Search Results - "Dow, Julian A. T."

A nutrient-responsive hormonal circuit mediates an inter-tissue program regulating metabolic homeostasis in adult Drosophila by Koyama, Takashi, Terhzaz, Selim, Naseem, Muhammad T., Nagy, Stanislav, Rewitz, Kim, Dow, Julian A. T., Davies, Shireen A., Halberg, Kenneth V.

“…Animals maintain metabolic homeostasis by modulating the activity of specialized organs that adjust internal metabolism to external conditions. However, the…”
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Mechanism and function of Drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor by Terhzaz, Selim, Cabrero, Pablo, Robben, Joris H, Radford, Jonathan C, Hudson, Brian D, Milligan, Graeme, Dow, Julian A T, Davies, Shireen-A

“…The capa peptide receptor, capaR (CG14575), is a G-protein coupled receptor (GPCR) for the D. melanogaster capa neuropeptides, Drm-capa-1 and -2 (capa-1 and…”
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FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data by Leader, David P, Krause, Sue A, Pandit, Aniruddha, Davies, Shireen A, Dow, Julian A T

“…Abstract FlyAtlas 2 (www.flyatlas2.org) is part successor, part complement to the FlyAtlas database and web application for studying the expression of the…”
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Transport proteins NHA1 and NHA2 are essential for survival, but have distinct transport modalities by Chintapalli, Venkateswara R., Kato, Akira, Henderson, Louise, Hirata, Taku, Woods, Debra J., Overend, Gayle, Davies, Shireen A., Romero, Michael F., Dow, Julian A. T.

“…The cation/proton antiporter (CPA) family includes the well-known sodium/proton exchanger (NHE; SLC9A) family of Na⁺/H⁺ exchangers, and the more recently…”
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Functional correlates of positional and gender-specific renal asymmetry in Drosophila by Chintapalli, Venkateswara R, Terhzaz, Selim, Wang, Jing, Al Bratty, Mohammed, Watson, David G, Herzyk, Pawel, Davies, Shireen A, Dow, Julian A T

“…In humans and other animals, the internal organs are positioned asymmetrically in the body cavity, and disruption of this body plan can be fatal in humans. The…”
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Assessment of neuropeptide binding sites and the impact of biostable kinin and CAP2b analogue treatment on aphid (Myzus persicae and Macrosiphum rosae) stress tolerance by Alford, Lucy, Marley, Richard, Dornan, Anthony, Pierre, Jean‐Sébastien, Dow, Julian AT, Nachman, Ronald J, Davies, Shireen A

“…BACKGROUND Neuropeptides are regulators of critical life processes in insects and, due to their high specificity, represent potential targets in the…”
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Identification of two partners from the bacterial Kef exchanger family for the apical plasma membrane V-ATPase of Metazoa by Day, Jonathan P, Wan, Susan, Allan, Adrian K, Kean, Laura, Davies, Shireen A, Gray, Joe V, Dow, Julian A.T

“…The vital task of vectorial solute transport is often energised by a plasma membrane, proton-motive V-ATPase. However, its proposed partner, an apical…”
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Drosophila melanogaster: a simple genetic model of kidney structure, function and disease by Dow, Julian A. T., Simons, Matias, Romero, Michael F.

“…Although the genetic basis of many kidney diseases is being rapidly elucidated, their experimental study remains problematic owing to the lack of suitable…”
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Developmental expression and biophysical characterization of a Drosophila melanogaster aquaporin by Kaufmann, Nancy, Mathai, John C, Hill, Warren G, Dow, Julian A T, Zeidel, Mark L, Brodsky, Jeffrey L

“…Aquaporins (AQPs) accelerate the movement of water and other solutes across biological membranes, yet the molecular mechanisms of each AQP's transport function…”
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Publisher Correction: Drosophila melanogaster: a simple genetic model of kidney structure, function and disease by Dow, Julian A. T., Simons, Matias, Romero, Michael F.

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A new role for a classical gene: white transports cyclic GMP by Evans, Jennifer M, Day, Jonathan P, Cabrero, Pablo, Dow, Julian A T, Davies, Shireen-Anne

“…Guanosine 3'-5' cyclic monophosphate (cGMP) and adenosine 3'-5' cyclic monophosphate (cAMP) are important regulators of cell and tissue function. However, cGMP…”
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Data-mining the FlyAtlas online resource to identify core functional motifs across transporting epithelia by Chintapalli, Venkateswara R, Wang, Jing, Herzyk, Pawel, Davies, Shireen A, Dow, Julian A T

“…Comparative analysis of tissue-specific transcriptomes is a powerful technique to uncover tissue functions. Our FlyAtlas.org provides authoritative gene…”
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Integrative Physiology and Functional Genomics of Epithelial Function in a Genetic Model Organism by DOW, JULIAN A. T, DAVIES, SHIREEN A

“…Division of Molecular Genetics, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow, United Kingdom Dow, Julian A. T, and Shireen A…”
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Insights into the Malpighian tubule from functional genomics by Dow, Julian A T

“…Classical physiological study of the Malpighian tubule has led to a detailed understanding of fluid transport and its control across several species. With the…”
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Integrative physiology, functional genomics and the phenotype gap: a guide for comparative physiologists by Dow, Julian A T

“…Classical, curiosity-led comparative physiology finds itself at a crossroads. Major funding for classical physiology is becoming harder to find, as grant…”
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Specialized stellate cells offer a privileged route for rapid water flux in Drosophila renal tubule by Cabrero, Pablo, Terhzaz, Selim, Dornan, Anthony J., Ghimire, Saurav, Holmes, Heather L., Turin, Daniel R., Romero, Michael F., Davies, Shireen A., Dow, Julian A. T.

“…Insects are highly successful, in part through an excellent ability to osmoregulate. The renal (Malpighian) tubules can secrete fluid faster on a per-cell…”
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Developmental, Molecular, and Transport Biology of Malpighian Tubules by Beyenbach, Klaus W, Skaer, Helen, Dow, Julian A.T

“…Molecular biology is reaching new depths in our understanding of the development and physiology of Malpighian tubules. In Diptera, Malpighian tubules derive…”
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Tracing the evolutionary origins of insect renal function by Halberg, Kenneth A., Terhzaz, Selim, Cabrero, Pablo, Davies, Shireen A., Dow, Julian A. T.

“…Knowledge on neuropeptide receptor systems is integral to understanding animal physiology. Yet, obtaining general insight into neuropeptide signalling in a…”
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Insect capa neuropeptides impact desiccation and cold tolerance by Terhzaz, Selim, Teets, Nicholas M., Cabrero, Pablo, Henderson, Louise, Ritchie, Michael G., Nachman, Ronald J., Dow, Julian A. T., Denlinger, David L., Davies, Shireen-A.

“…The success of insects is linked to their impressive tolerance to environmental stress, but little is known about how such responses are mediated by the…”
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Towards a platform for the metabonomic profiling of different strains of Drosophila melanogaster using liquid chromatography-Fourier transform mass spectrometry by Kamleh, Muhammad A, Hobani, Yahya, Dow, Julian A.T, Zheng, Liang, Watson, David G

“…A platform based on hydrophilic interaction chromatography in combination with Fourier transform mass spectrometry was developed in order to carry out…”
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