Search Results - "Dow, Michelle"

An evaluation of copy number variation detection tools for cancer using whole exome sequencing data by Zare, Fatima, Dow, Michelle, Monteleone, Nicholas, Hosny, Abdelrahman, Nabavi, Sheida

“…Recently copy number variation (CNV) has gained considerable interest as a type of genomic/genetic variation that plays an important role in disease…”
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The Emerging Potential for Network Analysis to Inform Precision Cancer Medicine by Ozturk, Kivilcim, Dow, Michelle, Carlin, Daniel E., Bejar, Rafael, Carter, Hannah

“…Precision cancer medicine promises to tailor clinical decisions to patients using genomic information. Indeed, successes of drugs targeting genetic alterations…”
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Integrative genomic analysis of mouse and human hepatocellular carcinoma by Dow, Michelle, Pyke, Rachel M., Tsui, Brian Y., Alexandrov, Ludmil B., Nakagawa, Hayato, Taniguchi, Koji, Seki, Ekihiro, Harismendy, Olivier, Shalapour, Shabnam, Karin, Michael, Carter, Hannah, Font-Burgada, Joan

“…Cancer genomics has enabled the exhaustive molecular characterization of tumors and exposed hepatocellular carcinoma (HCC) as among the most complex cancers…”
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In vitro evolution and whole genome analysis to study chemotherapy drug resistance in haploid human cells by Jado, Juan Carlos, Dow, Michelle, Carolino, Krypton, Klie, Adam, Fonseca, Gregory J., Ideker, Trey, Carter, Hannah, Winzeler, Elizabeth A.

“…In vitro evolution and whole genome analysis has proven to be a powerful method for studying the mechanism of action of small molecules in many haploid…”
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Food-Intake Normalization of Dysregulated Fatty Acids in Women with Anorexia Nervosa by Nguyen, Nhien, Dow, Michelle, Woodside, Blake, German, J Bruce, Quehenberger, Oswald, Shih, Pei-An Betty

“…Anorexia nervosa (AN) is a psychiatric disorder affected by psychological, environmental, and biological factors. Individuals with AN avoid high-fat,…”
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Genome privacy: challenges, technical approaches to mitigate risk, and ethical considerations in the United States by Wang, Shuang, Jiang, Xiaoqian, Singh, Siddharth, Marmor, Rebecca, Bonomi, Luca, Fox, Dov, Dow, Michelle, Ohno‐Machado, Lucila

“…Accessing and integrating human genomic data with phenotypes are important for biomedical research. Making genomic data accessible for research purposes,…”
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Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation by Zhou, Yixuan, Bastian, Ingmar Niels, Long, Mark D., Dow, Michelle, Li, Weihua, Liu, Tao, Ngu, Rachael Katie, Antonucci, Laura, Huang, Jian Yu, Phung, Qui T., Zhao, Xi-he, Banerjee, Sourav, Lin, Xue-Jia, Wang, Hongxia, Dang, Brian, Choi, Sylvia, Karin, Daniel, Su, Hua, Ellisman, Mark H., Jamieson, Christina, Bosenberg, Marcus, Cheng, Zhang, Haybaeck, Johannes, Kenner, Lukas, Fisch, Kathleen M., Bourgon, Richard, Hernandez, Genevive, Lill, Jennie R., Liu, Song, Carter, Hannah, Mellman, Ira, Karin, Michael, Shalapour, Shabnam

“…Many cancers evade immune rejection by suppressing major histocompatibility class I (MHC-I) antigen processing and presentation (AgPP). Such cancers do not…”
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Immune DNA signature of T-cell infiltration in breast tumor exomes by Levy, Eric, Marty, Rachel, Gárate Calderón, Valentina, Woo, Brian, Dow, Michelle, Armisen, Ricardo, Carter, Hannah, Harismendy, Olivier

“…Tumor infiltrating lymphocytes (TILs) have been associated with favorable prognosis in multiple tumor types. The Cancer Genome Atlas (TCGA) represents the…”
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Increasing metadata coverage of SRA BioSample entries using deep learning-based named entity recognition by Klie, Adam, Tsui, Brian Y, Mollah, Shamim, Skola, Dylan, Dow, Michelle, Hsu, Chun-Nan, Carter, Hannah

“…High-quality metadata annotations for data hosted in large public repositories are essential for research reproducibility and for conducting fast, powerful and…”
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Extracting allelic read counts from 250,000 human sequencing runs in Sequence Read Archive by Tsui, Brian, Dow, Michelle, Skola, Dylan, Carter, Hannah

“…The Sequence Read Archive (SRA) contains over one million publicly available sequencing runs from various studies using a variety of sequencing library…”
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PREMIX: PRivacy-preserving EstiMation of Individual admiXture by Chen, Feng, Dow, Michelle, Ding, Sijie, Lu, Yao, Jiang, Xiaoqian, Tang, Hua, Wang, Shuang

“…In this paper we proposed a framework: PRivacy-preserving EstiMation of Individual admiXture (PREMIX) using Intel software guard extensions (SGX). SGX is a…”
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Integrative Multi-Omics Analysis to Understand Cancer and Anticancer Therapy by Dow, Michelle Ting

“…Precision cancer medicine promises better treatments to a disease as complex and heterogenous as cancer. Many anti-cancer therapies are beneficial to only a…”
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The RUNX1-ETO target gene RASSF2 suppresses t(8;21) AML development and regulates Rac GTPase signaling by Stoner, Samuel A., Liu, Katherine Tin Heng, Andrews, Elizabeth T., Liu, Mengdan, Arimoto, Kei-Ichiro, Yan, Ming, Davis, Amanda G., Weng, Stephanie, Dow, Michelle, Xian, Su, DeKelver, Russell C., Carter, Hannah, Zhang, Dong-Er

“…Large-scale chromosomal translocations are frequent oncogenic drivers in acute myeloid leukemia (AML). These translocations often occur in critical…”
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A mechanistic model linking insect (Hydropsychidae) silk nets to incipient sediment motion in gravel-bedded streams by Albertson, Lindsey K., Sklar, Leonard S., Pontau, Patricia, Dow, Michelle, Cardinale, Bradley J.

“…Plants and animals affect stream morphodynamics across a range of scales, yet including biological traits of organisms in geomorphic process models remains a…”
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Learning together: new partnerships for new times by Senge, Peter M., Dow, Michelle, Neath, Gavin

“…Purpose - The purpose of this research is to provide an overview of the learning that has emerged from two initiatives in which a multinational company,…”
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