Search Results - "Doxiadis, Gaby G"

Major histocompatibility complex haplotyping and long-amplicon allele discovery in cynomolgus macaques from Chinese breeding facilities by Karl, Julie A., Graham, Michael E., Wiseman, Roger W., Heimbruch, Katelyn E., Gieger, Samantha M., Doxiadis, Gaby G. M., Bontrop, Ronald E., O’Connor, David H.

“…Very little is currently known about the major histocompatibility complex (MHC) region of cynomolgus macaques ( Macaca fascicularis ; Mafa ) from Chinese…”
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Analysis of macaque BTN3A genes and transcripts in the extended MHC: conserved orthologs of human γδ T cell modulators by de Groot, Nanine, Groen, Rens, Orie, Vaneesha, Bruijnesteijn, Jesse, de Groot, Natasja G., Doxiadis, Gaby G. M., Bontrop, Ronald E.

“…Butyrophilins (BTN), specifically BTN3A, play a central role in the modulation of γδ T cells, which are mainly present in gut and mucosal tissues. BTN3A1 is…”
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mosaic of KIR haplotypes in rhesus macaques by Blokhuis, Jeroen H, van der Wiel, Marit K, Doxiadis, Gaby G. M, Bontrop, Ronald E

“…To further refine and improve biomedical research in rhesus macaques, it is necessary to increase our knowledge concerning both the degree of allelic variation…”
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A Specialist Macaque MHC Class I Molecule with HLA-B27-like Peptide-Binding Characteristics by de Groot, Natasja G, Heijmans, Corrine M C, de Ru, Arnoud H, Janssen, George M C, Drijfhout, Jan W, Otting, Nel, Vangenot, Christelle, Doxiadis, Gaby G M, Koning, Frits, van Veelen, Peter A, Bontrop, Ronald E

“…In different macaque species, the MHC gene is present in abundance, and its gene products are characterized by low cell-surface expression and a highly…”
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The orthologs of HLA-DQ and -DP genes display abundant levels of variability in macaque species by Otting, Nel, van der Wiel, Marit K. H., de Groot, Nanine, de Vos-Rouweler, Annemiek J. M., de Groot, Natasja G., Doxiadis, Gaby G. M., Wiseman, Roger W., O’Connor, David H., Bontrop, Ronald E.

“…The human major histocompatibility complex (MHC) region encodes three types of class II molecules designated HLA-DR, -DQ, and -DP. Both the HLA-DQ and -DP gene…”
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Genomic plasticity of the MHC class I A region in rhesus macaques: extensive haplotype diversity at the population level as revealed by microsatellites by Doxiadis, Gaby G. M, de Groot, Nanine, Otting, Nel, Blokhuis, Jeroen H, Bontrop, Ronald E

“…The Mamu-A genes of the rhesus macaque show different degrees of polymorphism, transcription level variation, and differential haplotype distribution. Per…”
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Haplotype diversity generated by ancient recombination-like events in the MHC of Indian rhesus macaques by Doxiadis, Gaby G. M., de Groot, Nanine, Otting, Nel, de Vos-Rouweler, Annemiek J. M., Bolijn, Maria J., Heijmans, Corrine M. C., de Groot, Natasja G., van der Wiel, Marit K. H., Remarque, Edmond J., Vangenot, Christelle, Nunes, José M., Sanchez-Mazas, Alicia, Bontrop, Ronald E.

“…The Mamu - A , Mamu - B , and Mamu - DRB genes of the rhesus macaque show several levels of complexity such as allelic heterogeneity (polymorphism), copy…”
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Differential recombination dynamics within the MHC of macaque species by de Groot, Nanine, Doxiadis, Gaby G. M., Otting, Nel, de Vos-Rouweler, Annemiek J. M., Bontrop, Ronald E.

“…A panel of 15 carefully selected microsatellites (short tandem repeats, STRs) has allowed us to study segregation and haplotype stability in various macaque…”
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Unparalleled Complexity of the MHC Class I Region in Rhesus Macaques by Otting, Nel, Corrine M. C. Heijmans, Noort, Riet C., de Groot, Natasja G., Gaby G. M. Doxiadis, van Rood, Jon J., Watkins, David I., Bontrop, Ronald E.

