Search Results - "Drachenberg, Cinthia B"
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The Banff Working Group Classification of Definitive Polyomavirus Nephropathy: Morphologic Definitions and Clinical Correlations
Published in Journal of the American Society of Nephrology (01-02-2018)“…Polyomavirus nephropathy (PVN) is a common viral infection of renal allografts, with biopsy-proven incidence of approximately 5%. A generally accepted…”
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Pathologic Classification of Diabetic Nephropathy
Published in Journal of the American Society of Nephrology (01-04-2010)“…Although pathologic classifications exist for several renal diseases, including IgA nephropathy, focal segmental glomerulosclerosis, and lupus nephritis, a…”
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Differential expression of M3 muscarinic receptors in progressive colon neoplasia and metastasis
Published in Oncotarget (28-03-2017)“…M3 muscarinic receptor (M3R) activation promotes colon cancer cell proliferation, migration, and invasion in vitro. Although over-expression of CHRM3, the gene…”
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Muscarinic receptor agonist-induced βPix binding to β-catenin promotes colon neoplasia
Published in Scientific reports (07-10-2023)“…M 3 muscarinic receptors (M 3 R) modulate β-catenin signaling and colon neoplasia. CDC42/RAC guanine nucleotide exchange factor, βPix, binds to β-catenin in…”
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SARS-CoV-2 ORF3a induces COVID-19-associated kidney injury through HMGB1-mediated cytokine production
Published in mBio (30-09-2024)“…The primary challenge posed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is COVID-19-related mortality, often exacerbated by…”
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BK virus–associated urinary bladder carcinoma in transplant recipients: report of 2 cases, review of the literature, and proposed pathogenetic model
Published in Human pathology (01-05-2013)“…Summary Despite strong experimental evidence, BK polyomavirus involvement in human cancers has been controversial. We report 2 cases of kidney ± pancreas…”
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BK Polyomavirus Evades Innate Immune Sensing by Disrupting the Mitochondrial Network and Promotes Mitophagy
Published in iScience (24-07-2020)“…Immune escape contributes to viral persistence, yet little is known about human polyomaviruses. BK-polyomavirus (BKPyV) asymptomatically infects 90% of humans…”
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Epidemiology and Pathophysiology of Glomerular C4d Staining in Native Kidney Biopsies
Published in Kidney international reports (01-11-2019)“…Routine C4d staining in renal transplantation has stimulated its use in kidney biopsies with glomerulonephritis (GN). Methodical description on staining…”
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Tubulocystic carcinoma of the kidney: a histologic, immunohistochemical, and ultrastructural study
Published in Virchows Archiv : an international journal of pathology (01-05-2013)“…Tubulocystic carcinoma of the kidney (TCCK) is a tumor entity, which is not yet included in the WHO classification of renal tumors. The histogenesis of this…”
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Tubular Epithelial and Peritubular Capillary Endothelial Injury in COVID-19 AKI
Published in Kidney international reports (01-02-2021)Get full text
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Zinc finger protein 277 is an intestinal transit-amplifying cell marker and colon cancer oncogene
Published in JCI insight (22-02-2022)“…Sustained proliferative signaling and resisting cell death are hallmarks of cancer. Zinc finger protein 277 (ZNF277; murine Zfp277), a transcription factor…”
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Divergent effects of muscarinic receptor subtype gene ablation on murine colon tumorigenesis reveals association of M3R and zinc finger protein 277 expression in colon neoplasia
Published in Molecular cancer (03-04-2014)“…M3 and M1 subtype muscarinic receptors are co-expressed in normal and neoplastic intestinal epithelial cells. In mice, ablating Chrm3, the gene encoding M3R,…”
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An Initial Analysis of the Baseline Levels of Dd-cfDNA After Pancreas Transplantation: A Prospective Study From High-volume Centers in the United States
Published in Transplantation direct (01-04-2023)“…Pancreas transplantation offers patients with diabetes an opportunity for glucose homeostasis. Current blood tests to surveil for rejection have poor…”
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Clinical course of polyoma virus nephropathy in 67 renal transplant patients
Published in Journal of the American Society of Nephrology (01-08-2002)“…Polyoma virus (PV) can cause interstitial nephritis and lead to graft failure in renal transplant recipients. The clinical course of patients with polyoma…”
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Causes of Renal Allograft Injury in Recipients With Normal Donor-derived Cell-free DNA
Published in Transplantation direct (01-04-2021)“…Donor-derived cell-free DNA (dd-cfDNA) is a noninvasive biomarker for the early detection of organ transplant rejection and other causes of graft injury. For…”
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Is the Duodenum Trustworthy?
Published in Transplantation (01-03-2019)Get full text
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Bedside to Bench: Role of Muscarinic Receptor Activation in Ultrarapid Growth of Colorectal Cancer in a Patient With Pheochromocytoma
Published in Mayo Clinic proceedings (01-11-2013)“…Abstract An elderly man with long-standing, nonresectable pheochromocytoma had rapid development of rectal adenocarcinoma despite close endoscopic…”
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Histologic versus Molecular Diagnosis of BK Polyomavirus–Associated Nephropathy: A Shifting Paradigm?
Published in Clinical journal of the American Society of Nephrology (01-05-2006)“…Although discovered in 1970 the BK virus infections had no significant clinical impact until the emergence of BK virus-associated allograft nephropathy…”
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Farnesoid X receptor represses matrix metalloproteinase 7 expression, revealing this regulatory axis as a promising therapeutic target in colon cancer
Published in The Journal of biological chemistry (24-05-2019)“…The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily of bile acid–activated transcription factors and an important regulator of cell…”
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Lesson of the Month: perinephric myxoid pseudotumor of fat co‐occurring with polycystic kidney disease
Published in Histopathology (01-09-2024)Get full text
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