Search Results - "Dowsett, S. A"
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Safety findings from CENTURION, a phase 3 consistency study of lasmiditan for the acute treatment of migraine
Published in Journal of headache and pain (01-12-2021)“…Background Lasmiditan (LTN) is a selective 5-HT 1F receptor agonist for the acute treatment of migraine in adults. We present detailed safety findings from the…”
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Treatment and outcomes for patients with depression who are partial responders to SSRI treatment: Post-hoc analysis findings from the FINDER European observational study
Published in Journal of affective disorders (01-12-2014)“…Abstract Background Remission is the goal in depression, but in practice many patients only experience a partial response to treatment. We sought to determine…”
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Effects of arzoxifene on bone, lipid markers, and safety parameters in postmenopausal women with low bone mass
Published in Osteoporosis international (01-07-2010)“…Summary In this Phase 2 study of postmenopausal women with low bone, arzoxifene (a selective estrogen receptor modulator (SERM)) significantly reduced bone…”
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Neutrophil Response to Dental Plaque by Gender and Race
Published in Journal of dental research (01-08-2009)“…The inflammatory response, which has both genetic and environmental components, is a central mechanism linking oral and systemic diseases. We hypothesized that…”
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Arzoxifene versus raloxifene: effect on bone and safety parameters in postmenopausal women with osteoporosis
Published in Osteoporosis international (01-03-2012)“…Summary Arzoxifene increased bone mineral density and decreased bone turnover to a significantly greater extent than raloxifene. The hot flush incidence was…”
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Helicobacter pylori Infection in Indigenous Families of Central America: Serostatus and Oral and Fingernail Carriage
Published in Journal of Clinical Microbiology (01-08-1999)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Diagnostic Biomarkers of Amyloid and Tau Pathology in Alzheimer’s Disease: An Overview of Tests for Clinical Practice in the United States and Europe
Published in The journal of prevention of Alzheimer's disease (2023)“…Amyloid and tau biomarkers for Alzheimer’s disease are widely recognized diagnostic tools for the identification of Alzheimer’s disease pathology antemortem…”
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‘Time Saved’ As a Demonstration of Clinical Meaningfulness and Illustrated Using the Donanemab TRAILBLAZER-ALZ Study Findings
Published in The journal of prevention of Alzheimer's disease (2023)“…In Alzheimer’s disease (AD) clinical trials, disease-modifying therapies are expected to slow the rate of disease progression. Treatment effects are evaluated…”
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Oral Helicobacter pylori: can we stomach it?
Published in Critical reviews in oral biology and medicine (2003)“…Helicobacter pylori infection is one of the most common in man. The bacterium primarily resides in the human stomach, where it plays a significant role in…”
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Detecting Treatment Group Differences in Alzheimer’s Disease Clinical Trials: A Comparison of Alzheimer’s Disease Assessment Scale - Cognitive Subscale (ADAS-Cog) and the Clinical Dementia Rating - Sum of Boxes (CDR-SB)
Published in The journal of prevention of Alzheimer's disease (2018)“…The Alzheimer’s Disease Assessment Scale’s cognitive subscale (ADAS-Cog) has been widely used as an outcome measure in Alzheimer’s Disease (AD) clinical…”
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The Integrated Alzheimer’s Disease Rating Scale (iADRS) Findings from the EXPEDITION3 Trial
Published in The journal of prevention of Alzheimer's disease (2018)“…The Integrated Alzheimer’s Disease (AD) Rating Scale (iADRS) is a composite tool that combines scores from the AD Assessment Scale-Cognitive subscale…”
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Periodontal disease status of an indigenous population of Guatemala, Central America
Published in Journal of clinical periodontology (01-07-2001)“…Objectives: This study was designed to determine the periodontal disease status of an indigenous Indian community of rural Central America (San Juan La Laguna,…”
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Subgingival microbiota of indigenous Indians of Central America
Published in Journal of clinical periodontology (01-02-2002)“…Objective: To define the subgingival microbial profiles of adult subjects from a previously identified rural community of indigenous Indians in Guatemala,…”
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Comparison of periodontal disease status of adults in two untreated indigenous populations of Guatemala, Central America
Published in Journal of clinical periodontology (01-08-2002)“…Objective: To compare the periodontal disease levels of two distinct indigenous populations of Guatemala, Central America, to determine whether differences…”
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Extending scientific horizons in the developing world - the Central American experience
Published in British dental journal (28-09-2002)“…The juxtaposition of 'oral disease' and 'developing countries' invariably evokes thoughts of how one might assist these nations in attaining 'a healthy mouth…”
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The impact of stress urinary incontinence on sexual activity in women
Published in Cleveland Clinic journal of medicine (01-03-2005)“…In women, stress urinary incontinence is a common problem that may lead to sexual dysfunction. We review the epidemiological data, the pathophysiology, and the…”
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Functional integrity of human neutrophils following 24 hour incubation with hydroxyapatite and fluoride
Published in Journal of bioluminescence and chemiluminescence (01-07-1997)“…We have previously shown that hydroxyapatite (HA) priming of human neutrophils to a second stimulus of formyl‐methionyl‐leucyl‐phenylalanine (fMPL) is…”
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Systemic Neutrophil Response Resulting From Dental Plaque Accumulation
Published in Journal of periodontology (1970) (01-02-2001)“…Background: There is considerable current interest in putative relationships between oral and systemic diseases. Since the host response to oral bacteria may…”
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Effect of Raloxifene on Cardiovascular Adverse Events in Postmenopausal Women With Osteoporosis
Published in The American journal of cardiology (15-02-2006)“…The impact of selective estrogen receptor modulators on cardiovascular disease outcomes in postmenopausal women remains unclear. This analysis assessed the…”
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Cardiovascular effects of raloxifene: the arterial and venous systems
Published in The American heart journal (01-05-2004)“…Cardiovascular disease caused by atherosclerosis is the largest single killer of women. Prior observational data had suggested that hormone therapy may have…”
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