Search Results - "Douville, Nicholas"

Quantitative Analysis of Molecular Absorption into PDMS Microfluidic Channels by Wang, Jack D., Douville, Nicholas J., Takayama, Shuichi, ElSayed, Mohamed

“…Microfluidic devices fabricated using poly(dimethylsiloxane) (PDMS) polymer are routinely used for in vitro cell culture for a wide range of cellular assays…”
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Perioperative Acute Kidney Injury: Diagnosis, Prediction, Prevention, and Treatment by Douville, Nicholas J., Mathis, Michael, Kheterpal, Sachin, Heung, Michael, Schaub, Jennifer, Naik, Abhijit, Kretzler, Matthias

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Comparison of ultrasound-guided core biopsy versus fine-needle aspiration biopsy in the evaluation of salivary gland lesions by Douville, Nicholas J., Bradford, Carol R.

“…Ultrasound‐guided core biopsy provides many benefits compared with fine‐needle aspiration cytology and has begun to emerge as part of the diagnostic work‐up…”
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Intraoperative Mechanical Ventilation and Postoperative Pulmonary Complications after Cardiac Surgery by Mathis, Michael R, Duggal, Neal M, Likosky, Donald S, Haft, Jonathan W, Douville, Nicholas J, Vaughn, Michelle T, Maile, Michael D, Blank, Randal S, Colquhoun, Douglas A, Strobel, Raymond J, Janda, Allison M, Zhang, Min, Kheterpal, Sachin, Engoren, Milo C

“…BACKGROUND:Compared with historic ventilation strategies, modern lung-protective ventilation includes lower tidal volumes (VT), lower driving pressures, and…”
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Intraoperative risk factors of acute kidney injury after liver transplantation by Berkowitz, Rachel J., Engoren, Milo C., Mentz, Graciela, Sharma, Pratima, Kumar, Sathish S., Davis, Ryan, Kheterpal, Sachin, Sonnenday, Christopher J., Douville, Nicholas J.

“…Acute kidney injury (AKI) is one of the most common complications of liver transplantation (LT). We examined the impact of intraoperative management on risk…”
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Clinically applicable approach for predicting mechanical ventilation in patients with COVID-19 by Douville, Nicholas J, Douville, Christopher B, Mentz, Graciela, Mathis, Michael R, Pancaro, Carlo, Tremper, Kevin K, Engoren, Milo

“…Patients with coronavirus disease 2019 (COVID-19) requiring mechanical ventilation have high mortality and resource utilisation. The ability to predict which…”
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Combination of fluid and solid mechanical stresses contribute to cell death and detachment in a microfluidic alveolar model by Douville, Nicholas J, Zamankhan, Parsa, Tung, Yi-Chung, Li, Ran, Vaughan, Benjamin L, Tai, Cheng-Feng, White, Joshua, Christensen, Paul J, Grotberg, James B, Takayama, Shuichi

“…Studies using this micro-system demonstrated significant morphological differences between alveolar epithelial cells (transformed human alveolar epithelial…”
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Universal intraoperative systemic heparin administration during liver transplantation: A case series by Diaz, Sarah, VanWinkle, Callie, Roney, Emily, Kumar, Sathish S, Douville, Nicholas J, Englesbe, Michael, Sonnenday, Christopher J, Waits, Seth, Schaefer, Sara L

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Association of Intraoperative Ventilator Management With Postoperative Oxygenation, Pulmonary Complications, and Mortality by Douville, Nicholas J, Jewell, Elizabeth S, Duggal, Neal, Blank, Ross, Kheterpal, Sachin, Engoren, Milo C, Mathis, Michael R

“…BACKGROUND:“Lung-protective ventilation” describes a ventilation strategy involving low tidal volumes (VTs) and/or low driving pressure/plateau pressure and…”
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ASSOCIATION OF CARDIOPULMONARY HEMODYNAMICS AND OUTCOMES IN PULMONARY HYPERTENSION FOLLOWING KIDNEY TRANSPLANT: A MULTICENTER RETROSPECTIVE COHORT STUDY by JOSE, ARUN, KUMAR, SATHISH, GORELIK, LEONID, HUT FRIEDMAN, SAMUEL, FLORES, ANTOLIN, SESE, DENISE A, VINZANI, MICHAEL, DOUVILLE, NICHOLAS, PATEL, AKSHAR, ARGULA, RAHUL G, JONES, COURTNEY, BHAVE, NICOLE M, ELWING, JEAN M.

