Search Results - "Dragavon, Joan"

Validation and verification of the Abbott RealTime SARS-CoV-2 assay analytical and clinical performance by Degli-Angeli, Emily, Dragavon, Joan, Huang, Meei-Li, Lucic, Danijela, Cloherty, Gavin, Jerome, Keith R., Greninger, Alexander L., Coombs, Robert W.

“…•The expected 100 copies/mL LOD reported in the EUA Abbott RealTime SARS-CoV-2 assay product insert was exceeded.•All clinical samples positive for 24…”
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Emergence of SARS-CoV-2 escape mutations during Bamlanivimab therapy in a phase II randomized clinical trial by Choudhary, Manish C., Chew, Kara W., Deo, Rinki, Flynn, James P., Regan, James, Crain, Charles R., Moser, Carlee, Hughes, Michael D., Ritz, Justin, Ribeiro, Ruy M., Ke, Ruian, Dragavon, Joan A., Javan, Arzhang Cyrus, Nirula, Ajay, Klekotka, Paul, Greninger, Alexander L., Fletcher, Courtney V., Daar, Eric S., Wohl, David A., Eron, Joseph J., Currier, Judith S., Parikh, Urvi M., Sieg, Scott F., Perelson, Alan S., Coombs, Robert W., Smith, Davey M., Li, Jonathan Z.

“…SARS-CoV-2 mutations that cause resistance to monoclonal antibody (mAb) therapy have been reported. However, it remains unclear whether in vivo emergence of…”
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Infectious Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Virus in Symptomatic Coronavirus Disease 2019 (COVID-19) Outpatients: Host, Disease, and Viral Correlates by Mollan, Katie R, Eron, Joseph J, Krajewski, Taylor J, Painter, Wendy, Duke, Elizabeth R, Morse, Caryn G, Goecker, Erin A, Premkumar, Lakshmanane, Wolfe, Cameron R, Szewczyk, Laura J, Alabanza, Paul L, Loftis, Amy James, Degli-Angeli, Emily J, Brown, Ariane J, Dragavon, Joan A, Won, John J, Keys, Jessica, Hudgens, Michael G, Fang, Lei, Wohl, David A, Cohen, Myron S, Baric, Ralph S, Coombs, Robert W, Sheahan, Timothy P, Fischer, William A

“…Abstract Background Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectious virus isolation in outpatients with coronavirus disease…”
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HIV-1 Nucleic Acids Identify Rectal HIV Exposures in Self-Collected Rectal Swabs, Whereas Y-Chromosome Single Tandem Repeat Mixtures Are Not Reliable Biomarkers of Condomless Receptive Anal Intercourse by Lemos, Maria P., Nandi, Vijay, Dragavon, Joan, Fleming, Ira, Krishnan, Keertana, Musuruana, Martin, Kramer, Madeline, Glantz, Hayley, Andrasik, Michele, Coombs, Robert W., McElrath, M. Juliana, Tieu, Hong-Van

“…To focus interventions, biomarkers of HIV-1 exposure could help in identifying subpopulations at highest risk of acquisition. We assessed whether Y-chromosome…”
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Development and Validation of a Genotypic Assay to Quantify CXCR4- and CCR5-Tropic Human Immunodeficiency Virus Type-1 (HIV-1) Populations and a Comparison to Trofile by Ko, Daisy, McLaughlin, Sherry, Deng, Wenjie, Mullins, James I, Dragavon, Joan, Harb, Socorro, Coombs, Robert W, Frenkel, Lisa M

“…HIV-1 typically infects cells via the CD4 receptor and CCR5 or CXCR4 co-receptors. Maraviroc is a CCR5-specific viral entry inhibitor; knowledge of viral…”
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Novel Criteria for Diagnosing Acute and Early Human Immunodeficiency Virus Infection in a Multinational Study of Early Antiretroviral Therapy Initiation by Crowell, Trevor A, Ritz, Justin, Coombs, Robert W, Zheng, Lu, Eron, Joseph J, Mellors, John W, Dragavon, Joan, van Zyl, Gert U, Lama, Javier R, Ruxrungtham, Kiat, Grinsztejn, Beatriz, Arduino, Roberto C, Fox, Lawrence, Ananworanich, Jintanat, Daar, Eric S

