Search Results - "Doustvandi, Mohammad Amin"
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Photodynamic therapy for cancer: Role of natural products
Published in Photodiagnosis and photodynamic therapy (01-06-2019)“…•Photodynamic therapy as potential strategy in cancer treatment.•Tumor destruction mechanisms via PDT.•PDT in combination with herbal medicine in…”
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MicroRNAs and their vital role in apoptosis in hepatocellular carcinoma: miRNA-based diagnostic and treatment methods
Published in Gene (20-12-2023)“…•MiRNAs play crucial roles in the progression of HCC, which regulate gene expression through post-transcriptional inhibition and targeting mRNA degradation in…”
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Dual silencing of tumor-intrinsic VISTA and CTLA-4 stimulates T-cell mediated immune responses and inhibits MCF7 breast cancer development
Published in Gene (20-02-2024)“…As inhibitory immune checkpoint molecules, cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) and V-domain Ig suppressor of T-cell activation (VISTA) can be…”
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Combination of B7H6-siRNA and temozolomide synergistically reduces stemness and migration properties of glioblastoma cancer cells
Published in Experimental cell research (01-08-2023)“…Glioblastoma multiforme (GBM) is among the malignant brain tumors of the central nervous system (CNS). The survival of this disease is about 14 months after…”
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Sodium metabisulfite as a cytotoxic food additive induces apoptosis in HFFF2 cells
Published in Food chemistry (01-10-2021)“…•Cytotoxic effects of SMB were investigated on HFFF2 cells.•SMB reduced cell viability and induced apoptosis.•SMB modulated the expression of genes involved in…”
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Alpha7 nicotinic acetylcholine receptors in lung inflammation and carcinogenesis: Friends or foes?
Published in Journal of cellular physiology (01-09-2019)“…The lung tissue expresses the cholinergic system including nicotinic acetylcholine receptors (nAChRs) which included in many physiologic and pathologic…”
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Photodynamic Therapy with Zinc Phthalocyanine Inhibits the Stemness and Development of Colorectal Cancer: Time to Overcome the Challenging Barriers?
Published in Molecules (Basel, Switzerland) (15-11-2021)“…Photodynamic therapy (PDT) is a light-based cancer therapy approach that has shown promising results in treating various malignancies. Growing evidence…”
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Suppression of human papillomavirus type 16 E5 oncoprotein: A promising step in fostering the treatment of cervical cancer
Published in Oncology research (01-01-2021)“…Cervical cancer is a growing global disease in developing countries. Persistent infection with human papillomaviruses (HPV) is an essential causative agent in…”
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Combination therapy with miR-34a and doxorubicin synergistically induced apoptosis in T-cell acute lymphoblastic leukemia cell line
Published in Medical oncology (Northwood, London, England) (01-12-2021)“…MicroRNAs are identified to take actively part in the development of different cancers. Reduced expression of tumor suppressor miRNAs leads to cancer cell…”
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Simultaneous suppression of miR-21 and restoration of miR-145 in gastric cancer cells; a promising strategy for inhibition of cell proliferation and migration
Published in Bioimpacts (2024)“…Introduction: Around the world, gastric cancer (GC) is the third leading cause of cancer-related deaths. microRNAs are a group of regulatory non-coding RNAs…”
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MiR-145 inhibits cell migration and increases paclitaxel chemosensitivity in prostate cancer cells
Published in Iranian journal of basic medical sciences (2023)“…Objective(s): Prostate cancer (PC) is one of the most commonly diagnosed malignancies among men worldwide. Paclitaxel is a chemotherapeutic agent widely used…”
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Cooperatively inhibition effect of miR-143-5p and miR-145-5p in tumorigenesis of glioblastoma cells through modulating AKT signaling pathway
Published in Bioimpacts (2024)“…Introduction: As the most common aggressive primary brain tumor, glioblastoma is inevitably a recurrent malignancy whose patients’ prognosis is poor. miR-143…”
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Human cardiac organoids: A recent revolution in disease modeling and regenerative medicine
Published in Journal of cardiovascular and thoracic research (01-06-2023)“…Three-dimensional (3D) myocardial tissues for studying human heart biology, physiology and pharmacology have recently received lots of attention. Organoids as…”
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The Effects of siRNA-Mediated Gene Silencing of Alpha-7 Nicotinic Acetylcholine Receptors on Drug Resistance to Oxaliplatin in Colorectal Cancer Cells
Published in Biology bulletin of the Russian Academy of Sciences (01-12-2022)“…The role of alpha-7 nicotinic acetylcholine receptor (α7nAchR) in colorectal cancer (CRC) chemoresistance, especially in Oxaliplatin (OXA)-resistant cells, has…”
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The dual role of alpha7 nicotinic acetylcholine receptor in inflammation-associated gastrointestinal cancers
Published in Heliyon (01-03-2020)“…Alpha7 nicotinic acetylcholine receptor (α7nAChR) is one of the main subtypes of nAChRs that modulates various cancer-related properties including…”
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Alpha7 Nicotinic Acetylcholine Receptor Mediates Nicotine-induced Apoptosis and Cell Cycle Arrest of Hepatocellular Carcinoma HepG2 Cells
Published in Advanced pharmaceutical bulletin (01-01-2020)“…Purpose: The cytotoxic properties upon treatment with nicotine have been reported in several studies, but the underlying mechanisms remain not fully defined…”
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Nicotinic Acetylcholine Receptor Subunit Alpha-7 Mediates PD-L1 and CTLA-4 Expression in HepG2 Cells
Published in ImmunoAnalysis (28-12-2021)“…Background: The liver is the largest solid organ in the body and has several unique immunological roles. The alpha7 subtype of nicotinic acetylcholine receptor…”
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Glioblastoma therapy: State of the field and future prospects
Published in Life sciences (1973) (15-12-2024)“…Glioblastoma (GB) is a cancerous brain tumor that originates from glial cells and leads to thousands of deaths each year and a five-year survival of only…”
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Combination of SIX4-siRNA and temozolomide inhibits the growth and migration of A-172 glioblastoma cancer cells
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-10-2023)“…Glioblastoma is one of the most common and invasive types of primary brain malignancies in adults, accounting for 45.5% of malignancies. Its annual prevalence…”
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MicroRNA-143 Sensitizes Cervical Cancer Cells to Cisplatin: a Promising Anticancer Combination Therapy
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-07-2021)“…Cisplatin-based chemotherapy is commonly used for cervical cancer treatment. However, the development of chemoresistance is considered the main obstacle to the…”
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