Search Results - "Drachman, D"
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Statins and the risk of dementia
Published in The Lancet (British edition) (11-11-2000)“…Dementia affects an estimated 10% of the population older than 65 years. Because vascular and lipid-related mechanisms are thought to have a role in the…”
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Mycophenolate mofetil : A safe and promising immunosuppressant in neuromuscular diseases
Published in Neurology (09-01-2001)“…The authors report the use mycophenolate mofetil (MM) in the treatment of neuromuscular diseases. Thirty-eight patients (32 with MG, three with inflammatory…”
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Ataxia associated with Hashimoto's disease: progressive non-familial adult onset cerebellar degeneration with autoimmune thyroiditis
Published in Journal of neurology, neurosurgery and psychiatry (01-07-2001)“…Acquired cerebellar ataxia has been described with hypothyroidism, and is typically reversible by thyroid hormone replacement therapy. The cerebellar…”
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Novel VCP mutations in inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia
Published in Clinical genetics (01-11-2007)“…Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia (IBMPFD, OMIM 167320) has recently been attributed to eight missense…”
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Myasthenia Gravis
Published in The New England journal of medicine (23-06-1994)“…Twenty years ago, the discovery of a deficit of acetylcholine receptors at the neuromuscular junctions of patients with myasthenia gravis 1 and the development…”
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Head drop and camptocormia
Published in Journal of neurology, neurosurgery and psychiatry (01-07-2002)“…Table 1 Neuromuscular causes for head ptosis Site of pathology Disorders Motor neuron Amyotrophic lateral sclerosis 1, 2 Postpolio syndrome 3 Peripheral nerve…”
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85 Optic Nerve Ultrasound in the Hypertensive Patient
Published in Annals of emergency medicine (2011)Get full text
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Specific immunotherapy of experimental myasthenia gravis in vitro and in vivo : The Guided Missile strategy
Published in Journal of neuroimmunology (15-10-2012)“…Abstract Current immunotherapy of myasthenia gravis (MG) is often effective, but entails risks of infection and neoplasia. The “Guided Missile” strategy…”
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Granzyme B: Evidence for a role in the origin of myasthenia gravis
Published in Journal of neuroimmunology (15-09-2008)“…Abstract Purpose of research Although the pathogenesis of myasthenia gravis (MG) as an antibody mediated disorder of acetylcholine receptors (AChRs) at…”
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Expression of heat shock proteins in Alzheimer's disease
Published in Neurology (01-03-1991)“…In an investigation of heat shock proteins (HSPs) in the brains of Alzheimer's disease (AD) patients and cognitively intact control subjects, we found that 2…”
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Familial Alzheimer's disease: Site of mutation influences clinical phenotype
Published in Annals of neurology (01-09-2000)“…Alzheimer's disease (AD) is caused by multiple genetic and/or environmental etiologies. Because differences in the genetically determined pathogenesis may…”
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Cerebral Thromboembolism: Value of Susceptibility-Weighted Imaging in the Initial Diagnosis of Acute Infarction
Published in The neuroradiology journal (01-02-2012)“…Susceptibility-weighted imaging (SWI) is commonly used to diagnose cerebral hemorrhage, calcification, and other T2* lesions. Its role in the detection of…”
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Occam's razor, geriatric syndromes, and the dizzy patient
Published in Annals of internal medicine (07-03-2000)Get full text
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Neointimal thickening after stent delivery of paclitaxel: change in composition and arrest of growth over six months
Published in Journal of the American College of Cardiology (01-12-2000)“…OBJECTIVES The purpose of this study was to determine long-term effects of stent-based paclitaxel delivery on amount, rate and composition of neointimal…”
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Aging and the brain: a new frontier
Published in Annals of neurology (01-12-1997)“…With aging, both "normal" senescent age-related changes (ARCs) and late-onset diseases affect the brain, producing declines in performance. The brain as a…”
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Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis
Published in Annals of neurology (01-07-1990)“…Recently, the excitatory amino acid neurotransmitter glutamate was implicated in the pathogenesis of a variety of chronic degenerative neurological diseases in…”
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Alzheimer's disease: what is it, how many people have it, and why do we need to know?
Published in Neurology (25-07-2000)Get full text
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Familial and sporadic Alzheimer's disease : Neuropathology cannot exclude a final common pathway
Published in Neurology (01-02-1996)“…Whether all etiologic forms of Alzheimer's disease (AD) share a final common pathway is a major issue. We determined the severity and regional distribution of…”
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Inhibition of cyclooxygenase-2 protects motor neurons in an organotypic model of amyotrophic lateral sclerosis
Published in Annals of neurology (01-11-2000)“…The pathogenesis of motor neuron loss in amyotrophic lateral sclerosis (ALS) is thought to involve both glutamate‐mediated excitotoxicity and oxidative damage…”
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