“…Antiretroviral therapy (ART) initiation during acute and early human immunodeficiency virus infection (AEHI) limits HIV reservoir formation and may facilitate…”
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Relative accuracy of serum, whole blood, and oral fluid HIV tests among Seattle men who have sex with men by Stekler, Joanne D, O’Neal, Joshua D, Lane, Aric, Swanson, Fred, Maenza, Janine, Stevens, Claire E, Coombs, Robert W, Dragavon, Joan A, Swenson, Paul D, Golden, Matthew R, Branson, Bernard M

“…Abstract Background Point-of-care (POC) rapid HIV tests have sensitivity during the “window period” comparable only to earliest generation EIAs. To date, it is…”
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Performance of an alternative HIV diagnostic algorithm using the ARCHITECT HIV Ag/Ab Combo assay and potential utility of sample-to-cutoff ratio to discriminate primary from established infection by Ramos, Eric M, Harb, Socorro, Dragavon, Joan, Swenson, Paul, Stekler, Joanne D, Coombs, Robert W

“…Abstract Background The ARCHITECT HIV Ag/Ab Combo assay has a wide dynamic range for determining the sample-to-cutoff ratio (S/CO) values compared to other…”
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HIV-1 RNA may decline more slowly in semen than in blood following initiation of efavirenz-based antiretroviral therapy by Graham, Susan M, Holte, Sarah E, Dragavon, Joan A, Ramko, Kelly M, Mandaliya, Kishor N, McClelland, R Scott, Peshu, Norbert M, Sanders, Eduard J, Krieger, John N, Coombs, Robert W

“…Antiretroviral therapy (ART) decreases HIV-1 RNA levels in semen and reduces sexual transmission from HIV-1-infected men. Our objective was to study the time…”
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Validation for clinical use of a novel HIV-2 plasma RNA viral load assay using the Abbott m2000 platform by Chang, Ming, Gottlieb, Geoffrey S, Dragavon, Joan A, Cherne, Stephen L, Kenney, Donna L, Hawes, Stephen E, Smith, Robert A, Kiviat, Nancy B, Sow, Papa Salif, Coombs, Robert W

“…Abstract Background Optimal care of persons infected with human immunodeficiency virus type 2 (HIV-2) requires an accurate assessment of HIV-2 plasma viral…”
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Human Immunodeficiency Viruses Appear Compartmentalized to the Female Genital Tract in Cross-Sectional Analyses but Genital Lineages Do Not Persist Over Time by Bull, Marta E., Heath, Laura M., McKernan-Mullin, Jennifer L., Kraft, Kelli M., Acevedo, Luis, Hitti, Jane E., Cohn, Susan E., Tapia, Kenneth A., Holte, Sarah E., Dragavon, Joan A., Coombs, Robert W., Mullins, James I., Frenkel, Lisa M.

“…Background. Whether unique human immunodeficiency type 1 (HIV) genotypes occur in the genital tract is important for vaccine development and management of drug…”
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Compartmentalization of HIV-1 within the female genital tract is due to monotypic and low-diversity variants not distinct viral populations by Bull, Marta, Learn, Gerald, Genowati, Indira, McKernan, Jennifer, Hitti, Jane, Lockhart, David, Tapia, Kenneth, Holte, Sarah, Dragavon, Joan, Coombs, Robert, Mullins, James, Frenkel, Lisa

“…Compartmentalization of HIV-1 between the genital tract and blood was noted in half of 57 women included in 12 studies primarily using cell-free virus. To…”
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Monoclonal antibody treatment drives rapid culture conversion in SARS-CoV-2 infection by Boucau, Julie, Chew, Kara W., Choudhary, Manish, Deo, Rinki, Regan, James, Flynn, James P., Crain, Charles R., Hughes, Michael D., Ritz, Justin, Moser, Carlee, Dragavon, Joan A., Javan, Arzhang C., Nirula, Ajay, Klekotka, Paul, Greninger, Alexander L., Coombs, Robert W., Fischer, William A., Daar, Eric S., Wohl, David A., Eron, Joseph J., Currier, Judith S., Smith, Davey M., Li, Jonathan Z., Barczak, Amy K.

