Search Results - "Dráber, Petr"

Gold nanoparticle-based immuno-PCR for detection of tau protein in cerebrospinal fluid by Stegurová, Lucie, Dráberová, Eduarda, Bartos, Ales, Dráber, Pavel, Řípová, Daniela, Dráber, Petr

“…Tau protein in cerebrospinal fluid (CSF) is an important biomarker of Alzheimer's disease and some other brain diseases. Enzyme-linked immunosorbent assays…”
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Rapid and sensitive detection of cytokines using functionalized gold nanoparticle-based immuno-PCR, comparison with immuno-PCR and ELISA by Potůčková, Lucie, Franko, Filip, Bambousková, Monika, Dráber, Petr

“…Reliable and simple methods are required for detection of low concentrations of cytokines and some other proteins in complex biological fluids. This is…”
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Membrane-cytoskeleton dynamics in the course of mast cell activation by Dráber, Pavel, Dráber, Petr

“…Aggregation of the high-affinity IgE receptor (FcεRI) on the plasma membrane of mast cells and basophils initiates signaling events leading to a rapid release…”
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Down-regulation of Protein-tyrosine Phosphatases Activates an Immune Receptor in the Absence of Its Translocation into Lipid Rafts by Heneberg, Petr, Dráberová, Lubica, Bambousková, Monika, Pompach, Petr, Dráber, Petr

“…The earliest known biochemical step that occurs after ligand binding to the multichain immune recognition receptor is tyrosine phosphorylation of the receptor…”
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What precedes the initial tyrosine phosphorylation of the high affinity IgE receptor in antigen-activated mast cell? by Bugajev, Viktor, Bambousková, Monika, Dráberová, Lubica, Dráber, Petr

“…An interaction of multivalent antigen with its IgE bound to the high-affinity IgE receptor (FcεRI) on the surface of mast cells or basophils initiates a series…”
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Non-apoptotic Phosphatidylserine Externalization Induced by Engagement of Glycosylphosphatidylinositol-anchored Proteins by Smrz, Daniel, Dráberová, L'ubica, Dráber, Petr

“…The exposure of phosphatidylserine (PS) on the cell surface is a general marker of apoptotic cells. Non-apoptotic PS externalization is induced by several…”
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Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL by Volná, Petra, Lebduska, Pavel, Dráberová, Lubica, Símová, Sárka, Heneberg, Petr, Boubelík, Michael, Bugajev, Viktor, Malissen, Bernard, Wilson, Bridget S, Horejsí, Václav, Malissen, Marie, Dráber, Petr

“…Engagement of the Fcepsilon receptor I (FcepsilonRI) on mast cells and basophils initiates signaling pathways leading to degranulation. Early activation events…”
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STIM1-directed reorganization of microtubules in activated mast cells by Hájková, Zuzana, Bugajev, Viktor, Dráberová, Eduarda, Vinopal, Stanislav, Dráberová, Lubica, Janáček, Jiří, Dráber, Petr, Dráber, Pavel

“…Activation of mast cells by aggregation of the high-affinity IgE receptors (FcεRI) initiates signaling events leading to the release of inflammatory and…”
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Cross-talk between Tetraspanin CD9 and Transmembrane Adaptor Protein Non-T Cell Activation Linker (NTAL) in Mast Cell Activation and Chemotaxis by Hálová, Ivana, Dráberová, Lubica, Bambousková, Monika, Machyna, Martin, Stegurová, Lucie, Smrž, Daniel, Dráber, Petr

“…Chemotaxis, a process leading to movement of cells toward increasing concentrations of chemoattractants, is essential, among others, for recruitment of mast…”
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The transmembrane adaptor protein NTAL signals to mast cell cytoskeleton via the small GTPase Rho by Tůmová, Magda, Koffer, Anna, Šimíček, Michal, Dráberová, Lubica, Dráber, Petr

