Search Results - "Dowd, Andrew"

Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae by Mitchell, Sara N, Rigden, Daniel J, Dowd, Andrew J, Lu, Fang, Wilding, Craig S, Weetman, David, Dadzie, Samuel, Jenkins, Adam M, Regna, Kimberly, Boko, Pelagie, Djogbenou, Luc, Muskavitch, Marc A T, Ranson, Hilary, Paine, Mark J I, Mayans, Olga, Donnelly, Martin J

“…The development of resistance to insecticides has become a classic exemplar of evolution occurring within human time scales. In this study we demonstrate how…”
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A Novel Point-of-care Ultrasound Curriculum for Air Critical Care Personnel by O'Connor, Laurel, Beth-Urhoy, Matthew, Allegra, Stephen, Dowd, Andrew, Nordberg, Alexandra, Boardman, Timothy, Gleeson, Timothy, Lindsay, Robert

“…Point-of care-ultrasound (POCUS) has become ubiquitous in emergency medicine practice for the management of emergent pathophysiology. There is growing interest…”
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A simple colorimetric assay for specific detection of glutathione-S transferase activity associated with DDT resistance in mosquitoes by Morou, Evangelia, Dowd, Andrew J, Rajatileka, Shavanti, Steven, Andrew, Hemingway, Janet, Ranson, Hilary, Paine, Mark, Vontas, John

“…Insecticide-based methods represent the most effective means of blocking the transmission of vector borne diseases. However, insecticide resistance poses a…”
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Proteomic analysis of isolated membrane fractions from superinvasive cancer cells by Dowling, Paul, Meleady, Paula, Dowd, Andrew, Henry, Michael, Glynn, Sharon, Clynes, Martin

“…The superinvasive phenotype exhibited by paclitaxel-selected variants of an in vitro invasive clonal population of the human cancer cell line, MDA-MB-435S were…”
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A dehydrochlorinase-based pH change assay for determination of DDT in sprayed surfaces by Morou, Evangelia, Ismail, Hanafy M., Dowd, Andrew J., Hemingway, Janet, Labrou, Nikos, Paine, Mark, Vontas, John

“…A glutathione S-transferase (GST) from the mosquito Aedes aegypti ( aagste2), selected in the field as a major metabolic resistance enzyme for this parasite…”
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Enzyme Assay Methods to Validate DIGE Proteomics Data by Dowd, Andrew

“…Enzyme activity assay methods can be used to corroborate the results generated by Difference Gel Electrophoresis (DIGE) proteomic experiments. Two assay…”
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Elucidating Cellular Metabolism and Protein Difference Data from DIGE Proteomics Experiments Using Enzyme Assays by Dowd, Andrew

“…Assays for measuring enzyme activity can be useful tools for proteomics applications. Enzyme testing can be performed to validate an experimental system prior…”
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A simple glutathione transferase-based colorimetric endpoint assay for insecticide detection by Dowd, Andrew J., Steven, Andrew, Morou, Evangelia, Hemingway, Janet, Vontas, John, Paine, Mark J.I.

“…The natural ability of the detoxification enzymes glutathione transferases (GSTs) to interact with xenobiotics can be used for the production of colorimetric…”
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Development of a colourimetric pH assay for the quantification of pyrethroids based on glutathione-S-transferase by Dowd, Andrew J., Morou, Evangelia, Steven, Andrew, Ismail, Hanafy M., Labrou, Nikolaos, Hemingway, Janet, Paine, Mark J.I., Vontas, John

“…Recombinant glutathione-S-transferases (GSTs) can be used as analytical tools for the development of simple insecticide quantification assays. This assay…”
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Climate Change Increases the Potential for Extreme Wildfires by Di Virgilio, Giovanni, Evans, Jason P., Blake, Stephanie A. P., Armstrong, Matthew, Dowdy, Andrew J., Sharples, Jason, McRae, Rick

“…Pyrocumulonimbus (pyroCb) wildfires cause devastation in many regions globally. Given that fire‐atmosphere coupling is associated with pyroCbs, future changes…”
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Femoral Arterial Doppler Use During Active Cardiopulmonary Resuscitation by Gaspari, Romolo J., Lindsay, Robert, Dowd, Andrew, Gleeson, Timothy

