Search Results - "Downes, Michael R."

A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease by Caussy, Cyrielle, Tripathi, Anupriya, Humphrey, Greg, Bassirian, Shirin, Singh, Seema, Faulkner, Claire, Bettencourt, Ricki, Rizo, Emily, Richards, Lisa, Xu, Zhenjiang Z., Downes, Michael R., Evans, Ronald M., Brenner, David A., Sirlin, Claude B., Knight, Rob, Loomba, Rohit

“…The presence of cirrhosis in nonalcoholic-fatty-liver-disease (NAFLD) is the most important predictor of liver-related mortality. Limited data exist concerning…”
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Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet by Krebs, Philippe, Fan, Weiwei, Chen, Yen-Hui, Tobita, Kimimasa, Downes, Michael R, Wood, Malcolm R, Sun, Lei, Li, Xiaohong, Xia, Yu, Ding, Ning, Spaeth, Jason M, Moresco, Eva Marie Y, Boyer, Thomas G, Lo, Cecilia Wen Ya, Yen, Jeffrey, Evans, Ronald M, Beutler, Bruce

“…Deficiencies of subunits of the transcriptional regulatory complex Mediator generally result in embryonic lethality, precluding study of its physiological…”
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Extrahepatic Cancer Suppresses Nuclear Receptor―Regulated Drug Metabolism by KACEVSKA, Marina, DOWNES, Michael R, SHARMA, Rohini, EVANS, Ronald M, CLARKE, Stephen J, LIDDLE, Christopher, ROBERTSON, Graham R

“…To determine the mechanisms by which tumors situated in extrahepatic sites can cause profound changes in hepatic drug clearance, contributing to altered drug…”
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EXTRA-HEPATIC CANCER SUPPRESSES NUCLEAR RECEPTOR REGULATED DRUG METABOLISM by Kacevska, Marina, Downes, Michael R., Sharma, Rohini, Evans, Ronald M., Clarke, Stephen J., Liddle, Christopher, Robertson, Graham R.

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