Search Results - "Dröge, M J"

Virodhamine and CP55,940 modulate cAMP production and IL‐8 release in human bronchial epithelial cells by Gkoumassi, E, Dekkers, B G J, Dröge, M J, Elzinga, C R S, Schmidt, M, Meurs, H, Zaagsma, J, Nelemans, S A

“…Background and purpose: We investigated expression of cannabinoid receptors and the effects of the endogenous cannabinoid virodhamine and the synthetic agonist…”
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Systemic Absorption of Rifamycin SV MMX Administered as Modified-Release Tablets in Healthy Volunteers by Di Stefano, A F D, Rusca, A, Loprete, L, Dröge, M J, Moro, L, Assandri, A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Paralogous gene analysis reveals a highly enantioselective 1,2‐O‐isopropylideneglycerol caprylate esterase of Bacillus subtilis by Dröge, Melloney J., Bos, Rein, Quax, Wim J.

“…Carboxylesterase NP of Bacillus subtilis Thai I‐8, characterized in 1992 as a very enantioselective (S)‐naproxen esterase, was found to show no…”
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The fatty-acid-induced conformational states of human serum albumin investigated by means of multiple co-binding of protons and oleic acid by Dröge, J H, Janssen, L H, Wilting, J

“…The binding of oleic acid to human serum albumin causes progressive changes in (a) the pK of some amino acid residues, as detected by pH-stat titration and (b)…”
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Directed Evolution of Bacillus subtilis Lipase A by Use of Enantiomeric Phosphonate Inhibitors: Crystal Structures and Phage Display Selection by Dröge, Melloney J, Boersma, Ykelien L, van Pouderoyen, Gertie, Vrenken, Titia E, Rüggeberg, Carsten J, Reetz, Manfred T, Dijkstra, Bauke W, Quax, Wim J

“…Phage display can be used as a protein-engineering tool for the selection of proteins with desirable binding properties from a library of mutants. Here we…”
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Extracellular lipases from Bacillus subtilis: regulation of gene expression and enzyme activity by amino acid supply and external pH by Eggert, Thorsten, Brockmeier, Ulf, Dröge, Melloney J, Quax, Wim J, Jaeger, Karl-Erich

“…Bacillus subtilis secretes two lipases LipA and LipB into the culture medium. Both enzyme genes were differentially expressed depending on the growth…”
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Immobilization of chiral enzyme inhibitors on solid supports by amide-forming coupling and olefin metathesis by Reetz, Manfred T, Rüggeberg, Carsten J, Dröge, Melloney J, Quax, Wim J

“…The question whether phage display can be used as a selection method in the directed evolution of enantioselective enzymes has not been answered satisfactorily…”
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Comparison and functional characterisation of three homologous intracellular carboxylesterases of Bacillus subtilis by Dröge, Melloney J., Bos, Rein, Boersma, Ykelien L., Quax, Wim J.

“…Enzymatic hydrolysis of racemic mixtures may provide an attractive method for the enantiopure production of chiral pharmaceuticals. For example, the…”
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Arachidonic acid mediates non-capacitative calcium entry evoked by CB1-cannabinoid receptor activation in DDT1 MF-2 smooth muscle cells by Demuth, Dirk G., Gkoumassi, Effimia, Dröge, Melloney J., Dekkers, Bart G.J., Esselink, Henk J., van Ree, Rutger M., Parsons, Mike E., Zaagsma, Johan, Molleman, Areles, Nelemans, S. Ad

“…Cannabinoid CB1‐receptor stimulation in DDT1 MF‐2 smooth muscle cells induces a rise in [Ca2+]i, which is dependent on extracellular Ca2+ and modulated by…”
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Binding of phage displayed Bacillus subtilis lipase A to a phosphonate suicide inhibitor by DRÖGE, Melloney J, RÜGGEBERG, Carsten J, VAN DER SLOOT, Almer M, SCHIMMEL, Judith, DIJKSTRA, Dolf Swaving, VERHAERT, Raymond M. D, REETZ, Manfred T, QUAX, Wim J

“…Phage display can be used as a protein engineering tool to select proteins with desirable binding properties from a library of randomly constructed mutants…”
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Chiral gas chromatography for the determination of 1,2-O-isopropylidene-sn-glycerol stereoisomers by Dröge, Melloney J., Bos, Rein, Woerdenbag, Herman J., Quax, Wim J.

“…A stereospecific gas chromatography (GC) method using a (6‐O‐t butyldimethylsilyl‐2,3‐di‐O‐methyl)‐β‐cyclodextrin as the chiral stationary phase has been…”
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Alternative splicing of cyclooxygenase-1 mRNA in the human iris by Dröge, Melloney J, van Sorge, Adriaan A, van Haeringen, Nicolaas J, Quax, Wim J, Zaagsma, Johan

“…In homogenates of the human iris, the nonsteroidal anti-inflammatory drug (NSAID) S(+)flurbiprofen has been reported to inhibit cyclooxygenase-1 (COX-1)…”
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Allosteric properties of the oxyphenbutazone--human serum albumin complex by Dröge, J H, Janssen, L H, Wilting, J

“…The conformational change of albumin which occurs around physiological pH, the so-called N-B transition, has been studied by measuring the induced circular…”
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Evidence for the fatty acid-induced heterogeneity of the N and B conformations of human serum albumin by Dröge, J H, Janssen, L H, Wilting, J

“…The influence of oleic acid on the interaction between albumin and warfarin, oxyphenbutazone or diazepam has been studied by circular dichroism and equilibrium…”
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The pH dependence of the thermodynamics of the interaction of diazepam with human serum albumin by Janssen, L H, Dröge, J H, Durlinger, F C, Fruytier, F J

“…The heat effect associated with the binding of diazepam to human serum albumin has been measured from pH 5.5 to 9.5 using flow microcalorimetry. The number of…”
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A study on the allosteric interaction between the major binding sites of human serum albumin using microcalorimetry by Dröge, J H, Janssen, L H, Wilting, J

“…The binding of warfarin and oxyphenbutazone to albumin has been studied at pH 6.8 and pH 9.2 by measuring the heat of binding of these ligands to their…”
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