Search Results - "Doxtader, Katelyn A."
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Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases
Published in Molecular cell (21-07-2016)“…N6-methyladenosine (m6A) is a prevalent, reversible chemical modification of functional RNAs and is important for central events in biology. The core m6A…”
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2
RNA modifications can affect RNase H1-mediated PS-ASO activity
Published in Molecular therapy. Nucleic acids (14-06-2022)“…Phosphorothioate modified antisense oligonucleotides (PS-ASOs) can reduce gene expression through hybridization to target RNAs and subsequent cleavage by RNase…”
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3
Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor
Published in Molecular cell (20-09-2018)“…S-adenosylmethionine (SAM) is an essential metabolite that acts as a cofactor for most methylation events in the cell. The N6-methyladenosine (m6A)…”
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4
Manipulation by Methylation: Garnishing mRNAs with m6Am
Published in Molecular cell (08-08-2019)“…In two recent publications in Molecular Cell,Boulias et al. (2019) and Sendinc et al. (2019) use complementary approaches to map m6Am modification sites…”
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5
Structural Heterogeneity in Pre-40S Ribosomes
Published in Structure (London) (07-02-2017)“…Late-stage 40S ribosome assembly is a highly regulated dynamic process that occurs in the cytoplasm, alongside the full translation machinery. Seven assembly…”
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6
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases
Published in Molecular cell (30-06-2016)“…N6-methyladenosine (m6A) is a prevalent, reversible chemical modification of functional RNAs and is important for central events in biology. The core m6A…”
Get full text
Journal Article -
7
Manipulation by Methylation: Garnishing mRNAs with m 6 Am
Published in Molecular cell (08-08-2019)“…In two recent publications in Molecular Cell,Boulias et al. (2019) and Sendinc et al. (2019) use complementary approaches to map m Am modification sites…”
Get full text
Journal Article