“…The transmembrane adaptor protein NTAL (non‐T‐cell activation linker) participates in signalosome assembly in hematopoietic cells, but its exact role in cell…”
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Regulation of microtubule formation in activated mast cells by complexes of gamma-tubulin with Fyn and Syk kinases by Sulimenko, Vadym, Dráberová, Eduarda, Sulimenko, Tetyana, Macurek, Libor, Richterová, Vera, Dráber, Petr, Dráber, Pavel

“…Aggregation of the high-affinity IgE receptors (FcepsilonRIs) on the surface of granulated mast cells initiates a chain of signaling events culminating in the…”
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1,2-propanediol-trehalose mixture as a potent quantitative real-time PCR enhancer by Horáková, Helena, Polakovičová, Iva, Shaik, Gouse M, Eitler, Jiří, Bugajev, Viktor, Dráberová, Lubica, Dráber, Petr

“…Quantitative real-time PCR (qPCR) is becoming increasingly important for DNA genotyping and gene expression analysis. For continuous monitoring of the…”
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Quantification of α-tubulin isotypes by sandwich ELISA with signal amplification through biotinyl-tyramide or immuno-PCR by Dráberová, Eduarda, Stegurová, Lucie, Sulimenko, Vadym, Hájková, Zuzana, Dráber, Petr, Dráber, Pavel

“…Microtubules formed by αβ-tubulin dimers represent cellular structures that are indispensable for the maintenance of cell morphology and for cell motility…”
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Vacuolin-1-modulated exocytosis and cell resealing in mast cells by Shaik, Gouse M., Dráberová, Lubica, Heneberg, Petr, Dráber, Petr

“…The small chemical vacuolin-1 induces rapid formation of large vacuoles in various cell types. In epithelial cells, vacuolin-1 has been shown to inhibit Ca 2+…”
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Engagement of Phospholipid Scramblase 1 in Activated Cells: IMPLICATION FOR PHOSPHATIDYLSERINE EXTERNALIZATION AND EXOCYTOSIS by Smrž, Daniel, Lebduška, Pavel, Dráberová, L'ubica, Korb, Jan, Dráber, Petr

“…Phosphatidylserine (PS) in quiescent cells is predominantly confined to the inner leaflet of the plasma membrane. Externalization of PS is a marker of…”
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Regulation of Ca2+ Signaling in Mast Cells by Tyrosine-Phosphorylated and Unphosphorylated Non-T Cell Activation Linker by Draberova, Lubica, Shaik, Gouse Mohiddin, Volna, Petra, Heneberg, Petr, Tumova, Magda, Lebduska, Pavel, Korb, Jan, Draber, Petr

“…Engagement of the FcepsilonRI in mast cells and basophils leads to a rapid tyrosine phosphorylation of the transmembrane adaptors LAT (linker for activation of…”
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Involvement of filamentous actin in setting the threshold for degranulation in mast cells by Tolarová, Helena, Dráberová, Lubica, Heneberg, Petr, Dráber, Petr

“…Previous studies using cytochalasins and latrunculin B, inhibitors of actin polymerization, showed that filamentous (F)‐actin had a negative regulatory role in…”
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Signal transduction and chemotaxis in mast cells by Draber, Petr, Halova, Ivana, Polakovicova, Iva, Kawakami, Toshiaki

“…Mast cells play crucial roles in both innate and adaptive arms of the immune system. Along with basophils, mast cells are essential effector cells for allergic…”
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Positive and Negative Signals in Mast Cell Activation by Bulfone-Paus, Silvia, Nilsson, Gunnar, Draber, Petr, Blank, Ulrich, Levi-Schaffer, Francesca

“…Mast cells are powerful immune modulators of the tissue microenvironment. Within seconds of activation, these cells release a variety of preformed biologically…”
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Simplified PCR-Based Quantification of Proteins with DNA Aptamers and Methylcellulose as a Blocking Agent by Redcenko, Oleksij, Tumova, Magda, Draber, Petr

“…Due to their unique three-dimensional structure, DNA or RNA oligonucleotide aptamers bind to various molecules with high affinity and specificity. Aptamers,…”
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