Search Results - "Doutch, J."

Effect of Formulation Method, Lipid Composition, and PEGylation on Vesicle Lamellarity: A Small-Angle Neutron Scattering Study by Nele, Valeria, Holme, Margaret N, Kauscher, Ulrike, Thomas, Michael R, Doutch, James J, Stevens, Molly M

“…Liposomes are well-established systems for drug delivery and biosensing applications. The design of a liposomal carrier requires careful choice of lipid…”
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Long-Range Electrostatic Colloidal Interactions and Specific Ion Effects in Deep Eutectic Solvents by Sanchez-Fernandez, Adrian, Jackson, Andrew J, Prévost, Sylvain F, Doutch, James J, Edler, Karen J

“…While the traditional consensus dictates that high ion concentrations lead to negligible long-range electrostatic interactions, we demonstrate that…”
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Ultrasound‐Triggered Enzymatic Gelation by Nele, Valeria, Schutt, Carolyn E., Wojciechowski, Jonathan P., Kit‐Anan, Worrapong, Doutch, James J., Armstrong, James P. K., Stevens, Molly M.

“…Hydrogels are formed using various triggers, including light irradiation, pH adjustment, heating, cooling, or chemical addition. Here, a new method for forming…”
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Adsorption and self-assembly properties of the plant based biosurfactant, Glycyrrhizic acid by Tucker, I.M., Burley, A., Petkova, R.E., Hosking, S.L., Penfold, J., Thomas, R.K., Li, P.X., Webster, J.R.P., Welbourn, R., Doutch, J.

“…[Display omitted] There is an increased interest in the use of natural surfactant as replacements for synthetic surfactants due to their biosustainable and…”
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Coupling Lipid Nanoparticle Structure and Automated Single‐Particle Composition Analysis to Design Phospholipase‐Responsive Nanocarriers by Barriga, Hanna M. G., Pence, Isaac J., Holme, Margaret N., Doutch, James J., Penders, Jelle, Nele, Valeria, Thomas, Michael R., Carroni, Marta, Stevens, Molly M.

“…Lipid nanoparticles (LNPs) are versatile structures with tunable physicochemical properties that are ideally suited as a platform for vaccine delivery and RNA…”
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Controlled Dendrimersome Nanoreactor System for Localized Hypochlorite-Induced Killing of Bacteria by Potter, Michael, Najer, Adrian, Klöckner, Anna, Zhang, Shaodong, Holme, Margaret N, Nele, Valeria, Che, Junyi, Massi, Lucia, Penders, Jelle, Saunders, Catherine, Doutch, James J, Edwards, Andrew M, Ces, Oscar, Stevens, Molly M

“…Antibiotic resistance is a serious global health problem necessitating new bactericidal approaches such as nanomedicines. Dendrimersomes (DSs) have recently…”
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Self-assembly in saponin mixtures: Escin/tea, tea/glycyrrhizic acid, and escin/glycyrrhizic acid mixtures by Tucker, I.M., Burley, A., Petkova, R.E., Hosking, S.L., Webster, J.R.P., Li, P.X., Ma, K., Doutch, J., Penfold, J., Thomas, R.K.

“…Saponins are plant based biosurfactants that are obtained from a wide variety of plant species. They are surface active glycosides with a hydrophobic group,…”
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Self-assembly in escin-nonionic surfactant mixtures: From micelles to vesicles by Tucker, IM, Burley, A, Petkova, RE, Hosking, SL, R P Webster, J, X Li, P, Ma, K, Doutch, J, Penfoldoo, J, Thomas, RK

“…[Display omitted] Hypothesis: Saponins are a class of plant derived surfactants which are widely used in food related foams and emulsions, aerated drinks, and…”
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Revealing Population Heterogeneity in Vesicle-Based Nanomedicines Using Automated, Single Particle Raman Analysis by Saunders, Catherine, Foote, James E. J., Wojciechowski, Jonathan P., Cammack, Ana, Pedersen, Simon V., Doutch, James J., Barriga, Hanna M. G., Holme, Margaret N., Penders, Jelle, Chami, Mohamed, Najer, Adrian, Stevens, Molly M.

“…The intrinsic heterogeneity of many nanoformulations is currently challenging to characterize on both the single particle and population level. Therefore,…”
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Self-assembly in saponin/surfactant mixtures: Escin and sodium dodecylsulfate by Tucker, I.M., Burley, A., Petkova, R.E., Hosking, S.L., Webster, J.R.P., Li, P.X., Ma, K., Doutch, J., Penfold, J., Thomas, R.K.

“…Saponins are a class of bio-surfactants obtained from a wide variety of plant species. They are surface active glycosides which are used in the stabilisation…”
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Ultraviolet Light Transmission through the Human Corneal Stroma Is Reduced in the Periphery by Doutch, James J., Quantock, Andrew J., Joyce, Nancy C., Meek, Keith M.