“…Pulmonary Hypertension (PH) frequently complicates the evaluation of kidney transplant (KT) candidates, and is associated with increased adverse outcomes…”
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Polygenic Score for the Prediction of Postoperative Nausea and Vomiting: A Retrospective Derivation and Validation Cohort Study by Douville, Nicholas J, Bastarache, Lisa, He, Jing, Wu, Kuan-Han H, Vanderwerff, Brett, Bertucci-Richter, Emily, Hornsby, Whitney E, Lewis, Adam, Jewell, Elizabeth S, Kheterpal, Sachin, Shah, Nirav, Mathis, Michael, Engoren, Milo C, Douville, Christopher B, Surakka, Ida, Willer, Cristen, Kertai, Miklos D

“…Postoperative nausea and vomiting (PONV) is a key driver of unplanned admission and patient satisfaction following surgery. Because traditional risk factors do…”
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Intraoperative risk factors of acute kidney injury following liver transplantation by Berkowitz, Rachel J., Engoren, Milo C., Mentz, Graciela, Sharma, Pratima, Kumar, Sathish S., Davis, Ryan, Kheterpal, Sachin, Sonnenday, Christopher J., Douville, Nicholas J.

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Genetic mutations associated with susceptibility to perioperative complications in a longitudinal biorepository with integrated genomic and electronic health records by Douville, Nicholas J, Kheterpal, Sachin, Engoren, Milo, Mathis, Michael, Mashour, George A, Hornsby, Whitney E, Willer, Cristen J, Douville, Christopher B

“…Existing genetic information can be leveraged to identify patients with susceptibilities to conditions that might impact their perioperative care, but…”
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Genetic variants associated with sepsis by Engoren, Milo, Jewell, Elizabeth S, Douville, Nicholas, Moser, Stephanie, Maile, Michael D, Bauer, Melissa E

“…The variable presentations and different phenotypes of sepsis suggest that risk of sepsis comes from many genes each having a small effect. The cumulative…”
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Early Detection of Heart Failure With Reduced Ejection Fraction Using Perioperative Data Among Noncardiac Surgical Patients: A Machine-Learning Approach by Mathis, Michael R., Engoren, Milo C., Joo, Hyeon, Maile, Michael D., Aaronson, Keith D., Burns, Michael L., Sjoding, Michael W., Douville, Nicholas J., Janda, Allison M., Hu, Yaokun, Najarian, Kayvan, Kheterpal, Sachin

“…Heart failure with reduced ejection fraction (HFrEF) is a condition imposing significant health care burden. Given its syndromic nature and often insidious…”
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Volume of packed red blood cells and fresh frozen plasma is associated with intraoperative hypocalcaemia during large volume intraoperative transfusion by Douville, Nicholas J., Davis, Ryan, Jewell, Elizabeth, Colquhoun, Douglas A., Ramachandran, Satya Krishna, Engoren, Milo C., Picton, Paul

“…Background Severe hypocalcaemia is associated with increased transfusion in the trauma population. Furthermore, trauma patients developing severe hypocalcaemia…”
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Genetic predisposition may not improve prediction of cardiac surgery-associated acute kidney injury by Douville, Nicholas J, Larach, Daniel B, Lewis, Adam, Bastarache, Lisa, Pandit, Anita, He, Jing, Heung, Michael, Mathis, Michael, Wanderer, Jonathan P, Kheterpal, Sachin, Surakka, Ida, Kertai, Miklos D

“…The recent integration of genomic data with electronic health records has enabled large scale genomic studies on a variety of perioperative complications, yet…”
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Fabrication of Two-Layered Channel System with Embedded Electrodes to Measure Resistance Across Epithelial and Endothelial Barriers by Douville, Nicholas J, Tung, Yi-Chung, Li, Ran, Wang, Jack D, El-Sayed, Mohamed E.H, Takayama, Shuichi

“…This manuscript describes a straightforward fabrication process for embedding Ag/AgCl electrodes within a two-layer poly(dimethylsiloxane) (PDMS) microfluidic…”
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Genome-wide association study of cardiac troponin I in the general population by Moksnes, Marta R, Røsjø, Helge, Richmond, Anne, Lyngbakken, Magnus N, Graham, Sarah E, Hansen, Ailin Falkmo, Wolford, Brooke N, Gagliano Taliun, Sarah A, LeFaive, Jonathon, Rasheed, Humaira, Thomas, Laurent F, Zhou, Wei, Aung, Nay, Surakka, Ida, Douville, Nicholas J, Campbell, Archie, Porteous, David J, Petersen, Steffen E, Munroe, Patricia B, Welsh, Paul, Sattar, Naveed, Smith, George Davey, Fritsche, Lars G, Nielsen, Jonas B, Åsvold, Bjørn Olav, Hveem, Kristian, Hayward, Caroline, Willer, Cristen J, Brumpton, Ben M, Omland, Torbjørn

“…Abstract Circulating cardiac troponin proteins are associated with structural heart disease and predict incident cardiovascular disease in the general…”
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Nanoscale Squeezing in Elastomeric Nanochannels for Single Chromatin Linearization by Matsuoka, Toshiki, Kim, Byoung Choul, Huang, Jiexi, Douville, Nicholas Joseph, Thouless, M.D, Takayama, Shuichi

“…This paper describes a novel nanofluidic phenomenon where untethered DNA and chromatin are linearized by rapidly narrowing an elastomeric nanochannel filled…”
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