Search Results - "Downs, David A"

Synthesis and potential antipsychotic activity of 1H-imidazo[1,2-c]pyrazolo[3,4-e]pyrimidines by DeWald, Horace A, Beeson, Nicholas W, Hershenson, Fred M, Wise, Lawrence D, Downs, David A, Heffner, Thomas G, Coughenour, Linda L, Pugsley, Thomas A

“…The synthesis of a series of 1H-imidazo[1,2-c]pyrazolo[3,4-e]pyrimidines is reported along with the effects of these compounds in preclinical tests for…”
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(5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)(2-fluorophenyl)methanones. A series of novel potential antipsychotic agents by Wise, Lawrence D, Butler, Donald E, DeWald, Horace A, Lustgarten, David, Coughenour, Linda L, Downs, David A, Heffner, Thomas G, Pugsley, Thomas A

“…(5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)(2-fluorophenyl)methanone (1) was found to have an antipsychotic-like profile in behavioral tests predictive of…”
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N6-(2,2-diphenylethyl)adenosine, a novel adenosine receptor agonist with antipsychotic-like activity by Bridges, Alexander J, Moos, Walter H, Szotek, Deedee L, Trivedi, Bharat K, Bristol, James A, Heffner, Thomas G, Bruns, Robert F, Downs, David A

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Examination of a series of 8-[3-[bis(4-fluorophenyl)amino]propyl]-1-aryl-1,3,8-triazaspiro[4.5]decan-4-ones as potential antipsychotic agents by Wise, Lawrence D, Pattison, Ian C, Butler, Donald E, DeWald, Horace A, Lewis, Edward P, Lobbestael, Sandra J, Tecle, Haile, Coughenour, Linda L, Downs, David A, Poschel, B. P. H

“…8-[3-[Bis(4-fluorophenyl)amino]propyl]-1-phenyl-1,3,8- triazaspiro[4.5]decan-4-one (3) and related compounds have been shown to have antipsychotic profiles in…”
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1,3-Dialkyl-4-(iminoarylmethyl)-1H-pyrazol-5-ols. A series of novel potential antipsychotic agents by Wise, Lawrence D, Butler, Donald E, DeWald, Horace A, Lustgarten, David M, Pattison, Ian C, Schweiss, Dieter N, Coughenour, Linda L, Downs, David A, Heffner, Thomas G, Pugsley, Thomas A

“…2-(Diethylamino)-N-[4-(2-fluorobenzoyl)-1,3-dimethyl-1H-pyrazol-5-yl] acetamide (1) was recently found to have an antipsychotic-like profile in behavioral…”
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FIXED-RATIO ESCAPE AND AVOIDANCE-ESCAPE FROM NALOXONE IN MORPHINE-DEPENDENT MONKEYS: EFFECTS OF NALOXONE DOSE AND MORPHINE PRETREATMENT by Downs, David A., Woods, James H.

“…Lever pressing by rhesus monkeys was maintained by morphine injections during four equally spaced sessions each day. During other periods, lever pressing was…”
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Comparison of the behavioral effects of adenosine agonists and dopamine antagonists in mice by HEFFNER, T. G, WILEY, J. N, WILLIAMS, A. E, BRUNS, R. F, COUGHENOUR, L. L, DOWNS, D. A

“…The adenosine agonists 5'-N-ethylcarboxamideadenosine (NECA), 2-chloroadenosine (2-CLA), N6-cyclohexyladenosine (CHA), N6-cyclopentyladenosine (CPA),…”
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PUNISHMENT OF ELICITED EYEBLINKS IN RABBITS by DOWNS, DAVID A

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Food- and drug-reinforced responding: Effects of DITA and d-amphetamine by Downs, David A., Woods, James H.

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Interactions of acetylmethadol or methadone with other drugs in rhesus monkeys by Downs, D A

“…Behavioral effects and blood or plasma levels of d-amphetamine, ethanol, cocaine, and diazepam were examined in rhesus monkeys treated chronically with…”
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Naloxone-precipitated jumping in mice pretreated with acute injections of opioids by Wiley, J N, Downs, D A

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Lack of antagonism by naloxone of the analgesic and locomotor stimulant actions of ketamine by Wiley, J N, Downs, D A

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FIXED‐RATIO ESCAPE AND AVOIDANCE‐ESCAPE FROM NALOXONE IN MORPHINE‐DEPENDENT MONKEYS: EFFECTS OF NALOXONE DOSE AND MORPHINE PRETREATMENT 1 by Downs, David A., Woods, James H.

“…Lever pressing by rhesus monkeys was maintained by morphine injections during four equally spaced sessions each day. During other periods, lever pressing was…”
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FIXED‐RATIO ESCAPE AND AVOIDANCE‐ESCAPE FROM NALOXONE IN MORPHINE‐DEPENDENT MONKEYS: EFFECTS OF NALOXONE DOSE AND MORPHINE PRETREATMENT1 by Downs, David A., Woods, James H.

“…Lever pressing by rhesus monkeys was maintained by morphine injections during four equally spaced sessions each day. During other periods, lever pressing was…”
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Self-administration of heroin, acetylmethadol, morphine, and methadone in rhesus monkeys by Harrigan, S E, Downs, D A

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Cocaine, d-amphetamine, and pentobarbital effects on responding maintained by food or cocaine in rhesus monkeys by Herling, S, Downs, D A, Woods, J H

“…The effects of IM injections of cocaine, d-amphetamine, and pentobarbital were studied in rhesus monkeys whose lever-press responding was maintained under a…”
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Codeine- and cocaine-reinforced responding in rhesus monkeys: effects of dose on response rates under a fixed-ratio schedule by Downs, D A, Woods, J H

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Time-action and behavioral effects of amphetamine, ethanol, and acetylmethadol by Downs, D A, Braude, M C

“…As time increased between drug administration and the start of experimental sessions, effects of drugs on food-maintained responding in rhesus monkeys…”
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Catecholamine content of chromaffin granule "ghosts' isolated from bovine adrenal glands by Deupree, J D, Weaver, J A, Downs, D A

“…Studies on the mechanism of catecholamine transport into chromaffin granules is complicated by the release of endogenous catecholamines. To overcome this…”
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Oral vs parenteral drug effects on schedule-controlled behavior in rhesus monkeys by Downs, D A, Miller, L E, Wiley, J N, Johnston, D E

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