“…This article investigates in vitro light transmission through the human cornea in the ultraviolet (UV) portion of the electromagnetic spectrum as a function of…”
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Design of Lipid-Based Nanocarriers via Cation Modulation of Ethanol-Interdigitated Lipid Membranes by Nele, Valeria, Holme, Margaret N, Rashid, M. Harunur, Barriga, Hanna M. G, Le, Tu C, Thomas, Michael R, Doutch, James J, Yarovsky, Irene, Stevens, Molly M

“…Short-chain alcohols (i.e., ethanol) can induce membrane interdigitation in saturated-chain phosphatidylcholines (PCs). In this process, alcohol molecules…”
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The variation in transparency of amniotic membrane used in ocular surface regeneration by Connon, C J, Doutch, J, Chen, B, Hopkinson, A, Mehta, J S, Nakamura, T, Kinoshita, S, Meek, K M

“…Scant consideration has been given to the variation in structure of the human amniotic membrane (AM) at source or to the significance such differences might…”
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Potent Virustatic Polymer–Lipid Nanomimics Block Viral Entry and Inhibit Malaria Parasites In Vivo by Najer, Adrian, Blight, Joshua, Ducker, Catherine B., Gasbarri, Matteo, Brown, Jonathan C., Che, Junyi, Høgset, Håkon, Saunders, Catherine, Ojansivu, Miina, Lu, Zixuan, Lin, Yiyang, Yeow, Jonathan, Rifaie-Graham, Omar, Potter, Michael, Tonkin, Renée, Penders, Jelle, Doutch, James J., Georgiadou, Athina, Barriga, Hanna M. G., Holme, Margaret N., Cunnington, Aubrey J., Bugeon, Laurence, Dallman, Margaret J., Barclay, Wendy S., Stellacci, Francesco, Baum, Jake, Stevens, Molly M.

“…Infectious diseases continue to pose a substantial burden on global populations, requiring innovative broad-spectrum prophylactic and treatment alternatives…”
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Metal Cross-Linked Supramolecular Gel Noodles: Structural Insights and Antibacterial Assessment by Ghosh, Dipankar, Coulter, Sophie M., Laverty, Garry, Holland, Chris, Doutch, James J., Vassalli, Massimo, Adams, Dave J.

“…Achieving precise control over gelator alignment and morphology is crucial for crafting tailored materials and supramolecular structures with distinct…”
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Investigation of the Thermogelation of a Promising Biocompatible ABC Triblock Terpolymer and Its Comparison with Pluronic F127 by Constantinou, Anna P, Nele, Valeria, Doutch, James J, S. Correia, Joana, Moiseev, Roman V, Cihova, Martina, Gaboriau, David C. A, Krell, Jonathan, Khutoryanskiy, Vitaliy V, Stevens, Molly M, Georgiou, Theoni K

“…Thermoresponsive polymers with the appropriate structure form physical networks upon changes in temperature, and they find utility in formulation science,…”
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Tuneable peptide cross-linked nanogels for enzyme-triggered protein delivery by Massi, Lucia, Najer, Adrian, Chapman, Robert, Spicer, Christopher D, Nele, Valeria, Che, Junyi, Booth, Marsilea A, Doutch, James J, Stevens, Molly M

“…Many diseases are associated with the dysregulated activity of enzymes, such as matrix metalloproteinases (MMPs). This dysregulation can be leveraged in drug…”
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How does the hydrophobic content of methacrylate ABA triblock copolymers affect polymersome formation? by Zhang, Xinmo, Contini, Claudia, Constantinou, Anna P., Doutch, James J., Georgiou, Theoni K.

“…Polymersomes are exciting self‐assembled structures with great potential in pharmaceutical applications. A systematic investigation of a novel series of…”
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Elongation rate and average length of amyloid fibrils in solution using isotope-labelled small-angle neutron scattering by Eves, Ben J, Doutch, James J, Terry, Ann E, Yin, Han, Moulin, Martine, Haertlein, Michael, Forsyth, V. Trevor, Flagmeier, Patrick, Knowles, Tuomas P. J, Dias, David M, Lotze, Gudrun, Seddon, Annela M, Squires, Adam M

“…We demonstrate a solution method that allows both elongation rate and average fibril length of assembling amyloid fibrils to be estimated. The approach…”
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Structural Changes from Native Waxy Maize Starch Granules to Cold-Water-Soluble Pyrodextrin during Thermal Treatment by Bai, Yanjie, Cai, Liming, Doutch, James, Gilbert, Elliot P, Shi, Yong-Cheng

“…The structural changes occurring during the thermal conversion of insoluble native waxy maize starch granules to cold-water-soluble pyrodextrin under acidic…”
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