Search Results - "Dovey, Cole M."
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RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity
Published in Molecular cell (20-11-2014)“…Receptor-interacting protein kinase 3 (RIP3 or RIPK3) has emerged as a central player in necroptosis and a potential target to control inflammatory disease…”
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A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity
Published in Cell reports (Cambridge) (05-02-2019)“…The tripeptide glutathione suppresses the iron-dependent, non-apoptotic cell death process of ferroptosis. How glutathione abundance is regulated in the cell…”
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Honey bee Royalactin unlocks conserved pluripotency pathway in mammals
Published in Nature communications (04-12-2018)“…Royal jelly is the queen-maker for the honey bee Apis mellifera , and has cross-species effects on longevity, fertility, and regeneration in mammals. Despite…”
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MLKL Requires the Inositol Phosphate Code to Execute Necroptosis
Published in Molecular cell (07-06-2018)“…Necroptosis is an important form of lytic cell death triggered by injury and infection, but whether mixed lineage kinase domain-like (MLKL) is sufficient to…”
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Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1
Published in Cell death & disease (26-07-2018)“…Necroptosis complements apoptosis as a host defense pathway to stop virus infection. Herpes simplex virus shows a propensity to trigger necroptosis of mouse…”
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Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites
Published in Cell chemical biology (20-06-2019)“…Necroptosis is an inflammatory form of programmed cell death executed through plasma membrane rupture by the pseudokinase mixed lineage kinase domain-like…”
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7
RIP3 induces apoptosis independent of pro-necrotic kinase activity
Published in Molecular cell (20-11-2014)“…Receptor interacting protein kinase 3 (RIP3 or RIPK3) has emerged as a central player in necroptosis and a potential target to control inflammatory disease…”
Get full text
Journal Article