Search Results - "Dovey, Cole M."

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    A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity by Cao, Jennifer Yinuo, Poddar, Aunoy, Magtanong, Leslie, Lumb, Jennifer H., Mileur, Trevor R., Reid, Michael A., Dovey, Cole M., Wang, Jin, Locasale, Jason W., Stone, Everett, Cole, Susan P.C., Carette, Jan E., Dixon, Scott J.

    Published in Cell reports (Cambridge) (05-02-2019)
    “…The tripeptide glutathione suppresses the iron-dependent, non-apoptotic cell death process of ferroptosis. How glutathione abundance is regulated in the cell…”
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    Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1 by Guo, Hongyan, Gilley, Ryan P., Fisher, Amanda, Lane, Rebecca, Landsteiner, Vanessa J., Ragan, Katherine B., Dovey, Cole M., Carette, Jan E., Upton, Jason W., Mocarski, Edward S., Kaiser, William J.

    Published in Cell death & disease (26-07-2018)
    “…Necroptosis complements apoptosis as a host defense pathway to stop virus infection. Herpes simplex virus shows a propensity to trigger necroptosis of mouse…”
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    Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites by McNamara, Dan E, Dovey, Cole M, Hale, Andrew T, Quarato, Giovanni, Grace, Christy R, Guibao, Cristina D, Diep, Jonathan, Nourse, Amanda, Cai, Casey R, Wu, Hong, Kalathur, Ravi C, Green, Douglas R, York, John D, Carette, Jan E, Moldoveanu, Tudor

    Published in Cell chemical biology (20-06-2019)
    “…Necroptosis is an inflammatory form of programmed cell death executed through plasma membrane rupture by the pseudokinase mixed lineage kinase domain-like…”
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