Search Results - "Doyle, S A"

Role of a Conserved Glutamine Residue in Tuning the Catalytic Activity of Escherichia coli Cytochrome c Nitrite Reductase by Clarke, Thomas A, Kemp, Gemma L, Wonderen, Jessica H. Van, Doyle, Rose-Marie A. S, Cole, Jeffrey A, Tovell, Nick, Cheesman, Myles R, Butt, Julea N, Richardson, David J, Hemmings, Andrew M

“…The pentaheme cytochrome c nitrite reductase (NrfA) of Escherichia coli is responsible for nitrite reduction during anaerobic respiration when nitrate is…”
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Assessment of the cost-effectiveness of Australia's risk-sharing agreement for direct-acting antiviral treatments for hepatitis C: a modelling study by Scott, Dr Nick, Palmer, Ms Anna, Tidhar, Mr Tom, Stoove, Prof Mark, Sacks-Davis, Dr Rachel, Doyle, A/Prof Joseph S., Pedrana, Dr Alisa, Thompson, Prof Alexander J., Wilson, Prof David P., Hellard, Prof Margaret

“…Hepatitis C elimination may be possible with broad uptake of direct-acting antiviral treatments (DAAs). In 2016 the Australian government committed A$1.2…”
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Redesigning the Substrate Specificity of an Enzyme:  Isocitrate Dehydrogenase by Doyle, Sharon A, Fung, Siu-Yue F, Koshland, Daniel E

“…Despite the structural similarities between isocitrate and isopropylmalate, isocitrate dehydrogenase (IDH) exhibits a strong preference for its natural…”
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Global partnerships are critical to advance the control of Neglected Zoonotic Diseases: The case of the Global Alliance for Rabies Control by Nel, Louis H., Taylor, Louise H., Balaram, Deepashree, Doyle, Kim A.S.

“…[Display omitted] •The Global Alliance for Rabies Control (GARC) is the only NGO dedicated to improving rabies control.•GARC founded the Partners for Rabies…”
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Synthetic nonpsychotropic cannabinoids with potent antiinflammatory, analgesic, and leukocyte antiadhesion activities by Burstein, Sumner H, Audette, Charlene A, Breuer, Aviva, Devane, William A, Colodner, Sharona, Doyle, Sharon A, Mechoulam, Raphael

“…Two strategies for the design of therapeutically useful cannabinoids have been combined to produce compounds with greatly increased antiinflammatory activity…”
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A combinatorial approach to modeling imperfect coverage by Doyle, S.A., Dugan, J.B., Patterson-Hine, F.A.

“…A new algorithm combines a coverage model with a combinatorial model to compute system unreliability. Its advantage is that for a class of computer systems, it…”
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Antagonism to the actions of platelet activating factor by a nonpsychoactive cannabinoid by Burstein, S H, Audette, C A, Doyle, S A, Hull, K, Hunter, S A, Latham, V

“…A recent report from our laboratory gave evidence showing that tetrahydrocannabinol (THC)-7-oic acid has antinociceptive activity in the mouse. We also pointed…”
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Expression of the G glycoprotein gene of human respiratory syncytial virus in Salmonella typhimurium by Martin-Gallardo, Antonia, Fleischer, Edward, Doyle, Shawn A, Arumugham, Rasappa, Collins, Peter L, Hildreth, Stephen W, Paradiso, Peter R

“…1 Department of Virology, Praxis Biologics Inc., 300 East River Road, Rochester, New York 14623 and 2 Laboratory of Infectious Diseases, National Institute of…”
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World Rabies Day - a decade of raising awareness by Balaram, Deepashree, Taylor, Louise H, Doyle, Kim A S, Davidson, Elizabeth, Nel, Louis H

“…World Rabies Day was set up in 2007 to raise global awareness about rabies, to provide information on how to prevent the disease in at-risk communities and…”
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A Saturation Screen for Cis-Acting Regulatory DNA in the Hox Genes of Ciona intestinalis by Keys, David N., Lee, Byung-in, Di Gregorio, Anna, Harafuji, Naoe, Detter, J. Chris, Wang, Mei, Kahsai, Orsalem, Ahn, Sylvia, Zhang, Cindy, Doyle, Sharon A., Satoh, Noriyuki, Satou, Yutaka, Saiga, Hidetoshi, Christian, Allen T., Rokhsar, Dan S., Hawkins, Trevor L., Levine, Mike, Richardson, Paul M.

“…A screen for the systematic identification of cis-regulatory elements within large (> 100 kb) genomic domains containing Hox genes was performed by using the…”
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Detection of cannabinoid receptors by photoaffinity labelling by Burstein, S H, Audette, C A, Charalambous, A, Doyle, S A, Guo, Y, Hunter, S A, Makriyannis, A

“…A novel [125I]-labelled photoaffinity ligand designed to detect cannabinoid binding sites has been used in mouse brain preparations and in cultured S49 mouse…”
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G-protein mediation of cannabinoid-induced phospholipase activation by Audette, C A, Burstein, S H, Doyle, S A, Hunter, S A

“…The release of arachidonic acid from mouse peritoneal and S49 cells induced by delta 1-tetrahydrocannabinol was found to be altered by prior exposure of the…”
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The effect of carbonic anhydrase inhibitors and other drugs on sodium entry to cerebrospinal fluid by Vogh, B P, Doyle, A S

“…Single cerebrospinal fluid (CSF) samples, taken 7 min after the i.v. administration of tracer 22Na+, provided data for calculation of rate constants for entry…”
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Structural Basis for a Change in Substrate Specificity:  Crystal Structure of S113E Isocitrate Dehydrogenase in a Complex with Isopropylmalate, Mg2+, and NADP by Doyle, Sharon A, Beernink, Peter T, Koshland, Daniel E

“…Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate and has negligible activity toward other (R)-malate-type substrates. The…”
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Contrasting catalytic profiles of multiheme nitrite reductases containing CxxCK heme-binding motifs by Doyle, Rose-Marie A. S., Marritt, Sophie J., Gwyer, James D., Lowe, Thomas G., Tikhonova, Tamara V., Popov, Vladimir O., Cheesman, Myles R., Butt, Julea N.

“…The multiheme cytochromes from Thioalkalivibrio nitratireducens (TvNiR) and Escherichia coli (EcNrfA) reduce nitrite to ammonium. Both enzymes contain…”
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Characterization of Recombinant Human Aldolase B and Purification by Metal Chelate Chromatography by Doyle, S.A., Tolan, D.R.

“…Recombinant human aldolase B and the native enzyme purified from human liver were found to be identical in size, charge, structure, Km constants for…”
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An improved method for the in vitro evolution of aptamers and applications in protein detection and purification by Murphy, Michael B., Fuller, Shirin T., Richardson, Paul M., Doyle, Sharon A.

“…One of the key components of proteomics initiatives is the production of high affinity ligands or probes that specifically recognize protein targets in assays…”
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Summer clinical experience for nursing students by Doyle, S A

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A sharing of daily routine at SL/TCH/THI (St. Luke's, Texas Children's Hospital, Texas Heart Institute) by Doyle, S A

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Fatal disseminated cryptococcosis and concurrent ehrlichiosis in a dog by Collett, M G, Doyle, A S, Reyers, F, Kruse, T, Fabian, B

“…Laboratory findings in an adult bull terrier presented with a history of anorexia and weight loss included the following: severe anaemia, leukocytosis,…”
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