“…SARS-CoV-2 monoclonal antibodies (mAbs) are among the treatments recommended for high-risk ambulatory persons with COVID-19. Here, we study viral culture…”
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Monotypic Human Immunodeficiency Virus Type 1 Genotypes across the Uterine Cervix and in Blood Suggest Proliferation of Cells with Provirus by BULL, Marta E, LEARN, Gerald H, MCELHONE, Scott, HITTI, Jane, LOCKHART, David, HOLTE, Sarah, DRAGAVON, Joan, COOMBS, Robert W, MULLINS, James I, FRENKEL, Lisa M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Silibinin inhibits HIV-1 infection by reducing cellular activation and proliferation by McClure, Janela, Lovelace, Erica S, Elahi, Shokrollah, Maurice, Nicholas J, Wagoner, Jessica, Dragavon, Joan, Mittler, John E, Kraft, Zane, Stamatatos, Leonidas, Stamatatos, Leonidis, Horton, Helen, De Rosa, Stephen C, Coombs, Robert W, Polyak, Stephen J

“…Purified silymarin-derived natural products from the milk thistle plant (Silybum marianum) block hepatitis C virus (HCV) infection and inhibit T cell…”
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Effect of Highly Active Antiretroviral Therapy on Viral Burden in the Lungs of HIV-Infected Subjects by Twigg, Homer L., Weiden, Michael, Valentine, Fred, Bick, Carol T. Schnizlein, Bassett, Roland, Zheng, Lu, Wheat, Joseph, Day, Richard B., Rominger, Helen, Collman, Ronald G., Fox, Lawrence, Brizz, Barbara, Dragavon, Joan, Coombs, Robert W., Bucy, R. Pat

“…Background. Human immunodeficiency virus (HIV) is readily detectable in the lungs of infected subjects and leads to an accumulation of CD8+ lymphocytes in the…”
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Post-prostatic massage fluid/urine as an alternative to semen for studying male genitourinary HIV-1 shedding by Graham, Susan M, Krieger, John N, Githua, Peter L M, Wamuyu, Lorraine W, Wale, Steven, Ramko, Kelly M, Dragavon, Joan A, Muller, Charles H, Holte, Sarah E, Mandaliya, Kishor N, McClelland, R Scott, Peshu, Norbert M, Sanders, Eduard J, Coombs, Robert W

“…Genitourinary tract samples are required to investigate male HIV-1 infectivity. Because semen collection is often impractical, the acceptability, feasibility…”
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A Randomized, Placebo-Controlled Trial of the Quadrivalent Human Papillomavirus Vaccine in Human Immunodeficiency Virus-Infected Adults Aged 27 Years or Older: AIDS Clinical Trials Group Protocol A5298 by Wilkin, Timothy J, Chen, Huichao, Cespedes, Michelle S, Leon-Cruz, Jorge T, Godfrey, Catherine, Chiao, Elizabeth Y, Bastow, Barbara, Webster-Cyriaque, Jennifer, Feng, Qinghua, Dragavon, Joan, Coombs, Robert W, Presti, Rachel M, Saah, Alfred, Cranston, Ross D

“…Anal cancer is common in human immunodeficiency virus-infected adults. This randomized trial did not find a benefit from human papillomavirus (HPV) vaccination…”
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The effect of oral preexposure prophylaxis on the progression of HIV-1 seroconversion by Donnell, Deborah, Ramos, Eric, Celum, Connie, Baeten, Jared, Dragavon, Joan, Tappero, Jordan, Lingappa, Jairam R, Ronald, Allan, Fife, Kenneth, Coombs, Robert W

“…OBJECTIVE:To investigate whether oral preexposure prophylaxis (PrEP) alters timing and patterns of seroconversion when PrEP use continues after HIV-1…”
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Selective Decay of Intact HIV-1 Proviral DNA on Antiretroviral Therapy by Gandhi, Rajesh T, Cyktor, Joshua C, Bosch, Ronald J, Mar, Hanna, Laird, Gregory M, Martin, Albine, Collier, Ann C, Riddler, Sharon A, Macatangay, Bernard J, Rinaldo, Charles R, Eron, Joseph J, Siliciano, Janet D, McMahon, Deborah K, Mellors, John W

“…Abstract Background HIV-1 proviruses persist in people on antiretroviral therapy (ART) but most are defective and do not constitute a replication-competent…”
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