“…The highly polymorphic gene products of the classical MHC class I genes in humans (HLA-A, HLA-B, and HLA-C) play a critical role in the immune defense against…”
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MHC class I A region diversity and polymorphism in macaque species by Otting, Nel, de Vos-Rouweler, Annemiek J. M, Heijmans, Corrine M. C, de Groot, Natasja G, Doxiadis, Gaby G. M, Bontrop, Ronald E

“…The HLA-A locus represents a single copy gene that displays abundant allelic polymorphism in the human population, whereas, in contrast, a nonhuman primate…”
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Co-evolution of the MHC class I and KIR gene families in rhesus macaques: ancestry and plasticity by de Groot, Natasja G., Blokhuis, Jeroen H., Otting, Nel, Doxiadis, Gaby G. M., Bontrop, Ronald E.

“…Summary Researchers dealing with the human leukocyte antigen (HLA) class I and killer immunoglobulin receptor (KIR) multi‐gene families in humans are often…”
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Impact of Endogenous Intronic Retroviruses on Major Histocompatibility Complex Class II Diversity and Stability by DOXIADIS, Gaby G. M, DE GROOT, Nanine, BONTROP, Ronald E

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A non-human primate model for gluten sensitivity by Bethune, Michael T, Borda, Juan T, Ribka, Erin, Liu, Michael-Xun, Phillippi-Falkenstein, Kathrine, Jandacek, Ronald J, Doxiadis, Gaby G M, Gray, Gary M, Khosla, Chaitan, Sestak, Karol

“…Gluten sensitivity is widespread among humans. For example, in celiac disease patients, an inflammatory response to dietary gluten leads to enteropathy,…”
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The repertoire of MHC class I genes in the common marmoset: evidence for functional plasticity by van der Wiel, Marit K., Otting, Nel, de Groot, Natasja G., Doxiadis, Gaby G. M., Bontrop, Ronald E.

“…In humans, the classical antigen presentation function of major histocompatibility complex (MHC) class I molecules is controlled by the human leukocyte antigen…”
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AIDS-protective HLA-B27/B57 and chimpanzee MHC class I molecules target analogous conserved areas of HIV-1/SIVcpz by de Groot, Natasja G, Heijmans, Corrine M C, Zoet, Yvonne M, de Ru, Arnoud H, Verreck, Frank A, van Veelen, Peter A, Drijfhout, Jan W, Doxiadis, Gaby G M, Remarque, Edmond J, Doxiadis, Ilias I N, van Rood, Jon J, Koning, Frits, Bontrop, Ronald E

“…In the absence of treatment, most HIV-1-infected humans develop AIDS. However, a minority are long-term nonprogressors, and resistance is associated with the…”
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Evolution of HLA-DRB genes by Doxiadis, Gaby G M, Hoof, Ilka, de Groot, Nanine, Bontrop, Ronald E

“…The HLA region shows diversity concerning the number and content of DRB genes present per haplotype. Similar observations are made for the equivalent regions…”
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Definition of Mafa-A and -B haplotypes in pedigreed cynomolgus macaques (Macaca fascicularis) by Otting, Nel, Doxiadis, Gaby G. M, Bontrop, Ronald E

“…The major histocompatibility complex (MHC) class I B gene/allelic repertoire was investigated in a pedigreed population of cynomolgus macaques of mixed…”
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Male Mating Tactics in Captive Rhesus Macaques (Macaca mulatta): The Influence of Dominance, Markets, and Relationship Quality by Massen, Jorg J. M., Overduin-de Vries, Anne M., de Vos-Rouweler, Annemiek J. M., Spruijt, Berry M., Doxiadis, Gaby G. M., Sterck, Elisabeth H. M.

“…Male mating success in a multimale–multifemale group can depend on several variables: body condition, dominance, coalitions, “friendship,” or an exchange of…”
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snapshot of the Mamu-B genes and their allelic repertoire in rhesus macaques of Chinese origin by Otting, Nel, Heijmans, Corrine M. C, van der Wiel, Marit, de Groot, Natasja G, Doxiadis, Gaby G. M, Bontrop, Ronald E

“…The major histocompatibility complex class I gene repertoire was investigated in a large panel of rhesus macaques of Chinese origin. As observed in Indian…”
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DR haplotype diversity of the cynomolgus macaque as defined by its transcriptome by Doxiadis, Gaby G. M., de Vos-Rouweler, Annemiek J. M., de Groot, Nanine, Otting, Nel, Bontrop, Ronald E.

“…The DR region of particular primate species may display allelic polymorphism and gene copy number variation (region configuration polymorphism). The sum of…”
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