Search Results - "Doyle, S"
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The Synthesis and Assembly of Polymeric Microparticles Using Microfluidics
Published in Advanced materials (Weinheim) (06-11-2009)“…The controlled synthesis of micrometer‐sized polymeric particles bearing features such as nonspherical shapes and spatially segregated chemical properties is…”
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2
Complex DNA knots detected with a nanopore sensor
Published in Nature communications (02-10-2019)“…Equilibrium knots are common in biological polymers—their prevalence, size distribution, structure, and dynamics have been extensively studied, with…”
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3
Thermoresponsive nanoemulsion-based gel synthesized through a low-energy process
Published in Nature communications (21-06-2019)“…Thermoresponsive nanoemulsions find utility in applications ranging from food to pharmaceuticals to consumer products. Prior systems have found limited…”
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4
The global diversity of Haemonchus contortus is shaped by human intervention and climate
Published in Nature communications (22-10-2019)“…Haemonchus contortus is a haematophagous parasitic nematode of veterinary interest. We have performed a survey of its genome-wide diversity using single-worm…”
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Effect of YOYO-1 on the mechanical properties of DNA
Published in Soft matter (28-12-2014)“…YOYO-1 is a green fluorescent dye which is widely used to image single DNA molecules in solution for biophysical studies. However, the question of whether the…”
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6
Static and Dynamic Errors in Particle Tracking Microrheology
Published in Biophysical journal (01-01-2005)“…Particle tracking techniques are often used to assess the local mechanical properties of cells and biological fluids. The extracted trajectories are exploited…”
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7
The polymer physics of single DNA confined in nanochannels
Published in Advances in colloid and interface science (01-06-2016)“…In recent years, applications and experimental studies of DNA in nanochannels have stimulated the investigation of the polymer physics of DNA in confinement…”
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8
Multifunctional Encoded Particles for High-Throughput Biomolecule Analysis
Published in Science (American Association for the Advancement of Science) (09-03-2007)“…High-throughput screening for genetic analysis, combinatorial chemistry, and clinical diagnostics benefits from multiplexing, which allows for the simultaneous…”
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Compression and self-entanglement of single DNA molecules under uniform electric field
Published in Proceedings of the National Academy of Sciences - PNAS (27-09-2011)“…We experimentally study the effects of a uniform electric field on the conformation of single DNA molecules. We demonstrate that a moderate electric field…”
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10
A Boosted Bayesian Multiresolution Classifier for Prostate Cancer Detection From Digitized Needle Biopsies
Published in IEEE transactions on biomedical engineering (01-05-2012)“…Diagnosis of prostate cancer (CaP) currently involves examining tissue samples for CaP presence and extent via a microscope, a time-consuming and subjective…”
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A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef
Published in Nutrition journal (10-03-2010)“…Growing consumer interest in grass-fed beef products has raised a number of questions with regard to the perceived differences in nutritional quality between…”
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12
Subtelomeric plasticity contributes to gene family expansion in the human parasitic flatworm Schistosoma mansoni
Published in BMC genomics (27-02-2024)“…The genomic region that lies between the telomere and chromosome body, termed the subtelomere, is heterochromatic, repeat-rich, and frequently undergoes…”
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Noninvasive monitoring of single-cell mechanics by acoustic scattering
Published in Nature methods (01-03-2019)“…The monitoring of mechanics in a single cell throughout the cell cycle has been hampered by the invasiveness of mechanical measurements. Here we quantify…”
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Current status and future of genomics in fetal and maternal medicine: A scientific review commissioned by European Board and College of Obstetrics and Gynaecology (EBCOG)
Published in European journal of obstetrics & gynecology and reproductive biology (01-08-2024)“…This EBCOG guidance reviews the current and future status of genomics within fetal and maternal medicine. This document addresses the clinical uses of genetic…”
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Two distinct overstretched DNA structures revealed by single-molecule thermodynamics measurements
Published in Proceedings of the National Academy of Sciences - PNAS (22-05-2012)“…Double-stranded DNA is a dynamic molecule whose structure can change depending on conditions. While there is consensus in the literature about many structures…”
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Measuring the impact of oesophagectomy on physical functioning and physical activity participation: a prospective study
Published in BMC cancer (12-07-2019)“…Oesophagectomy remains the only curative intervention for oesophageal cancer, with defined nutritional and health-related quality of life (HR-QOL)…”
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17
Comparisons of a Polymer in Confinement versus Applied Force
Published in Macromolecules (13-08-2013)“…The similarities and differences between geometric and tensile constraints on polymers have not been fully investigated. Here we use theory (blob models) and…”
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Continuous-flow lithography for high-throughput microparticle synthesis
Published in Nature materials (01-05-2006)“…Precisely shaped polymeric particles and structures are widely used for applications in photonic materials, MEMS, biomaterials and self-assembly. Current…”
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Sarcopenia during neoadjuvant therapy for oesophageal cancer: characterising the impact on muscle strength and physical performance
Published in Supportive care in cancer (01-05-2018)“…Purpose Preoperative chemo(radio)therapy for oesophageal cancer (OC) may have an attritional impact on body composition and functional status, impacting…”
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Stretching self-entangled DNA molecules in elongational fields
Published in Soft matter (28-04-2015)“…We present experiments of self-entangled DNA molecules stretching under a planar elongational field, and their stretching dynamics are compared to identical…”
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