Search Results - "Dowidar, Naeem"

Development and verification of the PAM50-based Prosigna breast cancer gene signature assay by Wallden, Brett, Storhoff, James, Nielsen, Torsten, Dowidar, Naeem, Schaper, Carl, Ferree, Sean, Liu, Shuzhen, Leung, Samuel, Geiss, Gary, Snider, Jacqueline, Vickery, Tammi, Davies, Sherri R, Mardis, Elaine R, Gnant, Michael, Sestak, Ivana, Ellis, Matthew J, Perou, Charles M, Bernard, Philip S, Parker, Joel S

“…The four intrinsic subtypes of breast cancer, defined by differential expression of 50 genes (PAM50), have been shown to be predictive of risk of recurrence…”
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Identification of New Flagellar Genes of Salmonella enterica Serovar Typhimurium by FRYE, Jonathan, KARLINSEY, Joyce E, FELISE, Heather R, MARZOLF, Bruz, DOWIDAR, Naeem, MCCLELLAND, Michael, HUGHES, Kelly T

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Analytical validation of the PAM50-based Prosigna Breast Cancer Prognostic Gene Signature Assay and nCounter Analysis System using formalin-fixed paraffin-embedded breast tumor specimens by Nielsen, Torsten, Wallden, Brett, Schaper, Carl, Ferree, Sean, Liu, Shuzhen, Gao, Dongxia, Barry, Garrett, Dowidar, Naeem, Maysuria, Malini, Storhoff, James

“…NanoString's Prosigna™ Breast Cancer Prognostic Gene Signature Assay is based on the PAM50 gene expression signature. The test outputs a risk of recurrence…”
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Direct multiplexed measurement of gene expression with color-coded probe pairs by Geiss, Gary K, Bumgarner, Roger E, Birditt, Brian, Dahl, Timothy, Dowidar, Naeem, Dunaway, Dwayne L, Fell, H Perry, Ferree, Sean, George, Renee D, Grogan, Tammy, James, Jeffrey J, Maysuria, Malini, Mitton, Jeffrey D, Oliveri, Paola, Osborn, Jennifer L, Peng, Tao, Ratcliffe, Amber L, Webster, Philippa J, Davidson, Eric H, Hood, Leroy, Dimitrov, Krassen

“…We describe a technology, the NanoString nCounter gene expression system, which captures and counts individual mRNA transcripts. Advantages over existing…”
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Validating critical analytical variables of a multiplexed gene expression assay measuring tumor inflammation designed to predict response to anti-PD1 therapy by Popa, Simina, Church, Sarah Elizabeth, Pekker, Irena, Dowidar, Naeem, Sullivan, Amy, Ngouenet, Celine, Schaper, Carl, Ren, Xing, Danaher, Patrick, Ferree, Sean, Wallden, Brett

“…Abstract only 203 Background: The development and analytical performance of the Tumor Inflammation Signature (TIS) assay has been described previously. The TIS…”
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Verification of the analytical performance of a molecular diagnostic for response to anti-PD1 therapy on the nCounter Dx Analysis System by Wallden, Brett, Pekker, Irena, Popa, Simina, Dowidar, Naeem, Ngouenet, Celine, Sullivan, Amy, Danaher, Patrick, Mashadi-Hossein, Afshin, Liu, Mingdong, Marton, Matthew John, Ferree, Sean, Storhoff, James Justin

“…Abstract only 8 Background: Pembrolizumab is a humanized anti-PD1 antibody that is approved for use in advanced melanoma, recurrent or metastatic head and neck…”
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Analytical Validation of the nCounter®-based Lymphoma Subtyping Test (LST) for Cell-of-Origin (COO) Identification in Formalin-Fixed Paraffin-Embedded (FFPE) Diffuse Large B-Cell Lymphoma (DLBCL) Specimens by Chen, Ning, Dennis, Shannon, Danaher, Patrick, Wallden, Brett, Hood, Tressa, Ren, Xing, Liu, Mingdong, Dowidar, Naeem, Sullivan, Amy, Haffner, Taryn, Cesano, Alessandra, Ferree, Sean, Storhoff, James

“…Introduction: Diffuse large B-cell lymphoma (DLBCL) is an aggressive form of non-Hodgkin’s lymphoma with two distinct molecular subtypes defined by…”
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Analytical Performance of Nanostring's Companion Diagnostic (CDx) Lymphoma Subtyping Test (LST) with Diffuse Large B-Cell Lymphoma Core Needle Biopsy Samples by Storhoff, James, Wallden, Brett, Braziel, Rita M., Thieblemont, Catherine, Hood, Tressa, Ravi, Harini, Dennis, Shannon, Dowidar, Naeem, Danaher, Patrick, Dunlap, Jennifer, Briere, Josette, de Kerviler, Eric, Ferree, Sean

