Search Results - "Doyle, Kelly"

Targeting Anti-TGF- β Therapy to Fibrotic Kidneys with a Dual Specificity Antibody Approach by McGaraughty, Steve, Davis-Taber, Rachel A, Zhu, Chang Z, Cole, Todd B, Nikkel, Arthur L, Chhaya, Meha, Doyle, Kelly J, Olson, Lauren M, Preston, Gregory M, Grinnell, Christine M, Salte, Katherine M, Giamis, Anthony M, Luo, Yanping, Sun, Victor, Goodearl, Andrew D, Gopalakrishnan, Murali, Lacy, Susan E

“…Targeted delivery of a therapeutic agent to a site of pathology to ameliorate disease while limiting exposure at undesired tissues is an aspirational treatment…”
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Short-term oral gavage administration of adenine induces a model of fibrotic kidney disease in rats by Zhu, Chang Z., Doyle, Kelly J., Nikkel, Arthur L., Olsen, Lauren, Namovic, Marian T., Salte, Katherine, Widomski, Deborah, Su, Zhi, Donnelly-Roberts, Diana L., Gopalakrishnan, Murali M., McGaraughty, Steve

“…The adenine model of kidney disease typically involves dietary delivery of adenine over several weeks. This model can be variable in its disease progression…”
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Mutant Huntingtin Impairs Axonal Trafficking in Mammalian Neurons In Vivo and In Vitro by Trushina, Eugenia, Dyer, Roy B, Badger, 2nd, John D, Ure, Daren, Eide, Lars, Tran, David D, Vrieze, Brent T, Legendre-Guillemin, Valerie, McPherson, Peter S, Mandavilli, Bhaskar S, Van Houten, Bennett, Zeitlin, Scott, McNiven, Mark, Aebersold, Ruedi, Hayden, Michael, Parisi, Joseph E, Seeberg, Erling, Dragatsis, Ioannis, Doyle, Kelly, Bender, Anna, Chacko, Celin, McMurray, Cynthia T

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Comparison of two chromogranin A assays and investigation of nonlinear specimens by Erickson, J. Alan, Chiang, Fang-I, Walker, Chelsie M., Genzen, Jonathan R., Doyle, Kelly

“…As a marker for functional and non-functional neuroendocrine tumors, serum chromogranin A (CgA) concentrations have shown value for detecting and monitoring…”
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Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients by Yuda, Junichiro, Will, Christine, Phillips, Darren C., Abraham, Linu, Alvey, Cory, Avigdor, Abraham, Buck, Wayne, Besenhofer, Lauren, Boghaert, Erwin, Cheng, Dong, Cojocari, Dan, Doyle, Kelly, Hansen, T. Matthew, Huang, Kevin, Johnson, Eric F., Judd, Andrew S., Judge, Russell A., Kalvass, John C., Kunzer, Aaron, Lam, Lloyd T., Li, Rachel, Martin, Ruth L., Mastracchio, Anthony, Mitten, Mike, Petrich, Adam, Wang, Jin, Ward, James E., Zhang, Haichao, Wang, Xilu, Wolff, Johannes E., Bell-McGuinn, Katherine M., Souers, Andrew J.

“…Background MCL-1 is a prosurvival B-cell lymphoma 2 family protein that plays a critical role in tumor maintenance and survival and can act as a resistance…”
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Evaluation of a new venous catheter blood draw device and its impact on specimen hemolysis rates by Natali, Ruth, Wand, Cara, Doyle, Kelly, Noguez, Jaime H.

“…Blood collections from peripheral intravenous catheters offer several benefits to patients, including reduced needle punctures and patient discomfort, but they…”
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Commentary on Extreme Hyperglycemia in an Elderly Patient by Doyle, Kelly

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Parkin Function in Parkinson Disease by Doyle, Kelly

“…[...]structureactivity studies led to tyrosine kinase inhibitor imatinib for treating BCR/ABL positive chronic myeloid leukemia. [...]although sequence variant…”
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Oxidation of 2-Cys-peroxiredoxins by Arachidonic Acid Peroxide Metabolites of Lipoxygenases and Cyclooxygenase-2 by Cordray, Pauline, Doyle, Kelly, Edes, Kornelia, Moos, Philip J., Fitzpatrick, Frank A.

