Search Results - "Dowling, Andrea J"

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    Using the wax moth larva Galleria mellonella infection model to detect emerging bacterial pathogens by Hernandez, Rafael J, Hesse, Elze, Dowling, Andrea J, Coyle, Nicola M, Feil, Edward J, Gaze, Will H, Vos, Michiel

    Published in PeerJ (San Francisco, CA) (04-01-2019)
    “…Climate change, changing farming practices, social and demographic changes and rising levels of antibiotic resistance are likely to lead to future increases in…”
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    Journal Article
  3. 3

    An Unbiased Method for Clustering Bacterial Effectors Using Host Cellular Phenotypes by Dowling, Andrea J, Hodgson, David J

    Published in Applied and Environmental Microbiology (01-02-2014)
    “…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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  4. 4

    Drosophila embryos as model systems for monitoring bacterial infection in real time by Vlisidou, Isabella, Dowling, Andrea J, Evans, Iwan R, Waterfield, Nicholas, ffrench-Constant, Richard H, Wood, Will

    Published in PLoS pathogens (01-07-2009)
    “…Drosophila embryos are well studied developmental microcosms that have been used extensively as models for early development and more recently wound repair…”
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  5. 5

    The Yersinia pseudotuberculosis and Yersinia pestis toxin complex is active against cultured mammalian cells by Hares, Michelle C, Hinchliffe, Stewart J, Strong, Philippa C. R, Eleftherianos, Ioannis, Dowling, Andrea J, ffrench-Constant, Richard H, Waterfield, Nick

    “…1 University of Bath, Department of Biology and Biochemistry, Claverton Down, Bath BA2 7AY, UK 2 University of Exeter in Cornwall, Department of Biosciences,…”
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  6. 6

    Cytotoxic Fatty Acid Amides from Xenorhabdus by Proschak, Anna, Schultz, Katharina, Herrmann, Jennifer, Dowling, Andrea J., Brachmann, Alexander O., ffrench-Constant, Richard, Müller, Rolf, Bode, Helge B.

    “…Simple and bioactive: 26 acyl amides have been identified in cultures of different Xenorhabdus strains and several analogues have been synthesised. Despite…”
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  7. 7

    Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen Burkholderia pseudomallei K96243 by Dowling, Andrea J, Wilkinson, Paul A, Holden, Matthew T G, Quail, Michael A, Bentley, Stephen D, Reger, Julia, Waterfield, Nicholas R, Titball, Richard W, Ffrench-Constant, Richard H

    Published in PloS one (22-12-2010)
    “…Burkholderia pseudomallei is an important human pathogen whose infection biology is still poorly understood. The bacterium is endemic to tropical regions,…”
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  8. 8

    Evolution and Ecology of CRISPR by Westra, Edze R, Dowling, Andrea J, Broniewski, Jenny M, van Houte, Stineke

    “…CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) systems are prokaryotic adaptive immune systems that provide…”
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  9. 9

    Multiple differences in pathogen-host cell interactions following a bacterial host shift by Dowling, Andrea J., Hill, Geoffrey E., Bonneaud, Camille

    Published in Scientific reports (22-04-2020)
    “…Novel disease emergence is often associated with changes in pathogen traits that enable pathogen colonisation, persistence and transmission in the novel host…”
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  10. 10

    Mcf1 toxin induces apoptosis via the mitochondrial pathway and apoptosis is attenuated by mutation of the BH3-like domain by Dowling, Andrea J, Waterfield, Nicholas R, Hares, Michelle C, Le Goff, Gaëlle, Streuli, Charles H, ffrench-Constant, Richard H

    Published in Cellular microbiology (01-10-2007)
    “…Photorhabdus are Gram-negative, nematode-vectored bacteria that produce toxins to kill their insect hosts. The expression of one of these, Makes caterpillars…”
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  11. 11

    Dissecting the immune response to the entomopathogen Photorhabdus by Eleftherianos, Ioannis, ffrench-Constant, Richard H, Clarke, David J, Dowling, Andrea J, Reynolds, Stuart E

    Published in Trends in microbiology (Regular ed.) (01-12-2010)
    “…Bacterial pathogens either hide from or modulate the host's immune response to ensure their survival. Photorhabdus is a potent insect pathogenic bacterium that…”
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  12. 12

    Identifying Anti-host Effectors in Photorhabdus by Dowling, Andrea J

    “…The death of the insect host is an essential part of the life cycle of Photorhabdus, and as a result, this bacterium comes equipped with a dazzlingly large…”
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  13. 13

    Rhabdopeptides as Insect-Specific Virulence Factors from Entomopathogenic Bacteria by Reimer, Daniela, Cowles, Kimberly N., Proschak, Anna, Nollmann, Friederike I., Dowling, Andrea J., Kaiser, Marcel, Constant, Richard ffrench, Goodrich-Blair, Heidi, Bode, Helge B.

    “…Six novel linear peptides, named “rhabdopeptides”, have been identified in the entomopathogenic bacterium Xenorhabdus nematophila after the discovery of the…”
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  14. 14

    Novel gain of function approaches for vaccine candidate identification in Burkholderia pseudomallei by Dowling, Andrea J

    “…The Gram-negative bacterium Burkholderia pseudomallei is a serious environmental pathogen and the causative agent of the often fatal melioidosis. Disease…”
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  15. 15

    An organo-silver compound that shows antimicrobial activity against Pseudomonas aeruginosa as a monomer and plasma deposited film by Poulter, Neil, Munoz-Berbel, Xavier, Johnson, Andrew L, Dowling, Andrea J, Waterfield, Nicholas, Jenkins, A Tobias A

    “…In this communication we describe the synthesis, characterisation and plasma deposition of a novel organo-silver compound for the prevention of the growth of…”
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  16. 16

    The insecticidal toxin Makes caterpillars floppy 2 (Mcf2) shows similarity to HrmA, an avirulence protein from a plant pathogen by Waterfield, Nicholas R, Daborn, Phillip J, Dowling, Andrea J, Yang, Guowei, Hares, Michelle, ffrench-Constant, Richard H

    Published in FEMS microbiology letters (12-12-2003)
    “…The Photorhabdus luminescens W14 toxin encoding gene makes caterpillars floppy ( mcf) was discovered due to its ability to kill caterpillars when expressed in…”
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  17. 17

    Drosophila Embryos as Model Systems for Monitoring Bacterial Infection in Real Time: e1000518 by Vlisidou, Isabella, Dowling, Andrea J, Evans, Iwan R, Waterfield, Nicholas, ffrench-Constant, Richard H, Wood, Will

    Published in PLoS pathogens (01-07-2009)
    “…Drosophila embryos are well studied developmental microcosms that have been used extensively as models for early development and more recently wound repair…”
    Get full text
    Journal Article
  18. 18

    The insecticidal toxin Makes caterpillars floppy 2 (Mcf2) shows similarity to HrmA, an avirulence protein from a plant pathogen by Waterfield, Nicholas R, Daborn, Phillip J, Dowling, Andrea J, Yang, Guowei, Hares, Michelle, ffrench-Constant, Richard H

    Published in FEMS microbiology letters (01-12-2003)
    “…The Photorhabdus luminescens W14 toxin encoding gene makes caterpillars floppy (mcf) was discovered due to its ability to kill caterpillars when expressed in…”
    Get full text
    Journal Article