Search Results - "Downey, Francis X"

Pulmonary Artery Angiomatoid Fibrous Histiocytoma Mimicking a Large Pulmonary Embolism by Haug, Logan P., Zarka, Matthew A., D’Cunha, Jonathan, Downey, Francis X., Seetharam, Mahesh, Yang, Ming

“…A 39-year-old man presented with progressive dyspnea and lower extremity edema. Doppler ultrasound demonstrated bilateral leg partially occluded venous…”
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Enhanced store-operated Ca2+ influx and ORAI1 expression in ventricular fibroblasts from human failing heart by Ross, Gracious R., Bajwa, Tanvir, Edwards, Stacie, Emelyanova, Larisa, Rizvi, Farhan, Holmuhamedov, Ekhson L., Werner, Paul, Downey, Francis X., Tajik, A. Jamil, Jahangir, Arshad

“…Excessive cardiac fibrosis, characterized by increased collagen-rich extracellular matrix (ECM) deposition, is a major predisposing factor for mechanical and…”
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Practical value of identifying antibodies to cryptic HLA epitopes in cardiac transplantation by Oaks, Martin, PhD, Michel, Karen, BS, Sulemanjee, Nasir Z., MD, Thohan, Vinay, MD, Downey, Francis X., MD

“…Background Identification of antibodies to human leukocyte antigens (HLA) by single antigen bead arrays has led to the common practice of virtual…”
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Impact of statins on cellular respiration and de‐differentiation of myofibroblasts in human failing hearts by Emelyanova, Larisa, Sra, Amar, Schmuck, Eric G., Raval, Amish N., Downey, Francis X., Jahangir, Arshad, Rizvi, Farhan, Ross, Gracious R.

“…Aims Fibroblast to myofibroblast trans‐differentiation with altered bioenergetics precedes cardiac fibrosis (CF). Either prevention of differentiation or…”
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Cardiac Sarcoid: A Chameleon Masquerading as Hypertrophic Cardiomyopathy and Dilated Cardiomyopathy in the Same Patient by Agarwal, Anushree, Sulemanjee, Nasir Z., Cheema, Omar, Downey, Francis X., Tajik, A. Jamil

“…Sarcoidosis is a multisystem, granulomatous disease of unknown etiology often seen in young adults, with cardiac involvement in more than one‐quarter of…”
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Positive Heparin-Platelet Factor 4 Antibody Complex and Cardiac Surgical Outcomes by Kress, David C., MD, Aronson, Solomon, MD, McDonald, Monica L., MD, Malik, Mohammad I., MD, Divgi, Ajit B., MD, Tector, Alfred J., MD, Downey, Francis X., MD, Anderson, Alfred J., MS, Stone, Mia, MS, RN, Clancy, Cassandra, RN

“…Background Given the large number of patients undergoing cardiac operations annually, it is important to identify populations at high risk for adverse…”
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Practical Considerations for and Outcomes of Interfacility ECMO Transfer of Patients With COVID-19 During a Pandemic: Mayo Clinic Experience by Sen, Ayan, Blakeman, Stephanie, DeValeria, Patrick A., Peworski, Dominique, Lanza, Louis A., Downey, Francis X., Alwardt, Cory M., Dobberpuhl, Jeffrey G., DeMarco, Matthew, Callisen, Hannelisa, Shively, Jennifer, McKay, Kelly, Singbartl, Kai, Sell-Dottin, Kristen A., D’Cunha, Jonathan, Patel, Bhavesh M.

“…Interfacility transport of a critically ill patient with acute respiratory distress syndrome (ARDS) may be necessary for a higher level of care or initiation…”
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Comprehensive Analysis of Stroke in the Long-Term Cohort of the MOMENTUM 3 Study: A Randomized Controlled Trial of the HeartMate 3 Versus the HeartMate II Cardiac Pump by Colombo, Paolo C, Mehra, Mandeep R, Goldstein, Daniel J, Estep, Jerry D, Salerno, Christopher, Jorde, Ulrich P, Cowger, Jennifer A, Cleveland, Joseph C, Uriel, Nir, Sayer, Gabriel, Skipper, Eric R, Downey, Francis X, Ono, Masahiro, Hooker, Robert, Anyanwu, Anelechi C, Givertz, Michael M, Mahr, Claudius, Topuria, Ia, Somo, Sami I, Crandall, Daniel L, Horstmanshof, Douglas A

“…BACKGROUND:The MOMENTUM 3 study (Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy With HeartMate 3) has…”
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Xenoreactive antibodies and latent fibrin formation in VAD and cardiac transplant recipients can confound the detection and measurement of anti‐AT1R antibodies by Oaks, Martin, Michel, Karen, Downey, Francis X., Thohan, Vinay

“…Autoantibodies to the angiotensin II type 1 receptor (AT1R) are thought to be important in antibody‐mediated rejection (AMR), especially in the absence of…”
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Quo Vadis, ECMO? Multidisciplinary Hybrid Extra Corporeal Membrane Oxygenation Rounds During the COVID-19 Pandemic by Blakeman, Stephanie, Danley, Shiloh, Amity, Marjorie, DeValeria, Patrick, Miller, Brittany, Alwardt, Cory, Kiley, Brigid, Meltzer, Ellen C., Patel, Bhavesh, Humphrey, Eric, Yee, Claire, Downey, Francis X., D'Cunha, Jonathan, Sen, Ayan

