Search Results - "Doyle, Glenn A.R."

The Structural Basis for the Elastolytic Activity of the 92-kDa and 72-kDa Gelatinases by Shipley, J. Michael, Doyle, Glenn A.R., Fliszar, Catherine J., Ye, Qi-Zhuang, Johnson, Linda L., Shapiro, Steven D., Welgus, Howard G., Senior, Robert M.

“…Several matrix metalloproteinases, including the 92-kDa and 72-kDa gelatinases, macrophage metalloelastase (MME), and matrilysin degrade insoluble elastin…”
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The c-myc coding region determinant-binding protein: a member of a family of KH domain RNA-binding proteins by Doyle, Glenn A. R., Leeds, Peter F., Fleisig, Ani J., Ross, Jeff, Betz, Natalie A., Prokipcak, Rebecca D.

“…The half-life of c-myc mRNA is regulated when cells change their growth rates or differentiate. Two regions within c-myc mRNA determine its short half-life…”
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The structural basis for the elastolytic activity of the 92-kDa and 72-kDa gelatinases. Role of the fibronectin type II-like repeats by Shipley, J M, Doyle, G A, Fliszar, C J, Ye, Q Z, Johnson, L L, Shapiro, S D, Welgus, H G, Senior, R M

“…Several matrix metalloproteinases, including the 92-kDa and 72-kDa gelatinases, macrophage metalloelastase (MME), and matrilysin degrade insoluble elastin…”
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Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site by Doyle, G A, Pierce, R A, Parks, W C

“…In this report, we demonstrate that the AP-1 site and a distal promoter element regulate transcriptional induction of collagenase-1 during monocytic…”
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Distinct Mechanisms Regulate TIMP-1 Expression at Different Stages of Phorbol Ester-Mediated Differentiation of U937 Cells by Doyle, Glenn A. R, Saarialho-Kere, Ulpu K, Parks, William C

“…Upon exposure to 12-O-tetradecanoylphorbol 13-acetate (PMA), promonocyte-like U937 cells differentiate into macrophage-like cells and begin to express certain…”
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Molecular mechanisms regulating the production of collagenase and TIMP in U937 cells: Evidence for involvement of delayed transcriptional activation and enhanced mRNA stability by Shapiro, Steven D, Doyle, Glenn A. R, Ley, Timothy J, Parks, William C, Welgus, Howard G

“…We have used the human promonocyte-like U937 cell line as a model to study the regulation of interstitial collagenase and tissue inhibitor of…”
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