Search Results - "Dowling, Damian K."

Reactive oxygen species as universal constraints in life-history evolution by Dowling, Damian K., Simmons, Leigh W.

“…Evolutionary theory is firmly grounded on the existence of trade-offs between life-history traits, and recent interest has centred on the physiological…”
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Small mitochondrial RNAs as mediators of nuclear gene regulation, and potential implications for human health by Pozzi, Andrea, Dowling, Damian K.

“…Much research has focused on the effects of pathogenic mitochondrial mutations on health. Notwithstanding, the mechanisms regulating the link between these…”
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Mitochondria, Maternal Inheritance, and Male Aging by Camus, M. Florencia, Clancy, David J., Dowling, Damian K.

“…The maternal transmission of mitochondrial genomes invokes a sex-specific selective sieve, whereby mutations in mitochondrial DNA can only respond to selection…”
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Mitochondrial Replacement, Evolution, and the Clinic by Reinhardt, Klaus, Dowling, Damian K., Morrow, Edward H.

“…Mitochondrial replacement therapy might bear health risks, especially for males. Mitochondrial diseases [often caused by mutations in mitochondrial DNA…”
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Assessing the fitness consequences of mitonuclear interactions in natural populations by Hill, Geoffrey E., Havird, Justin C., Sloan, Daniel B., Burton, Ronald S., Greening, Chris, Dowling, Damian K.

“…ABSTRACT Metazoans exist only with a continuous and rich supply of chemical energy from oxidative phosphorylation in mitochondria. The oxidative…”
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Single Nucleotides in the mtDNA Sequence Modify Mitochondrial Molecular Function and Are Associated with Sex-Specific Effects on Fertility and Aging by Camus, M. Florencia, Wolf, Jochen B.W., Morrow, Edward H., Dowling, Damian K.

“…Mitochondria underpin energy conversion in eukaryotes. Their small genomes have been the subject of increasing attention, and there is evidence that…”
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Experimental evidence that thermal selection shapes mitochondrial genome evolution by Lajbner, Zdeněk, Pnini, Reuven, Camus, M. Florencia, Miller, Jonathan, Dowling, Damian K.

“…Mitochondria are essential organelles, found within eukaryotic cells, which contain their own DNA. Mitochondrial DNA (mtDNA) has traditionally been used in…”
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Mitonuclear interactions shape both direct and parental effects of diet on fitness and involve a SNP in mitoribosomal 16s rRNA by Dobson, Adam J, Voigt, Susanne, Kumpitsch, Luisa, Langer, Lucas, Voigt, Emmely, Ibrahim, Rita, Dowling, Damian K, Reinhardt, Klaus

“…Nutrition is a primary determinant of health, but responses to nutrition vary with genotype. Epistasis between mitochondrial and nuclear genomes may cause some…”
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Aging: Manipulating Sex Differences by Dowling, Damian K.

“…A new study reports that male, but not female, longevity evolves in response to increasing male mortality. The sex gap in longevity widens depending on the…”
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GENETIC ARCHITECTURE OF METABOLIC RATE: ENVIRONMENT SPECIFIC EPISTASIS BETWEEN MITOCHONDRIAL AND NUCLEAR GENES IN AN INSECT by Arnqvist, Göran, Dowling, Damian K., Eady, Paul, Gay, Laurene, Tregenza, Tom, Tuda, Midori, Hosken, David J.

“…The extent to which mitochondrial DNA (mtDNA) variation is involved in adaptive evolutionary change is currently being reevaluated. In particular, emerging…”
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Fragmentation in mitochondrial genomes in relation to elevated sequence divergence and extreme rearrangements by Feng, Shiqian, Pozzi, Andrea, Stejskal, Vaclav, Opit, George, Yang, Qianqian, Shao, Renfu, Dowling, Damian K, Li, Zhihong

“…A single circular mitochondrial (mt) genome is a common feature across most metazoans. The mt-genome includes protein-coding genes involved in oxidative…”
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Aging: Evolution of Life Span Revisited by Dowling, Damian K.

“…A new study reports that high rates of extrinsic mortality can lead to the evolution of a longer life — a pattern opposite to that expected under the classic…”
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Sexually antagonistic evolution of mitochondrial and nuclear linkage by Radzvilavicius, Arunas, Layh, Sean, Hall, Matthew D., Dowling, Damian K., Johnston, Iain G.

“…Across eukaryotes, genes encoding bioenergetic machinery are located in both mitochondrial and nuclear DNA, and incompatibilities between the two genomes can…”
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Controlling for body size leads to inferential biases in the biological sciences by Rogell, Björn, Dowling, Damian K., Husby, Arild

“…Many traits correlate with body size. Studies that seek to uncover the ecological factors that drive evolutionary responses in traits typically examine these…”
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Ejaculate economics: testing the effects of male sexual history on the trade-off between sperm and immune function in Australian crickets by Dowling, Damian K, Simmons, Leigh W

“…Trade-offs between investment into male sexual traits and immune function provide the foundation for some of the most prominent models of sexual selection…”
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Introduction of a male-harming mitochondrial haplotype via 'Trojan Females' achieves population suppression in fruit flies by Wolff, Jonci Nikolai, Gemmell, Neil J, Tompkins, Daniel M, Dowling, Damian K

“…Pests are a global threat to biodiversity, ecosystem function, and human health. Pest control approaches are thus numerous, but their implementation costly,…”
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The cuticle inward barrier in Drosophila melanogaster is shaped by mitochondrial and nuclear genotypes and a sex-specific effect of diet by Dong, Wei, Dobler, Ralph, Dowling, Damian K, Moussian, Bernard

“…An important role of the insect cuticle is to prevent wetting (i.e., permeation of water) and also to prevent penetration of potentially harmful substances…”
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TEMPERATURE-SPECIFIC OUTCOMES OF CYTOPLASMIC-NUCLEAR INTERACTIONS ON EGG-TO-ADULT DEVELOPMENT TIME IN SEED BEETLES by Dowling, Damian K, Abiega, Katia Chávez, Arnqvist, Göran

“…The integration of the mitochondrial and nuclear genomes coordinates cellular energy production and is fundamental to life among eukaryotes. Therefore, there…”
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Cytonuclear Interactions and the Economics of Mating in Seed Beetles by Dowling, Damian K., Meerupati, Tejashwari, Arnqvist, Göran

“…Recent studies have uncovered an abundance of nonneutral cytoplasmic genetic variation within species, which suggests that we should no longer consider the…”
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Evolutionary perspectives on the links between mitochondrial genotype and disease phenotype by Dowling, Damian K.

“…Disorders of the mitochondrial respiratory chain are heterogeneous in their symptoms and underlying genetics. Simple links between candidate mutations and…”
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