“…This study explored femoral arterial Doppler during active cardiopulmonary resuscitation (CPR) to identify and characterize the resumptions of cardiac activity…”
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Stability studies on the cathepsin L proteinase of the helminth parasite , Fasciola hepatica by Dowd, Andrew J, Dooley, Mary, Fágáin, Ciaránō, Dalton, John P

“…Fasciola hepatica, the liver fluke, secretes a cathepsin L cysteine proteinase. The enzyme is active over the pH range 5–9 and is remarkably stable at 37°C, pH…”
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Purification of a diagnostic, secreted cysteine protease-like protein from the hookworm Ancylostoma caninum by Loukas, Alex, Dowd, Andrew J, Prociv, Paul, Brindley, Paul J

“…The enteric infection of humans with the canine hookworm Ancylostoma caninum varies in its clinical presentation, ranging from asymptomatic to eosinophilic…”
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Collagenase in the treatment of Dupuytren's disease: an in vitro study by Starkweather, K D, Lattuga, S, Hurst, L C, Badalamente, M A, Guilak, F, Sampson, S P, Dowd, A, Wisch, D

“…The effects of clostridial collagenase on the tensile strength of Dupuytren's cords was studied in vitro to assess its potential efficacy as an agent for…”
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Isolation of a cDNA encoding Fasciola hepatica cathepsin L2 and functional expression in Saccharomyces cerevisiae by Dowd, Andrew J, Tort, Jose, Roche, Leda, Ryan, Thecla, Dalton, John P

“…Cathepsin L2 is a major cysteine proteinase secreted by adult Fasciola hepatica. The enzyme differs from other reported cathepsin Ls in that it can cleave…”
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Cathepsin L proteinase secreted by Fasciola hepatica in vitro prevents antibody-mediated eosinophil attachment to newly excysted juveniles by Carmona, C, Dowd, A J, Smith, A M, Dalton, J P

“…Cathepsin L-like activity was demonstrated in the excretory/secretory (E/S) products of Fasciola hepatica newly excysted juveniles (NEJ), 3-week-old,…”
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Genome sequences of two isolates of the yeast Candida zeylanoides : UCD849 from soil in Ireland, and AWD from an African wild dog by McLaughlin, Richard W, Hession, Conor, Bergin, Sean, Cosgrove, Aoife, Dowd, Andrew, Garvey, Niall, Litovskich, Gabrielle, Osaigbovo, Evita, Popa, Denis, Thuku, Cynthia, Butler, Geraldine, Wolfe, Kenneth H, Byrne, Kevin P

“…We report genome sequences of two new isolates of the budding yeast . Strain UCD849 from soil in Ireland was assembled into eight complete chromosomes. Strain…”
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Secretion of cysteine proteinase activity by the zoonotic hookworm Ancylostoma caninum by Dowd, A J, Dalton, J P, Loukas, A C, Prociv, P, Brindley, P J

“…The zoonotic hookworm, Ancylostoma caninum, probably induces human eosinophilic enteritis by inducing allergic responses to its secretions. This species is…”
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Purification of a cathepsin L-like proteinase secreted by adult Fasciola hepatica by Smith, A M, Dowd, A J, McGonigle, S, Keegan, P S, Brennan, G, Trudgett, A, Dalton, J P

“…A cysteine proteinase released in vitro by Fasciola hepatica was purified to homogeneity by Sephacryl S-200 gel filtration chromatography followed by…”
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Proteomic screening of glucose-responsive and glucose non-responsive MIN-6 beta cells reveals differential expression of proteins involved in protein folding, secretion and oxidative stress by Dowling, Paul, O'Driscoll, Lorraine, O'Sullivan, Finbarr, Dowd, Andrew, Henry, Michael, Jeppesen, Per Bendix, Meleady, Paula, Clynes, Martin

“…The glucose‐sensitive insulin‐secretion (GSIS) phenotype is relatively unstable in long‐term culture of beta cells. The purpose of this study was to…”
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