, Sweasy, Joann B

“…Base excision repair (BER) is a key genome maintenance pathway that removes endogenously damaged DNA bases that arise in cells at very high levels on a daily…”
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Targeting the fatty acid binding proteins disrupts multiple myeloma cell cycle progression and MYC signalin by Farrell, Mariah, Fairfield, Heather, Karam, Michelle, D'Amico, Anastasia, Murphy, Connor S, Falank, Carolyne, Pistofidi, Romanos Sklavenitis, Cao, Amanda, Marinac, Catherine R, Dragon, Julie A, McGuinness, Lauren, Gartner, Carlos G, Iorio, Reagan Di, Jachimowicz, Edward, DeMambro, Victoria, Vary, Calvin, Reagan, Michaela R

“…Multiple myeloma is an incurable plasma cell malignancy with only a 53% 5-year survival rate. There is a critical need to find new multiple myeloma…”
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Left Ventricular Gene Expression in Heart Failure With Preserved Ejection Fraction—Profibrotic and Proinflammatory Pathways and Genes by Ye, Bo, Bradshaw, Amy D., Abrahante, Juan E., Dragon, Julie A., Häußler, Tim N., Bell, Stephen P., Hirashima, Fuyuki, LeWinter, Martin, Zile, Michael R., Meyer, Markus

“…Heart failure with preserved ejection fraction (HFpEF) is increasingly prevalent and has few treatments. The molecular mechanisms and resultant signaling…”
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Unique Transcriptomic Changes Underlie Hormonal Interactions During Mammary Histomorphogenesis in Female Pigs by Trott, Josephine F, Schennink, Anke, Horigan, Katherine C, Lemay, Danielle G, Cohen, Julia R, Famula, Thomas R, Dragon, Julie A, Hovey, Russell C

“…Successful lactation and the risk for developing breast cancer depend on growth and differentiation of the mammary gland (MG) epithelium that is regulated by…”
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Sex-specific signaling through Toll-Like Receptors 2 and 4 contributes to survival outcome of Coxsackievirus B3 infection in C57Bl/6 mice by Roberts, Brian J, Dragon, Julie A, Moussawi, Mohamad, Huber, Sally A

“…Coxsackievirus B3 (CVB3) induces myocarditis, an inflammatory heart disease, which affects men more than women. Toll-like receptor (TLR) signaling has been…”
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Life and its traces in Antarctica's McMurdo Dry Valley paleolakes: a survey of preservation by Greenfield, Samuel R., Tighe, Scott W., Bai, Yu, Goerlitz, David S., Von Turkovich, Michele, Taatjes, Douglas J., Dragon, Julie A., Johnson, Sarah Stewart

“…•Scanning electron microscopy reveals possible nanobacteria in the McMurdo Dry Valley.•Moss long extinct from the region imaged via light and scanning electron…”
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Copy number variation in Y chromosome multicopy genes is linked to a paternal parent-of-origin effect on CNS autoimmune disease in female offspring by Case, Laure K, Wall, Emma H, Osmanski, Erin E, Dragon, Julie A, Saligrama, Naresha, Zachary, James F, Lemos, Bernardo, Blankenhorn, Elizabeth P, Teuscher, Cory

“…The prevalence of some autoimmune diseases is greater in females compared with males, although disease severity is often greater in males. The reason for this…”
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High prevalence of Phasi Charoen-like virus from wild-caught Aedes aegypti in Grenada, W.I. as revealed by metagenomic analysis by Ramos-Nino, Maria E, Fitzpatrick, Daniel M, Tighe, Scott, Eckstrom, Korin M, Hattaway, Lindsey M, Hsueh, Andy N, Stone, Diana M, Dragon, Julie, Cheetham, Sonia

“…Arboviruses cause diseases of significant global health concerns. Interactions between mosquitoes and their microbiota as well as the important role of this…”
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