“…Background: Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin's lymphoma with two distinct molecular cell-of-origin (COO) subtypes known as…”
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Development of the molecular diagnostic (MDx) DLBCL Lymphoma Subtyping Test (LST) on the nCounter Analysis System by Wallden, Brett, Ferree, Sean, Ravi, Harini, Dowidar, Naeem, Hood, Tressa, Danaher, Patrick, Mashadi-Hossein, Afshin, Wright, George, Schaper, Carl, Storhoff, James Justin

“…Abstract only…”
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Development and analytical performance of a molecular diagnostic for anti-PD1 response on the nCounter Dx Analysis System by Wallden, Brett, Pekker, Irena, Popa, Simina, Dowidar, Naeem, Sullivan, Amy, Hood, Tressa, Danaher, Patrick, Mashadi-Hossein, Afshin, Lunceford, Jared K., Marton, Matthew John, Chang, Ken C. N., Ferree, Sean, Storhoff, James Justin

“…Abstract only…”
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Prosigna (PAM50) to predict response to neoadjuvant chemotherapy (NAC) in HR+/HER2- early breast cancer (EBC) patients by Jimenez Rodriguez, Begona, Lavado Fernandez, Ana Isabel, Ribelles, Nuria, Sanchez-Rovira, Pedro, Vicioso, Luis, Alvarez, Martina, de Luque, Vanessa, Ramirez Tortosa, Cesar, Buckingham, Wesley, Schaper, Carl, Jeiranian, Arthur, Dowidar, Naeem, Ferree, Sean, Villar, Ester, Zarcos, Irene, Sanchez-Muñoz, Alfonso, Gonzalez-Hermoso, Carlos, Llacer Perez, Casilda, Prat, Aleix, Alba, Emilio

“…Abstract only…”
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Blinded independent validation of the PAM50-based Chemo-Endocrine Sensitivity Predictor (CESP) in hormone receptor (HR)-positive/HER2-negative (HR+/HER2-) breast cancer following neoadjuvant chemotherapy (NAC) by Prat, Aleix, Jimenez Rodriguez, Begona, Sánchez Rovira, Pedro, Alvarez, Martina, Vicioso, Luis, de Luque, Vanessa, Fernandez-Sousa, Cristina, Parrado, M Rosario Chica, Santonja, Angela, Ramirez Tortosa, Cesar, Lavado Fernandez, Ana Isabel, Perez Ruiz, Elisabeth, Gonzalez-Hermoso, Carlos, Buckingham, Wesley, Dowidar, Naeem, Ferree, Sean, Jeiranian, Arthur, Schaper, Carl, Ribelles, Nuria, Alba, Emilio

“…Abstract only…”
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Abstract LB-327: Analytical performance of the nCounter analysis system for gene expression cancer signatures by Ferree, Sean, Bernard, Philip S., Dowidar, Naeem, Ellis, Matthew, Maysuria, Malini, Nielsen, Torsten, Payandeh, Emily, Parker, Joel, Perou, Charles M., Storhoff, James, Wallden, Brett

“…Background: The nCounter Analysis System is a platform for performing highly multiplexed, digital quantification of hundreds of different nucleic acid species…”
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Erratum: Corrigendum: Direct multiplexed measurement of gene expression with color-coded probe pairs by Geiss, Gary K, Bumgarner, Roger E, Birditt, Brian, Dahl, Timothy, Dowidar, Naeem, Dunaway, Dwayne L, Fell, H Perry, Ferree, Sean, George, Renee D, Grogan, Tammy, James, Jeffrey J, Maysuria, Malini, Mitton, Jeffrey D, Oliveri, Paola, Osborn, Jennifer L, Peng, Tao, Ratcliffe, Amber L, Webster, Philippa J, Davidson, Eric H, Hood, Leroy

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Corrigendum: Direct multiplexed measurement of gene expression with color-coded probe pairs by Geiss, Gary K, Bumgarner, Roger E, Birditt, Brian, Dahl, Timothy, Dowidar, Naeem, Dunaway, Dwayne L, Fell, H Perry, Ferree, Sean, George, Renee D, Grogan, Tammy, James, Jeffrey J, Maysuria, Malini, Mitton, Jeffrey D, Oliveri, Paola, Osborn, Jennifer L, Peng, Tao, Ratcliffe, Amber L, Webster, Philippa J, Davidson, Eric H, Hood, Leroy

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Correction: Corrigendum: Direct multiplexed measurement of gene expression with color-coded probe pairs by Geiss, Gary K, Bumgarner, Roger E, Birditt, Brian, Dahl, Timothy, Dowidar, Naeem, Dunaway, Dwayne L, Fell, H Perry, Ferree, Sean, George, Renee D, Grogan, Tammy, James, Jeffrey J, Maysuria, Malini, Mitton, Jeffrey D, Oliveri, Paola, Osborn, Jennifer L, Peng, Tao, Ratcliffe, Amber L, Webster, Philippa J, Davidson, Eric H, Hood, Leroy

“…Nat. Biotechnol. 26, 317–325 (2008); published online 17 February 2008, corrected after print 16 May 2008 In the version of this article initially published,…”
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