Search Results - "Downes, Michael A"
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Case series profile of olanzapine post‐injection delirium/sedation syndrome
Published in British journal of clinical pharmacology (01-02-2023)“…Olanzapine pamoate is an intramuscular depot injection for the treatment of schizophrenia. Approximately 1.4% of patients develop a serious adverse event…”
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The Safety and Effectiveness of Droperidol for Sedation of Acute Behavioral Disturbance in the Emergency Department
Published in Annals of emergency medicine (01-09-2015)“…Study objective We investigate the safety and effectiveness of droperidol for sedation of acute behavioral disturbance in the emergency department (ED)…”
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3
Ketamine as Rescue Treatment for Difficult-to-Sedate Severe Acute Behavioral Disturbance in the Emergency Department
Published in Annals of emergency medicine (01-05-2016)“…Study objective We investigate the effectiveness and safety of ketamine to sedate patients with severe acute behavioral disturbance who have failed previous…”
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Randomized Controlled Trial of Intramuscular Droperidol Versus Midazolam for Violence and Acute Behavioral Disturbance: The DORM Study
Published in Annals of emergency medicine (01-10-2010)“…Study objective We determine whether droperidol, midazolam, or the combination is more effective for intramuscular sedation in violent and acute behavioral…”
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Impact of an emergency short stay unit on emergency department performance of poisoned patients
Published in The American journal of emergency medicine (01-05-2017)“…Abstract Objectives This was a before and after study which sought to assess the impact of opening an ED short stay unit (ESSU) on the ED performance of…”
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6
Lack of cholinergic features in healthcare workers caring for a patient with organophosphate poisoning
Published in Clinical toxicology (Philadelphia, Pa.) (03-08-2023)“…INTRODUCTIONControversy exists with regard to risk of secondary exposure of health care workers caring for patients who have ingested an organophosphate…”
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Reality of clonidine poisoning in children and adolescents
Published in Journal of paediatrics and child health (01-06-2023)“…Aim We aimed to describe the severity of clonidine poisonings in a paediatric population referred to a tertiary toxicology service. Methods We undertook a…”
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Calcium channel blocker overdose: Not all the same toxicity
Published in British journal of clinical pharmacology (21-09-2024)“…Calcium channel blocker (CCB) overdose remains an important poisoning, with increasing availability of dihydropyridines. We aimed to compare the severity and…”
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Growing burden of gamma‐hydroxybutyrate intoxication on emergency department resource utilisation
Published in Emergency medicine Australasia (01-10-2024)“…Objective Recreational gamma‐hydroxybutyrate (GHB) use is rising in Australia. We aimed to describe ED presentation patterns related to GHB over time and the…”
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A randomized controlled trial and prospective cohort investigating antivenom for red-bellied black snake envenomation
Published in Clinical toxicology (Philadelphia, Pa.) (01-06-2024)“…Antivenom is first line treatment for snake envenomation worldwide, despite few placebo controlled clinical trials demonstrating effectiveness. We aimed to…”
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Paediatric poisoning presentations reported to a regional toxicology service in Australia
Published in Journal of paediatrics and child health (01-07-2021)“…Aim The aim of this study is to describe the epidemiology and health‐care utilisation of paediatric emergency department (ED) presentations due to poisoning…”
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12
Low‐dose ketamine provides poor analgesia for pain in redback spider envenoming
Published in British journal of clinical pharmacology (01-10-2019)“…Redback spider envenoming causes severe pain lasting several days. A recent clinical trial found that antivenom is not effective. We investigated ketamine for…”
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13
The impact of a standardised intramuscular sedation protocol for acute behavioural disturbance in the emergency department
Published in BMC emergency medicine (28-06-2010)“…Acute behavioural disturbance (ABD) is an increasing problem in emergency departments. This study aimed to determine the impact of a structured intramuscular…”
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Re: Redback spider bites in children in South Australia: A 10‐year review of antivenom effectiveness
Published in Emergency medicine Australasia (01-04-2022)Get full text
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Factors associated with paediatric and adolescent Emergency Department presentations involving acute behavioural disturbance events
Published in Journal of paediatrics and child health (01-01-2022)“…Aim Studies reporting factors associated with paediatric/adolescent acute behavioural disturbance (ABD) in the Emergency Department (ED) are lacking. The aim…”
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Use of a tablet-based application for clinical handover and data collection
Published in Clinical toxicology (Philadelphia, Pa.) (02-07-2020)“…Context: Inpatient toxicology services undertake remote as well as inpatient management of poisoned patients. The aim of this study is to describe the…”
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A prospective observational study of a novel 2-phase infusion protocol for the administration of acetylcysteine in paracetamol poisoning
Published in Clinical toxicology (Philadelphia, Pa.) (07-02-2016)“…Context: The current 3-phase acetylcysteine infusion for paracetamol poisoning delivers half the dose over 15-60 min and frequently results in adverse…”
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Clinical features of serum sickness after Australian snake antivenom
Published in Toxicon (Oxford) (15-12-2015)“…Serum sickness is a delayed immune reaction in which the immune system responds to a protein in antiserum as a potentially harmful substance and mounts an…”
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Acute behavioural disturbance associated with phenibut purchased via an internet supplier
Published in Clinical toxicology (Philadelphia, Pa.) (09-08-2015)“…Context. Toxicity from recreational substances marketed for other purposes is a well-documented clinical entity. We present two cases of phenibut toxicity…”
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Difficult to sedate case of acute behavioural disturbance secondary to baclofen withdrawal
Published in Emergency medicine Australasia (01-06-2019)Get full text
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