Search Results - "Doyle, I R"

Relationship of anti-GM-CSF antibody concentration, surfactant protein A and B levels, and serum LDH to pulmonary parameters and response to GM-CSF therapy in patients with idiopathic alveolar proteinosis by Seymour, J F, Doyle, I R, Nakata, K, Presneill, J J, Schoch, O D, Hamano, E, Uchida, K, Fisher, R, Dunn, A R

“…Background: Conventional measures of the severity of alveolar proteinosis (AP) include alveolar-arterial oxygen gradient ([A – a]Do2), vital capacity (VC), and…”
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Serum levels of CC16, SP-A and SP-B reflect tobacco-smoke exposure in asymptomatic subjects by Robin, M, Dong, P, Hermans, C, Bernard, A, Bersten, A.D, Doyle, I.R

“…Since the 16-kDa bronchiolar Clara cell protein (CC16) and the alveolar surfactant-associated proteins (SP)-A and -B leak into the circulation when parenchymal…”
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Therapeutic efficacy of Granulocyte-Macrophage Colony-Stimulating Factor in patients with idiopathic acquired Alveolar Proteinosis by SEYMOUR, John F, PRESNEILL, Jeffrey J, PAIN, Michael C, DUNN, Ashley R, SCHOCH, Otto D, DOWNIE, Gordon H, MOORE, Paul E, DOYLE, Ian R, VINCENT, Janette M, NAKATA, Koh, KITAMURA, Takayuki, LANGTON, David

“…Alveolar proteinosis (AP) is characterized by excessive surfactant accumulation, and most cases are of unknown etiology. Standard therapy for AP is whole-lung…”
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Surfactant proteins-A and -B are elevated in plasma of patients with acute respiratory failure by DOYLE, I. R, BERSTEN, A. D, NICHOLAS, T. E

“…Surfactant protein-A (SP-A) leaks into the circulation of patients with acute respiratory distress syndrome (ARDS) or acute cardiogenic pulmonary edema (APE)…”
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Quantity and structure of surfactant proteins vary among patients with alveolar proteinosis by DOYLE, I. R, DAVIDSON, K. G, BARR, H. A, NICHOLAS, T. E, PAYNE, K, PFITZNER, J

“…Alveolar proteinosis (AP) is an idiopathic condition characterized by excess alveolar surfactant. Although the surfactant proteins (SP) are known to be…”
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Serum surfactant protein-A levels in patients with acute cardiogenic pulmonary edema and adult respiratory distress syndrome by Doyle, I R, Nicholas, T E, Bersten, A D

“…Detection of alveolo-capillary damage has important implications for treatment modalities in ventilated patients. Although surfactant protein-A (SP-A) is…”
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Clearance of clara cell secretory protein 16 (CC16) and surfactant proteins A and B from blood in acute respiratory failure by DOYLE, I. R, HERMANS, C, BERNARD, A, NICHOLAS, T. E, BERSTEN, A. D

“…Surfactant proteins A and B (SP-A and SP-B) enter the circulation in a manner that acutely reflects changes in pulmonary function in patients with acute…”
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Ultrastructural and protein analysis of surfactant in the Australian lungfish Neoceratodus forsteri: evidence for conservation of composition for 300 million years by Power, J H, Doyle, I R, Davidson, K, Nicholas, T E

“…The Australian lungfish Neoceratodus forsteri is the most primitive member of the lungfish family, with a surfactant lipid composition similar to the…”
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Measurement of tidal volume by using transthoracic impedance variations in rats by Davidson, K. G, Bersten, A. D, Nicholas, T. E, Ravenscroft, P. R, Doyle, I. R

“…1  Department of Human Physiology, School of Medicine, Flinders University of South Australia, and Departments of 2  Critical Care Medicine and 3  Biomedical…”
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Pulmonary alveolar proteinosis: two contrasting cases by Crocker, HL, Pfitzner, J, Doyle, IR, Hague, WM, Smith, BJ, Ruffin, RE

“…Pulmonary alveolar proteinosis is a rare condition characterized by the abnormal accumulation of surfactant‐like material within the alveolar spaces and distal…”
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Surfactant composition reflects lung overinflation and arterial oxygenation in patients with acute lung injury by Bersten, AD, Doyle, IR, Davidson, KG, Barr, HA, Nicholas, TE, Kermeen, F

“…Pulmonary surfactant abnormalities have consistently been documented in patients with acute lung injury (ALI), however, there is little evidence directly…”
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Elevated plasma surfactant protein-B predicts development of acute respiratory distress syndrome in patients with acute respiratory failure by BERSTEN, Andrew D, HUNT, Tamara, NICHOLAS, Terrence E, DOYLE, I. A. N. R

“…Surfactant protein-B is a lung specific protein secreted into the air spaces by pulmonary epithelial type II cells that leaks into the bloodstream in increased…”
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Surfactant replacement therapy in ARDS: white knight or noise in the system? by Nicholas, T E, Doyle, I R, Bersten, A D

“…Although one would predict that surfactant replacement therapy would be effective in acute respiratory distress syndrome (ARDS), a recent large trial proved…”
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Inclusion of proteins into calcium oxalate crystals precipitated from human urine: a highly selective phenomenon by Doyle, I R, Ryall, R L, Marshall, V R

“…The abundance of protein in the matrix of calcium oxalate uroliths has fueled speculation regarding its role in stone genesis. In this study, we wanted to…”
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Expression and distribution of surfactant proteins and lysozyme after prolonged hyperpnea by Yogalingam, G, Doyle, I R, Power, J H

“…We have induced prolonged hyperpnea in rats and examined the distribution of surfactant-associated proteins (SP-A and SP-B) and lysozyme in lamellar bodies…”
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ARDS: nothing new? by Bersten, Andrew D, Doyle, Ian R

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Differential changes in SP-A and disaturated phospholipids in the isolated perfused rat lung and in vivo by Doyle, I R, Barr, H A, Davidson, K G, Nicholas, T E

“…Alveolar disaturated phospholipids (DSPA) increase in vivo in rats with hyperpnea and in isolated perfused lungs (IPL) in response to either salbutamol or…”
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Plasma surfactant protein-B is elevated in infants with respiratory syncytial virus-induced bronchiolitis by WANG, S.-Z, DOYLE, I. R, NICHOLAS, T. E, FORSYTH, K. D

“…Respiratory syncytial virus (RSV) is the most frequent cause of bronchiolitis. However the pathophysiology of bronchiolitis is unclear. Leukocytes, especially…”
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Immunohistochemical distribution and quantification of crystal matrix protein by Stapleton, Alan M.F., Seymour, Anthony E., Brennan, James S., Doyle, Ian R., Marshall, Villis R., Ryall, Rosemary L.

“…Immunohistochemical distribution and quantification of crystal matrix protein. The aim of this study was to determine the immunohistochemical distribution and…”
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Distribution of surfactant protein A in rat lung by Doyle, I R, Barr, H A, Nicholas, T E

“…Although surfactant protein A (SP-A) is an integral component of alveolar surfactant, its relative abundance in lamellar bodies, regarded as the intracellular…”
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