“…Human peroxiredoxins serve dual roles as anti-oxidants and regulators of H2O2-mediated cell signaling. The functional versatility of peroxiredoxins depends on…”
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Buffy coat removal to mitigate reporting false normal G6PD phenotype results in patients undergoing rasburicase therapy for tumor lysis syndrome by Mathewson, Nicole, Hunsaker, Joshua, Young, Brittany, Doyle, Kelly

“…Abstract Glucose-6-phosphate dehydrogenase (G6PD) is the primary source of NADPH in red blood cells (RBCs). NADPH reduces reactive oxygen species (ROS) thereby…”
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Gender Differences in Academic Ethics with Recommendations for Curricular Change by Miori, Virginia M, Doyle, Kelly A, Campbell, Kathleen

“…An extensive study has been performed on the importance of building ethical principles into secondary school and college curricula. In published surveys,…”
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Reference intervals: past, present, and future by Doyle, Kelly, Bunch, Dustin R.

“…Clinical laboratory test results alone are of little value in diagnosing, treating, and monitoring health conditions; as such, a clinically actionable cutoff…”
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Comparison of Heat Fractionation and Gel Electrophoresis Methods for the Quantitative Determination of Alkaline Phosphatase Isoenzymes by Balogun, Kayode, Lee, Megan, Doyle, Kelly

“…Abstract Introduction Alkaline phosphatase (ALP) is important in the diagnostic work-up for hepatobiliary and bone diseases. ALP isoenzymes are expressed in…”
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On-Cell Stability for Therapeutic Drug Monitoring by Nelson, Heather, Pearson, Lauren, Rudolf, Joseph, Doyle, Kelly

“…Abstract Introduction A common problem in many clinical laboratories and outpatient clinics is processing specimens rapidly to comply with specimen stability…”
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Verifying Clinically Derived Reference Intervals for Daily Excretion Rates of Fractionated Metanephrines Using Modern Indirect Reference Interval Models by Doyle, Kelly, Frank, Elizabeth L

“…Abstract Objectives Biochemical testing of urinary metanephrines is useful in the diagnosis and monitoring of pheochromocytoma and paragangliomas. We…”
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Capture the Tag: Mitigation of Biotin Interference in ELISA and Automated Immunoassays by Pre-Conjugating Biotinylated Antibodies to the Streptavidin Surface by Nelson, Heather, Doyle, Kelly, Laulu, Sonia, Lu, Jun

“…Abstract Introduction Streptavidin to biotin binding is one of the strongest non-covalent interactions in nature, and is therefore, successfully incorporated…”
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Abnormal Hb A1c Result from a Diabetic Patient Leads to Unexpected Diagnosis by Mathewson, Nicole J, Pearson, Lauren N, Doyle, Kelly

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Genetic biomarkers of sensitivity and resistance to venetoclax monotherapy in patients with relapsed acute myeloid leukemia by Chyla, Brenda, Daver, Naval, Doyle, Kelly, McKeegan, Evelyn, Huang, Xin, Ruvolo, Vivian, Wang, Zixing, Chen, Ken, Souers, Andrew, Leverson, Joel, Potluri, Jalaja, Boghaert, Erwin, Bhathena, Anahita, Konopleva, Marina, Popovic, Relja

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Establishment of NSE/Hgb Ratio to Address Hemolysis Interference in NSE Tumor Marker Assays by Kroner, Grace, La’ulu, Sonia, Doyle, Kelly

“…Abstract Neuron specific enolase (NSE) is a serum soluble tumor marker for certain neuroendocrine tumors and a marker of some types of brain trauma. Red blood…”
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Analytical and operational considerations of measuring glucose 6-phosphate dehydrogenase (G6PD) activity using a fully automated assay by Zilka, Sarah, Wei, Ruhan, Payto, Drew, Doyle, Kelly, Hockings, Jennifer, Colón-Franco, Jessica M

“…This study determined the performance characteristics of a quantitative glucose-6-phosphate dehydrogenase (G6PD) assay with automated lysis and evaluated the…”
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