Search Results - "Dowsett, S A"

Safety findings from CENTURION, a phase 3 consistency study of lasmiditan for the acute treatment of migraine by Tassorelli, C, Bragg, S, Krege, JH, Doty, EG, Ardayfio, PA, Ruff, D, Dowsett, SA, Schwedt, T

“…Background Lasmiditan (LTN) is a selective 5-HT 1F receptor agonist for the acute treatment of migraine in adults. We present detailed safety findings from the…”
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Treatment and outcomes for patients with depression who are partial responders to SSRI treatment: Post-hoc analysis findings from the FINDER European observational study by Lenox-Smith, A, Martinez, J.M, Perahia, D, Dowsett, S.A, Dennehy, E.B, Lopez-Romero, P, Demyttenaere, K

“…Abstract Background Remission is the goal in depression, but in practice many patients only experience a partial response to treatment. We sought to determine…”
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Effects of arzoxifene on bone, lipid markers, and safety parameters in postmenopausal women with low bone mass by Downs, R. W. Jr, Moffett, A. M, Ghosh, A, Cox, D. A, Dowsett, S. A, Harper, K

“…Summary In this Phase 2 study of postmenopausal women with low bone, arzoxifene (a selective estrogen receptor modulator (SERM)) significantly reduced bone…”
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Neutrophil Response to Dental Plaque by Gender and Race by Wahaidi, V.Y., Dowsett, S.A., Eckert, G.J., Kowolik, M.J.

“…The inflammatory response, which has both genetic and environmental components, is a central mechanism linking oral and systemic diseases. We hypothesized that…”
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Arzoxifene versus raloxifene: effect on bone and safety parameters in postmenopausal women with osteoporosis by Kendler, D. L., Palacios, S., Cox, D. A., Stock, J., Alam, J., Dowsett, S. A., Zanchetta, J.

“…Summary Arzoxifene increased bone mineral density and decreased bone turnover to a significantly greater extent than raloxifene. The hot flush incidence was…”
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Helicobacter pylori Infection in Indigenous Families of Central America: Serostatus and Oral and Fingernail Carriage by DOWSETT, S. A, ARCHILA, L, SEGRETO, V. A, GONZALEZ, C. R, SILVA, A, VASTOLA, K. A, BARTIZEK, R. D, KOWOLIK, M. J

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Diagnostic Biomarkers of Amyloid and Tau Pathology in Alzheimer’s Disease: An Overview of Tests for Clinical Practice in the United States and Europe by Iaccarino, Leonardo, Burnham, S. C., Dell’Agnello, G., Dowsett, S. A., Epelbaum, S.

“…Amyloid and tau biomarkers for Alzheimer’s disease are widely recognized diagnostic tools for the identification of Alzheimer’s disease pathology antemortem…”
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‘Time Saved’ As a Demonstration of Clinical Meaningfulness and Illustrated Using the Donanemab TRAILBLAZER-ALZ Study Findings by Dickson, S. P., Wessels, Alette M., Dowsett, S. A., Mallinckrodt, C., Sparks, J. D., Chatterjee, S., Hendrix, S.

“…In Alzheimer’s disease (AD) clinical trials, disease-modifying therapies are expected to slow the rate of disease progression. Treatment effects are evaluated…”
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Oral Helicobacter pylori: can we stomach it? by Dowsett, S A, Kowolik, M J

“…Helicobacter pylori infection is one of the most common in man. The bacterium primarily resides in the human stomach, where it plays a significant role in…”
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Detecting Treatment Group Differences in Alzheimer’s Disease Clinical Trials: A Comparison of Alzheimer’s Disease Assessment Scale - Cognitive Subscale (ADAS-Cog) and the Clinical Dementia Rating - Sum of Boxes (CDR-SB) by Wessels, Alette M., Dowsett, S. A., Sims, J. R.

“…The Alzheimer’s Disease Assessment Scale’s cognitive subscale (ADAS-Cog) has been widely used as an outcome measure in Alzheimer’s Disease (AD) clinical…”
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The Integrated Alzheimer’s Disease Rating Scale (iADRS) Findings from the EXPEDITION3 Trial by Wessels, Alette M., Andersen, S. W., Dowsett, S. A., Siemers, E. R.

“…The Integrated Alzheimer’s Disease (AD) Rating Scale (iADRS) is a composite tool that combines scores from the AD Assessment Scale-Cognitive subscale…”
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Periodontal disease status of an indigenous population of Guatemala, Central America by Dowsett, S. A., Archila, L., Segreto, V. A., Eckert, G. J., Kowolik, M. J.

“…Objectives: This study was designed to determine the periodontal disease status of an indigenous Indian community of rural Central America (San Juan La Laguna,…”
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Subgingival microbiota of indigenous Indians of Central America by Dowsett, S. A., Kowolik, M. J., Archila, L. A., Eckert, G. J., LeBlanc, D. J.

“…Objective: To define the subgingival microbial profiles of adult subjects from a previously identified rural community of indigenous Indians in Guatemala,…”
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Comparison of periodontal disease status of adults in two untreated indigenous populations of Guatemala, Central America by Dowsett, S. A., Eckert, G. J., Kowolik, M. J.

“…Objective:  To compare the periodontal disease levels of two distinct indigenous populations of Guatemala, Central America, to determine whether differences…”
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Extending scientific horizons in the developing world - the Central American experience by Dowsett, S A, Kowolik, M J

“…The juxtaposition of 'oral disease' and 'developing countries' invariably evokes thoughts of how one might assist these nations in attaining 'a healthy mouth…”
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The impact of stress urinary incontinence on sexual activity in women by Barber, Matthew D, Dowsett, Sherie A, Mullen, Karen J, Viktrup, Lars

“…In women, stress urinary incontinence is a common problem that may lead to sexual dysfunction. We review the epidemiological data, the pathophysiology, and the…”
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Functional integrity of human neutrophils following 24 hour incubation with hydroxyapatite and fluoride by Dowsett, S. A., Hyvönen, P. M., Kowolik, M. J.

“…We have previously shown that hydroxyapatite (HA) priming of human neutrophils to a second stimulus of formyl‐methionyl‐leucyl‐phenylalanine (fMPL) is…”
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Systemic Neutrophil Response Resulting From Dental Plaque Accumulation by Kowolik, Michael J., Dowsett, Sherie A., Rodriguez, Jessica, De La Rosa R, Manuel, Eckert, George J.

“…Background: There is considerable current interest in putative relationships between oral and systemic diseases. Since the host response to oral bacteria may…”
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Effect of Raloxifene on Cardiovascular Adverse Events in Postmenopausal Women With Osteoporosis by Ensrud, Kristine, Riccardo Genazzani, Andrea, Geiger, Mary Jane, McNabb, Michelle, Dowsett, Sherie A., Cox, David A., Barrett-Connor, Elizabeth

“…The impact of selective estrogen receptor modulators on cardiovascular disease outcomes in postmenopausal women remains unclear. This analysis assessed the…”
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Cardiovascular effects of raloxifene: the arterial and venous systems by Blumenthal, Roger S, Baranowski, Bryan, Dowsett, Sherie A

“…Cardiovascular disease caused by atherosclerosis is the largest single killer of women. Prior observational data had suggested that hormone therapy may have…”
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