“…The complex care of patients on extracorporeal membrane oxygenation (ECMO) requires a high level of collaboration between multiple medical specialties and…”
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Deletion of transcription factor AP‐2α gene attenuates fibroblast differentiation into myofibroblast by Ross, Gracious R., Edwards, Stacie, Warner, Catherine, Homar, Peter, Downey, Francis X., Emelyanova, Larisa, Rizvi, Farhan, Jahangir, Arshad

“…[...]activated myofibroblasts accumulate within pathological lesions of various fibrotic disorders, including patchy and interstitial fibrosis in progressive…”
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Purely internal thoracic artery grafts: outcomes by Tector, Alfred J, McDonald, Monica L, Kress, David C, Downey, Francis X, Schmahl, Terence M

“…Background. Most of our patients with coronary artery disease have undergone bypass exclusively with purely internal thoracic artery grafts (PITA). Our goal…”
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Deep Sternal Wound Infection Caused by Rhizopus Species After Coronary Artery Bypass Graft by Cunningham, Cody A, Grys, Thomas E, Downey, Francis X, Saling, Christopher F, Orenstein, Robert, Blair, Janis E

“…Deep sternal wound infection is a rare complication of cardiac surgery that is typically caused by skin resident flora, such as species of and . Infections…”
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Surgical Removal of a Migrated WATCHMAN Device by Saleeb, Andrew G, Farina, Juan M, Jenkins, Asher, Zeineddine, Rawan, Shawwaf, Kenan, Yang, Eric H, Alsidawi, Said, Jaroszewski, Dawn E, Downey, Francis X

“…The WATCHMAN™ atrial appendage closure device is designed to reduce the risk of stroke in patients with nonvalvular atrial fibrillation who are not suitable…”
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Orthotopic Heart Transplantation in a Patient With Corrected L-transposition of Great Arteries and Dextrocardia by Tector, Alfred J., MD, Savitt, Michael, MD, Dankle, C. Jennifer, DO, Downey, Francis X., MD, Levin, Jonathan, MD, Nelson, Rory, MD, Gupta, Anjan, MD, Kay, Jonathan, MD

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Abstract 15690: Fibroblasts From Failing Human Heart Exhibit Increased Sensitivity to Dronedarone-Induced Oxidative Stress and Cell Death by Emelyanova, Larisa, Liu, Mingyuan, Yang, Guangyuan, Stoeckl, Elizabeth, Holmuhamedov, Ekhson, Rizvi, Farhan, Ross, Gracious, Downey, Francis X, Tajik, A Jamil, Jahangir, Arshad

“…IntroductionDronedarone (DR), a structural analog of amiodarone designed to reduce its extracardiac toxicity, recently was shown in clinical trials to increase…”
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Comprehensive Analysis of Stroke in the Long-Term Cohort of the MOMENTUM 3 Study by Colombo, Paolo C, Mehra, Mandeep R, Goldstein, Daniel J, Estep, Jerry D, Salerno, Christopher, Jorde, Ulrich P, Cowger, Jennifer A, Cleveland, Jr, Joseph C, Uriel, Nir, Sayer, Gabriel, Skipper, Eric R, Downey, Francis X, Ono, Masahiro, Hooker, Jr, Robert, Anyanwu, Anelechi C, Givertz, Michael M, Mahr, Claudius, Topuria, Ia, Somo, Sami I, Crandall, Daniel L, Horstmanshof, Douglas A

“…The MOMENTUM 3 study (Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy With HeartMate 3) has demonstrated…”
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The effect of pre-transplant and post-transplant anti-AT1R antibodies in heart transplant recipients by Thohan, Vinay, Michel, Karen, Purohit, Anil, Malick, Owais, Downey, Francis X., Oaks, Martin

“…•The presence of anti-AT1R antibodies in cardiac transplants either pre- or post-transplant was not associated with increased rejection, mortality, or cardiac…”
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Pharmacological strategies for prevention of postoperative atrial fibrillation by Turagam, Mohit K, Downey, Francis X, Kress, David C, Sra, Jasbir, Tajik, A Jamil, Jahangir, Arshad

“…Atrial fibrillation (AF) complicating cardiac surgery continues to be a major problem that increases the postoperative risk of stroke, myocardial infarction,…”
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A review of leukofiltration in cardiac surgery: the time course of reperfusion injury may facilitate study design of anti-inflammatory effects by Ortolano, Girolamo A, Aldea, Gabriel S, Lilly, Kevin, O’Gara, Paul, Alkon, Joseph D, Madera, Frederick, Murad, Tarek, Altenbern, Charles P, Tritt, Charles S, Capetandes, Anthony, Gikakis, Nicolas S, Wenz, Barry, Shemin, Richard J, Downey, Francis X

“…The systemic inflammatory response syndrome (SIRS) is a well-recognized phenomenon attending cardiopulmo-nary bypass (CPB) surgery. SIRS leads to costly…”
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