Search Results - "Downing, Scott S"

Prodromal dysfunction of α5GABA-A receptor modulated hippocampal ripples occurs prior to neurodegeneration in the TgF344-AD rat model of Alzheimer's disease by Ratner, Marcia H., Downing, Scott S., Guo, Ouyang, Odamah, KathrynAnn E., Stewart, Tara M., Kumaresan, Vidhya, Robitsek, R. Jonathan, Xia, Weiming, Farb, David H.

“…Decades of research attempting to slow the onset of Alzheimer's disease (AD) indicates that a better understanding of memory will be key to the discovery of…”
Get full text

Benzodiazepine modulation of partial agonist efficacy and spontaneously active GABA(A) receptors supports an allosteric model of modulation by Downing, Scott S, Lee, Yan T, Farb, David H, Gibbs, Terrell T

“…Benzodiazepines (BZDs) have been used extensively for more than 40 years because of their high therapeutic index and low toxicity. Although BZDs are understood…”
Get full text

Benzodiazepine modulation of partial agonist efficacy and spontaneously active GABAA receptors supports an allosteric model of modulation by Downing, Scott S, Lee, Yan T, Farb, David H, Gibbs, Terrell T

“…1 Benzodiazepines (BZDs) have been used extensively for more than 40 years because of their high therapeutic index and low toxicity. Although BZDs are…”
Get full text

An allosteric gating model for the benzodiazepine modulation of the GABA-A receptor by Downing, Scott S

“…Benzodiazepines (BZDs) have found extensive use in the clinic for more than 40 years because of their high therapeutic index and low toxicity. Whereas BZDs…”
Get full text